Browsing by Author "Karki, Anup"
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Publication Penile Fracture: A Case Report(Nepal Medical Association, 2022) Yogi, Prajwala; Sapkota, Shova; Shiwakoti, Samir; Dongol, Udaya Man Singh; Paudyal, Prajwal; Karki, AnupAbstract Penile fracture is a rare condition with an incidence of 1 case per 175000 United States male population. It can be caused by vigorous sexual intercourse and masturbation. Patients usually present with pain and swelling of the penis and can be diagnosed clinically. It mostly occur as a result of rupture of tunica albuginea of corpora cavernosa. Ultrasound is the most reliable investigation to detect penile fractures. Patients need prompt treatment with exploration and repair of defects to prevent long-term sequelae. Here we present a case of 44 years male who developed a penile fracture following sexual intercourse and underwent surgical exploration and repair.Publication Prevalence of COVID-19 Positive Cases Diagnosed by Real time Polymerase Chain Reaction in a Tertiary Care Hospital of Nepal(Nepal Medical Association, 2021) Pokharel, Khilasa; Mishra, Bhavesh; Karki, AnupAbstract: Introduction: The virus that causes COVID-19 is known as severe acute respiratory syndrome Coronavirus-2. This new variant of Corona Virus introduced in China has urged the massive health system resources to focus on its screening and management of sick patients worldwide. We aimed to find the prevalence of COVID-19 positive cases diagnosed by Real-time polymerase chain reaction in a tertiary care hospital of Nepal. Methods: This is a descriptive cross-sectional study that was conducted from 11th of November to 15th December 2020. Nasopharyngeal and Oropharyngeal swabs were collected, and confirmation of cases of COVID-19 was done based on the detection of viral ribonucleic acid by nucleic acid amplification tests such as real-time reverse transcriptase-polymerase chain reactions. The viral genes targeted include the E, N, and ORF. Results: A total of 15247 samples have been processed, of which s (14.81%) positive cases were included in this study. There were 1427 (63.19%) male and 831 (36.68%) females. The majority of the cases were asymptomatic 1386 (61.38%). The most common age group infected was between 15 to 40 years, 841 (58.93%) male and 542 (65.22%) females. The most common presenting symptoms were cough 315 (13.95%) and fever 306 (13.55%). Conclusions: Most of the individuals reported for real-time polymerase chain reaction were asymptomatic patients who might be contagious and have the potential to transmit infection. Among symptomatic cases, common symptoms were cough and fever.Publication Side Effects after Second Dose of Covishield Vaccine among Health Care Workers: A Descriptive Cross Sectional Study(Nepal Medical Association, 2021) Pokharel, Khilasa; Dawadi, Bishwa Raj; Karki, AnupAbstract: ABSTRACT Introduction: COVID 19 vaccination will protect us from getting COVID-19. Some side effects are common which are signs that our body is building protection. This side effects will go away in a few days. The aim of this study is to find out side effects seen among health care workers after second dose of covishield vaccination. Methods: This was a descriptive cross-sectional study conducted at Kathmandu medical college and Teaching Hospital from 22nd April 2021 till 30th April 2021. Ethical approval was revceived from Institutional Commitee of Institiute. Convienient sampling was done. The second dose of covishield vaccine was administered 12 weeks after its first dose. The vaccine was administered intramuscularly (IM) into deltoid muscle. Statistical Package for the Social Sciences were used for analysis. Results: Out of 220 cases taken, 135 were male and 85 were female. In our study 178 (80.90%) complaint of pain at injection site after second dose of covishield vaccine followed by 97 (44.09%) complaint of fatigue, 43 (19.54%) complaint of headache, 18 (8.18%) complaint of chills, 11 (5.00%)complaint of fever, 6 (2.72%) complaint of dizziness and 5 (2.27%) complaint of nausea. Conclusions: Pain at injection site, fatigue and headache were common side effects seen after second dose of Covishield vaccination.