Browsing by Author "Karki, Chandrima"
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Publication Multiple Pregnancy among Deliveries in a Tertiary Care Center: A Descriptive Cross-sectional Study(Nepal Medical Association, 2022) Bajagain, Rupa; Karki, Chandrima; Mahato, Shilpi; Saha, Rachana; Saha, NituAbstract Introduction: Multiple pregnancy is associated with increased obstetric complications as well as poor perinatal outcomes in developing countries because of the increased risk to both mother and baby. So better understanding of the risk factors is required to improve the quality of perinatal care. The aim of the study was to find out the prevalence of multiple pregnancies among deliveries in a tertiary care centre. Methods: A descriptive cross-sectional study was done among total deliveries in the Department of Obstetrics and Gynaecology of a tertiary care centre from inpatient records starting from 15 August 2020 to 15 February 2021 after obtaining ethical approval from the Institutional Review Committee (Reference number: 1208202005). Convenience sampling was done. Point estimate and 95% Confidence Interval were calculated. Results: Out of 4400 deliveries, multiple pregnancy was seen in 35 (0.79%) (0.53-1.06, 95% Confidence Interval). Conclusions: The prevalence of multiple pregnancies was similar to the studies done in similar settings.Publication Prevalence of Thyroid Disorder in Pregnant Women Visiting a Tertiary Care Teaching Hospital: A Descriptive Cross-sectional Study(Nepal Medical Association, 2021) Khakurel, Gita; Karki, Chandrima; Chalise, SanatAbstract: Introduction: The function of the thyroid gland is altered during pregnancy. Thyroid disorders during pregnancy are associated with serious maternal and fetal outcomes. Universal screening for thyroid disorders is recommended in the first trimester of pregnancy. This study aims to determine the prevalence of thyroid disorder during pregnancy in women attending a tertiary care hospital. Methods: A descriptive cross-sectional study was conducted in the Department of Obstetrics and Gynaecology of Kathmandu Medical College and Teaching Hospital from March 2020 to August 2020 after obtaining ethical approval from the Institutional Review committee with reference number 20032020. The pregnant women >18 years of age, irrespective of their gestational age and gravida status, were included in the study by convenience sampling method. The participants were screened by estimation of thyroid function test. Data were collected, and statistical analysis was done in Statistical Packages for Social Services version 20.0. Results: A total of 329 pregnant women were included in this study. The prevalence of thyroid disorders in the present study is 24.62 %. The most common thyroid disorder observed was subclinical hypothyroidism comprising 65 (19.75 %) cases followed by overt hypothyroidism 8 (2.43%) cases. Conclusions: There is a high prevalence of thyroid disorders during pregnancy in our settings. Timely screening of pregnant women helps in the early diagnosis and management of complications related to thyroid disorders.Publication Study of Vitamin-D Deficiency among Pregnant Women in their First Trimester Visiting a Tertiary Care Hospital: A Descriptive Cross-sectional Study Authors(Nepal Medical Association, 2021) Shrestha, Dipty; Saha, Rachana; Karki, Chandrima; Mahato, ShilpiAbstract: Introduction: Vitamin-D deficient pregnant women are more likely to have pregnancy complications like pre-eclampsia, intrauterine growth restriction, diabetes, preterm birth, etc. Associated factors include ethnicity, skin coverall, use of sun protection, overweight, vitamin-D intake, and smoking. The objective of this study is to determine the prevalence of Vitamin-D deficiency among pregnant women in a tertiary level hospital. Methods: This study descriptive cross-sectional study was conducted at a tertiary care hospital from September 15th, 2020 to November 15th, 2020 where the pregnant women visiting for an antenatal checkup in the first trimester were enrolled. Ethical clearance was taken from the Institutional Review Committee of Kathmandu Medical College (reference no. 1808202003). A convenience sampling method was used. All the data were entered in the Statistical Package of the Social Sciences version 20.0 and analyzed. Point estimate at 90% Confidence Interval was calculated along with frequency and percentage for binary data. Results: Among a total of 47 cases, vitamin-D deficiency was seen in 21 (44.6%) (32.67-56.52 at 90% Confidence Interval). Conclusions: The prevalence of vitamin-D deficiency was similar to other studies done in similar settings.