Browsing by Author "Kaiti, Raju"
Now showing 1 - 3 of 3
Results Per Page
Sort Options
Publication Clinical Profile of posterior segment in high Myopia(Nepal Health Research Council, 2024) Kaiti, Raju; Bogati, Birkha; Shyangbo, Ranjila; Khadka, Simanta; Bajgai, PriyaBackground: Myopia is a growing global health concern, with prevalence surging, especially in East and Southeast Asia. The World Health Organization identifies high myopia as -5.00 diopter or less, carrying an elevated risk of irreversible blindness. In 2020, an estimated 2.6 billion people had myopia, projected to reach 4.7 billion by 2050, leading to a rise in complications like myopic maculopathy. This study, conducted in Nepal, where 47.16% of the population is myopic, aims to assess fundus and optic nerve changes in high myopia, examining associations with age, gender, axial length, and mean spherical error. Methods: A prospective, cross sectional study was conducted by recruiting 98 high myopic eyes (defined as spherical equivalent of <-5.0 diopters (D) or axial length ≥ 26.00 mm). Colored Fundus photography was performed on viewing angle of 500 in different field of gazes following pupillary dilatation. Fundus photographs were graded by independent graders to evaluate for high myopic fundus and optic disc changes. Multinomial logistic regression was performed with axial length and mean spherical error as risk and myopic changes as dependent variable. Results: In this study, tessellated fundus (57.1%) and peripapillary atrophy (40.8%) were the most common posterior segment changes in high myopic Nepalese subjects. High myopic features were seen in 45.9% of cases. Increase in axial length and mean spherical error was established as a risk factor for development of high myopic changes in the fundus. Conclusions: In this study of the highly myopic Nepalese population visiting tertiary eye hospital, myopic changes such as tessellated fundus and peripapillary atrophy were frequent and were associated with axial length and mean spherical error. Keywords: Degenerative myopia; high myopia; pathologic myopia; peripapillary atrophy; tessellated fundus.Publication Mean Amplitude of Diurnal Variation of Sub-Foveal Choroidal Thickness among Adults with Healthy Eyes Visiting Outpatient Department of a Tertiary Eye Care Centre(Nepal Medical Association, 2024) Kaiti, Raju; Bajgai, Priya; Shyangbo, RanjilaAbstract Introduction: The choroid, particularly the choroidal vasculature, plays an important role in the pathophysiology of various ocular diseases. Diurnal variation in the thickness of the choroid has been reported in previous studies. This study aimed to find the mean amplitude of diurnal variation of sub-foveal choroidal thickness among adults with healthy eyes visiting the outpatient Department of a tertiary eye care centre. Methods: A descriptive cross-sectional study was conducted among adults with healthy eyes presenting to the outpatient Department of a tertiary eye care centre from 1 February 2023 to 3 June 2023 after obtaining ethical approval from the Institutional Review Committee. After a comprehensive medical eye examination, sub-foveal choroidal thickness measurement was performed using enhanced depth imaging optical coherence tomography at the baseline and subsequent interval afterwards. A convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval. Results: Among 60 eyes, the mean amplitude of the diurnal variation of subfoveal choroidal thickness was 35.16±14.08 microns (31.59-38.72, 95% Confidence Interval). The mean amplitude for the right eye was 36.30±14.08 microns, and for the left eye, it was 34.23±14.08 microns Conclusions: The amplitude of diurnal variation of subfoveal choroidal thickness from this study was found to be similar to other studies done in international settings.Publication Positive Microbiological Culture among Patients with Infective Keratitis Visiting the Cornea Unit of a Tertiary Care Centre(Nepal Medical Association, 2023) Joshi, Leesha Shrestha; Kaiti, Raju; Shyangbo, Ranjila; Bogati, BirkhaAbstract Introduction: Keratitis is the infection and inflammation of the cornea. Microbial keratitis is a potentially sight-threatening corneal condition. The aim of this study was to find out the prevalence of positive microbiological culture among patients with infective keratitis visiting the Cornea Unit of a tertiary care centre. Methods: A descriptive cross-sectional study was conducted among patients with a clinical diagnosis of infective keratitis presenting to the Cornea Unit of a tertiary eye care centre from 16 October 2020 to 16 March 2021 after obtaining ethical approval from the Ethical Review Board. After slit-lamp examination, corneal scrapings were performed under aseptic conditions which were subjected to Gram stain, potassium hydroxide preparation and culture for bacterial and fungal pathogens. A convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval. Results: Among 428 patients, 337 (78.73%) (73.24-84.33, 95% Confidence Interval) had a positive microbiological culture. A total of 213 (49.76%) of enrolled samples had a prior history of ocular trauma. Aspergillus species 68 (20.17%) and Streptococcus species 33 (9.79%) were the most common organisms isolated from fungal and bacterial corneal ulcers respectively. Conclusions: The prevalence of positive microbiological culture among patients with infective keratitis from this study is similar to the pattern reported from similar settings.