Browsing by Author "Karki, N"
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Publication Pattern of poisoning cases in Emergency Department of Kathmandu Medical College Teaching Hospital(Kathmandu University, 2008) Thapa, SR; Lama, P; Karki, N; Khadka, SBAbstract Objective: This study was conducted to determine the pattern and severity of poisoning cases in Emergency Department of Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal (KMCTH). Design: Retrospective observational study. Materials and methods: Hospital records of all admissions to the Emergency Department of Kathmandu Medical College Teaching Hospital (KMCTH) following acute poisoning were revised and all data from February 2007 to February 2008 were analyzed retrospectively. Results: This retrospective observational study was performed on 148 cases of poisoning who attended Emergency Department of KMCTH over a period of one year. The overall male to female ratio was 1.05:1. Poisoning was most common in the age group 21-30 years (40.5%). The most common causes of poisoning in adults were organophosphorous compounds and in children was kerosene oil. Oral route (79.05%) was the most common route of administration. 66.2% of cases were intentional poisoning for suicidal attempt. Students (43.9%) and service holders (18.9%) were commonly involved in poisoning. Conclusion: It was seen that adult between 21-30 years of age were more prone to suicidal poisoning with organophosphorous compounds and children of 1-10 years of age were more susceptible to accidental poisoning with kerosene oil. Key words: Kerosene, Organophosphorous, Poisoning, Suicide.Publication Prevalence of Hepatic Hydrothorax in Patients with Chronic Liver Disease Presenting in Tertiary Center of Nepal(Kathmandu University, 2024) Shankhadev, A; KC, S; Karki, N; Sharma, D; Pradhan, PABSTRACT Background Hepatic hydrothorax is a common cause of pleural effusion in chronic liver disease. It is associated with poor outcome of the disease. Objective To study the prevalence of hepatic hydrothorax in patient with chronic liver disease. Method A hospital based prospective observational study conducted from July 15, 2022 to July 15, 2023. Diagnostic thoracentesis was performed to the patients presenting with pleural effusion at the time of admission. Chest x-ray was repeated at day 7 to assess the outcome of the appropriate treatment. Result Out of 752 enrolled participants, 105 were diagnosed with pleural effusion. The predominant cause was hepatic hydrothorax (80%), followed by tuberculosis (13.3%). 26.2% experienced spontaneous bacterial empyema. Most of the patients (74%) were classified as Child-Pugh C score. The prevalence of hepatic hydrothorax was 11.17%. Among 84 patients with hepatic hydrothorax, the mean age was 49.42±11.93 years, with a male predominance (male to female ratio, 68:32). Hepatic hydrothorax primarily occurred on the right side (78.6%), followed by left (15.5%) and bilaterally (6%). Mild hepatic hydrothorax was most common (48.8%), followed by moderate (31%) and massive (20.2%). About 65.5% were improved with treatment, while the mortality rate was 34.52%. Renal causes were the most common cause of death, accounting for 58.62% of mortalities. Conclusion Hepatic hydrothorax was prevalent in 11.17% of patients. It predominantly occurred on right side, with advanced Child Pugh score and often associated with spontaneous bacterial empyema (26.2%). The condition carried a mortality rate of 34.52%, with renal causes accounting for the majority of deaths (58.62%). All pleural effusions in chronic liver disease should undergo prompt evaluation because it is often associated with various complications and carries high mortality rate. KEY WORDS Ascites, Chronic liver disease, Hepatic hydrothorax, Prevalence, Spontaneous bacterial empyema, Tuberculosis