Browsing by Author "Khadka, Manita"
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Publication Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report Authors(Nepal Medical Association, 2021) Basnet, Angela; Ojha, Shiva Kumar; Jha, Suman Kumar; Paudyal, Anjana; Khadka, Manoj; Khadka, Manita; Shrestha, Dhan BahadurAbstract: Nepal started the COVID-19 vaccination on 27 January 2021 with AstraZeneca/Oxford Coronavirus Disease-19 AZD1222 (Covishield) vaccine to control the Coronavirus disease pandemic. The vaccine has a good safety profile, with cardiovascular complications being rare. Herein we report a rare case of cardiovascular complication following Covishield vaccination in a 33 years old female who had dizziness and elevated blood pressure immediately following vaccination and abnormal electrocardiogram showing T wave inversions followed by left bundle branch block. The patient was kept on observation, following which the blood pressure and electrocardiogram changes were normal by seven days. This cardiovascular complication following the vaccination demands further investigation into the adverse event of the vaccine. However, since the benefit of the vaccine outweighs the risk, World Health Organization has recommended the continuity of the vaccine as of now.Publication Empyema Thoracis in a Patient Admitted with COVID-19: A Case Report Authors(Nepal Medical Association, 2021) Basnet, Angela; Chaulagain, Sabin; Thapa, Ashok; Khadka, Manita; Khadka, Manoj; Shrestha, Dhan BahadurAbstract: After almost a year of declaring COVID-19 a global pandemic, unusual presentations of the disease continue to be reported. Very little is known about its association with pleural disease. Here, we present a case of empyema thoracis in a 39-year-old male admitted with COVID-19. The pleural fluid later turned serosanguinous and eventually bleeding from other sites also occurred. During his treatment, antibiotics were given, thoracocentesis was performed and later thoracotomy was done. He died on the 19th day of admission following a hemorrhagic stroke. Pleural disease, although considered atypical and unusual presentation of COVID-19, needs careful and prompt diagnosis and earliest intervention. COVID-19, being a disease that involves multiple systems, and presentation of the disease may eventually lead to circulatory dysfunction and hence should be kept under consideration.