Browsing by Author "Khattri, JB"
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Publication A Study of Vitamin D among Patients Presenting in the Psychiatric OPD of Manipal Teaching Hospital, Pokhara(Kathmandu University, 2019) Khattri, JB; Godar, ST; Subedi, AABSTRACT Background There have been growing interests in the association between vitamin D and depression in recent years. Objective The objective of this study was to find the prevalence of low vitamin D level in the patients suffering from depressive episodes. The next objective was to determine whether there are any statistically significant differences between the mean vitamin D levels of different sociodemographic variables and also to find the socio- demographic variables predicting the vitamin D level. Method The patients diagnosed as depressive episodes were selected from the out-patient unit of Department of Psychiatry of Manipal Teaching Hospital, Pokhara. The proforma was used to collect the sociodemographic profile of the patient. The diagnosis of depressive episode was made according to the International Classification of Disease-10 Classification of Mental and Behavioural Disorders: Diagnostic Criteria for Research. The serum vitamin D level of less than 30 ng/ml was considered as low level in this study. Result The prevalence of low vitamin level was found in 81.8%. The mean difference of vitamin D level was statistically significant in gender and marital status of the patients. The low mean vitamin level was found in the socio-demographic variables like in age above 60 years, Newar caste, female gender, separated from the spouse patients and in the patients living in the urban area as compared to other group of patients. The gender of the patients predicted vitamin D level in the depressed patients. Conclusion There is high prevalence of low vitamin D level in the depressed patients. The correction of low vitamin D level would be helpful in the holistic management of patient with depressive episodes. KEY WORDS Depression, Prevalence, Vitamin DPublication Delirium in Critically ill Patients in a Tertiary Care Centre in Western Region of Nepal(Kathmandu University, 2014) Thapa, P; Chakraborty, PK; Khattri, JB; Ramesh, K; Sharma, PABSTRACT Background Delirium affects a significant proportion of critically ill patients admitted in hospital. It is associated with various adverse outcomes. Despite its enormous prognostic significance it tends to be underdiagnosed. There is a dearth of studies on risk factors of delirium in our setting. Objectives The main objectives of this study was to find out the prevalence, rate of non recognition and risk factors associated with delirium in hospitalized critically ill patients. Methods A hospital based cross-sectional study was carried out. Data was collected using a predesigned semi-structured proforma and Intensive care delirium screening checklist was used to screen for delirium in patients admitted in various wards of Manipal teaching hospital, Pokhara, Nepal. Results Ninety five cases were included in the analysis. The mean age of study group was 58.9 ± 19.1 years. Delirium was present in 15/95 cases and it was not recognized by treating physician in about one third of cases. Odds ratio (OR) was statistically significantly increased in patients with history of stroke (OR=4.484 95% CI=1.0896;18.459), alcohol use (OR=10.792 95% CI=2.906;40.072), smoking (OR= 4.836 95% CI= 1.411;16.576), use of restraint (OR=17.143 95% CI=4.401;66.766), nasogastric tube placement (OR= 7.731 95% CI=2.348;25.452) and use of Foley’s catheter (OR=12.000 95% CI= 3.072;46.877). Conclusion About 16% of critically ill patients were found to be delirious. In about one third of the cases delirium was not recognized. Both patient related and iatrogenic factors may increase the risk of delirium in hospitalized critically ill patients. KEY WORDS Critical care, delirium, non-recognition