Browsing by Author "Joshi, Suchita"
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Publication A fatal case of congenital surfactant deficiency caused by ABCA 3 gene mutation in a newborn Authors(Nepalese Respiratory Society, 2022) Ghimire, Deen Dayalu; Joshi, SuchitaAbstract: Respiratory distress syndrome is a common cause for admission in neonatal intensive care unit and is predominant in preterm infants. Rarely, this can cause respiratory distress in full term infants. Here, we present a case of a full term baby without any other obvious cause for respiratory distress and transiently responding to surfactant administration, who eventually died at 1 month of age. As her elder sibling had also died following similar course of illness, congenital surfactant deficiency was suspected and blood sample for genetic testing was sent. This revealed ABCA 3 mutation as the cause of congenital surfactant deficiency.Publication Culture and Sensitivity Pattern of Urinary Tract Infection in Hospitalized Children in Patan Hospital(Nepal Paediatric Society (JNPS), 2016) Amatya, Puja; Joshi, Suchita; Shrestha, ShrijanaAbstract: Introduction: Urinary tract infection is one of the most common infections in children. Antibiotics are usually given empirically before urine culture reports are available. The primary aim of this study was to see the causative organisms and culture and sensitivity pattern of urinary tract infection in hospitalized children. Material and Methods: All children aged 0-15 years with culture positive urinary tract infections who were admitted to children’s ward from 14th April 2013 to 14th April 2014 were included. The causative organisms for urinary tract infection along with its antibiotic sensitivity pattern were retrospectively reviewed and analyzed. Results: 48 cases of culture positive urinary tract infection were enrolled in this study in a period of 12 months. The most common causative organism was Escherichia coli (67%), followed by Klebsiella pneumoniae (21%), Non-hemolytics streptococcus (4%), Enterobacter (2%), Acinetobacter (2%), Proteus (2%) and Coagulase negative staphylococcus (2%). Most cases of the culture positive urinary tract infection occurred between 2 months to 1 year of age. Out of 48 cases, 90% were sensitive to Amikacin and 85% were resistant to Ofloxacin. Conclusion: Escherichia coli is the most common organism causing urinary tract infection in children. As resistant to first line antibiotic is increasing, antibiotic stewardship programme should be strengthened.Publication Nepal Pediatric Society Guidelines for the Safe Transport of Critically Ill Children in Nepal(Nepal Paediatric Society (JNPS), 2021) Amatya, Puja; Shrestha, Dhruba; Joshi, Suchita; Sharma, Arun; Shrestha, Shrijana; Basnet, SangitaAbstract: Transport of critically ill children is associated with increased risk of morbidity and mortality in developing countries due to the lack of adequate resources and skilled personnel. Transport of the sick child remains a major challenge in Nepal as well. The main objective of this article is to describe the importance of safe transport, and be a resource and guide for health care personnel during inter-facility transport of sick children in Nepal. This guideline is based on consensus statement of Nepal Pediatric Critical Care Working Group (NPCCWG) under the aegis of the Nepal Pediatric Society (NEPAS). It includes different components of transport, namely essential equipment, patient preparation, communications, medications, and transport checklist, that are required during transport of sick children, taking into consideration the current resources available in our health care facilities.