Browsing by Author "Kunwar, Meena"
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Publication Positive Bacterial Culture among Suspected Orthopedic Infections in a Tertiary Care Centre: A Descriptive Cross-sectional Study(Nepal Medical Association, 2022) Pradhan, Ishor; Regmi, Subhash; Kunwar, Meena; Basukala, Bibek; Joshi, AmitAbstract Introduction: A hospital-based investigation of bacteriological isolates helps to identify common causative bacteria and their antibiotic sensitivity patterns. This helps in formulating presumptive antibiotic therapy and in reducing antibiotic misuse. The aim of this study was to find out the prevalence of positive bacterial culture isolates among suspected orthopaedic infections in a tertiary care centre. Methods: A descriptive cross-sectional study was conducted from the electronic data record of the Department of Microbiology of a tertiary care centre from 1 January 2017 to 31 December 2021. The study was conducted following ethical approval from the Institutional Review Committee (Reference number: IRC-2021-11-09-1). Culture reports of suspected orthopaedic infections were evaluated, and those with missing data were excluded. A convenience sampling method was used. Point estimate and 95% Confidence Interval were calculated. Results: Out of 6201 specimens, positive bacterial culture were found in 2957 (47.69%) (46.45-48.93, 95% Confidence Interval). Among them, 1561 (56.01%) were gram-negative organisms and 677 (24.29%) were gram-positive. A total of 2787 (94.25%) were wound/pus swab cultures and 170 (5.74%) were tissue cultures. Conclusions: The prevalence of positive bacterial culture among suspected orthopaedic infections was lower than in other international studies. Among bacteriological isolates, gram-negative organisms are more than gram-positive organisms.Publication Prevalence of Diabetic Retinopathy among Diabetic Patients Attending a Tertiary Care Hospital in Nepal: An Observational Study(Nepal APF Hospital, 2026) Chhetri, Sundip Dware; Shrestha, Apurba; Thapa, Ashish; Sah, Dayanand Prasad; Kunwar, Meena; Lamichhane, KritiAbstract: Introduction: The global rise of type II diabetes has increased the number of individuals at risk for retinal complications such as diabetic retinopathy, a leading cause of vision impairment. In Nepal, a significant number of patients are diagnosed with diabetic retinopathy only at advanced stages. Diabetic retinopathy is commonly linked to longer duration of diabetes, uncontrolled blood sugar, and elevated blood pressure. Timely detection and management are crucial to prevent irreversible vision loss. This study aimed to assess the prevalence of diabetic retinopathy among diabetic patients visiting a tertiary care hospital. Methods: A hospital-based observational study was conducted between September 1, 2025 and December 26, 2025, at a tertiary care hospital. Ethical approval was obtained from the Institutional Review Committee (Reference number: NAPFH-041/2025). Detailed demographic, clinical, and ocular examination findings were recorded. A purposive sampling technique was used. Data were analyzed with Microsoft Excel and Statistical Package for the Social Sciences version 17. Results: Out of 195 diabetic patients, the mean age was 54.7±10.17 years. The overall prevalence of diabetic retinopathy was 18 (9.23%), of which 17 (8.71%) had non-proliferative diabetic retinopathy, and 1 (0.51%) had proliferative diabetic retinopathy. Diabetic macular edema was present in 1 (0.51%) of cases. Diabetic retinopathy was more common in patients with longer duration of diabetes and associated complications, including nephropathy. Conclusions: Diabetic retinopathy continues to be a major complication among patients with diabetes in Nepal, with many cases identified late due to inadequate prior eye screening. Regular monitoring and early treatment are vital to avoid vision-threatening consequences.