Browsing by Author "Khatri, Prabin"
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Publication HLA-B27 Negative Reactive Monoarthritis of the Hip Joint Triggered by Scrub Typhus: A Case Report(Nepal Medical Association, 2023) Khatri, Prabin; Upadhyaya, Ashutosh; Kandel, Nirajan; Upadhyaya, Shriya; Panth, HimalAbstract Scrub typhus is common in rural Nepal's southern plains, but its diagnosis remains difficult due to a lack of clinical suspicion and poor diagnostic resources. The absence of common manifestations of the condition including eschar might further complicate this problem and may result in treatment delays. We report a case of scrub typhus with the primary presentation of reactive monoarthritis of the left hip joint in a 19-year-old male who presented with difficulty in walking, and pain over the left hip joint. Ultrasonography of the left hip and thigh showed features of synovitis and iliopsoas bursitis. After a meticulous workup, a diagnosis of human leukocyte antigen B27 negative reactive monoarthritis of the left hip joint triggered by scrub typhus infection was made and the patient was treated with doxycycline. Delays in treatment and the rate of complications can be prevented with high clinical suspicion and awareness of the atypical presentation of the condition.Publication Primary Sjogren’s Syndrome with Bicytopenia: A Case Report(Nepal Medical Association, 2024) Pathak, Deepankar Raj; Chaurasiya, Ashish Kumar; Subedi, Rasish; Khatri, Prabin; Shah, PoojaAbstract Sjogren’s syndrome is a chronic multisystem autoimmune disease presenting a wide variety of clinical manifestations ranging from mild sicca symptoms to severe systemic symptoms involving pulmonary, renal, musculoskeletal, cutaneous, and haematological diseases. These symptomatic diversities can delay the correct diagnosis of Sjogren’s Syndrome for a long time. Here, we report the case of a 59-year-old woman with fatigue and weakness in whom bicytopenia was documented. A thorough bicytopenia workup brought us to the final diagnosis of Sjogren’s syndrome. Hydroxychloroquine was started which normalized the patient’s blood parameters and clinical symptoms. The haematological alterations in Sjogren’s syndrome are not pathognomonic. However, only bicytopenia can be the initial presentation of Sjogren’s syndrome as in our patient. Therefore, inexplicable bicytopenia in a middle-aged female may alert the clinician about the possibility of Sjogren’s syndrome.