Browsing by Author "Lama, B"
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Publication Analysis of Lung Cancer Cases Presenting in Outpatient Department of University Hospital of Nepal(Kathmandu University, 2022) Karmacharya, RM; Singh, AK; Vaidya, S; Tuladhar, SM; Devbhandari, M; Lama, B; Kharel, BB; Basnet, SABSTRACT Background Lung cancer is one of the leading cause of cancer related death. Most common histopathology of lung cancer is non-small cell carcinoma of which adenocarcinoma is the most common. There are limited number of studies done in Nepal to know different aspects of lung cancer. Objective To know demographic parameters of patients diagnosed as lung cancer in a university hospital. The study also aims to know the different histopathological diagnosis of lung cancer. Method All the patients presenting to outpatient department (Cardio Thoracic and Vascular unit) of Dhulikhel Hospital, if are diagnosed as cancer of lung/bronchus will be included in the study. The duration of the study was January 2017 to December 2021. The details on age, gender, presenting symptoms, histopathology of lung cancer, operability will be included in database and will be analyzed. Result There were total of 127 patients diagnosed as lung cancer. Male:female ratio was 1.7:1. Overall mean age was 63.23 years (SD 13.5 years, Range 19-89 years). Non small cell carcinoma was the most common type of lung cancer with 83.7%. In non small cell carcinoma, most common type was Squamous cell carcinoma followed by undifferentiated and Adenocarcinoma. Only five (3.93%) cases were in operable stage. Conclusion Despite the fact that lung cancer is one of the most common cancer, patients usually present late and moslty are not in operable stage. This study shows that squamous cell carcinoma is the most common histopathology in lung cancer cases. KEY WORDS Lung Cancer, Smoker, ThoracotomyPublication Appendiceal Neuroendocrine Tumor Mimicking Acute Appendicitis(Kathmandu University, 2022) Gautam, N; Makaju, R; Basnet, D; Lama, B; Maharjan, PB; Dahal, SABSTRACT Appendiceal carcinoids are the most frequent tumors arising from the appendix, comprising between 32 and 57% of all the appendiceal tumors. The gross appearance of the appendix showed perforation at the tip with 30 ml of periappendicular collection. On histopathological examination, carcinoid tumor on the tip of appendix was found with tumor cells arranged in tubules, acini and nests infiltrating the muscularis propria and sub serosa. Perineural and vascular invasion was not seen. Immunohistochemistry for Synaptophysin was positive with Ki-67 labelling index of 2%. We present a case of appendiceal neuroendocrine tumor with the chief complaint of acute appendicitis. KEY WORDS Appendectomy, Appendix, Carcinoid tumorPublication Cartilaginous Choristoma of Tonsil: A hidden clinical entity(Kathmandu University, 2021) Gautam, N; Makaju, R; Basnet, D; Lama, B; Maharjan, PBABSTRACT Choristoma is a tumor like mass which is an ectopic rest of normal tissue due to embryological developmental defect. The presence of choristoma in tonsil is extremely rare. On histopathological examination, mature hyaline cartilage were found surrounded by lymphoid follicles. We present a case of cartilaginous choristoma with the complaint of recurrent tonsillitis. KEY WORDS Cartilaginous choristoma, TonsilPublication Endometriosis of Groin Mimicking Neoplasm(Kathmandu University, 2021) Maharjan, PB; Makaju, R; Makaju, S; Dhakal, R; Lama, B; Basnet, D; Dhakal, BABSTRACT Endometriosis is principally a disease of women in active reproductive life. Although it is rare, foci of endometrial tissue may be seen in the bowel, the umbilicus, abdominal surgical scars and in the lungs. Inguinal endometriosis is challenging to the clinicians and pathologist and often diagnosed accidentally. We present a case of inguinal endometriosis mimicking neoplasm. A 40 year old woman presented with a swelling in the right inguinal region associated with cyclical pain. In view of presence of atypical cells in fine needle aspiration cytology, metastatic carcinoma was rendered as diagnosis. Histopathological examination revealed endometrial glands and stroma which was further confirmed by immunohistochemistry. Diagnosis of inguinal endometriosis is difficult and often challenging because of unusual site. The clinician must have high index of suspicion with any patient who has cyclical symptoms. A good history and physical examination can guide clinical diagnosis of endometriosis. KEY WORDS Endometriosis, Groin mass, Inguinal endometriosis