Browsing by Author "Maharjan, Muna"
Now showing 1 - 3 of 3
Results Per Page
Sort Options
Publication COVID-19 Diagnosed by Real-Time Reverse Transcriptase-Polymerase Chain Reaction in Nasopharyngeal Specimens of Suspected Cases in a Tertiary Care Center: A Descriptive Cross-sectional Study(Nepal Medical Association, 2021) Maharjan, Narayani; Thapa, Niresh; Magar, Bibek Pun; Maharjan, Muna; Tu, JianchengAbstract: Introduction: The emergence of severe acute respiratory syndrome coronavirus-2 pandemic is critically challenging the whole world. The real-time reverse transcriptase-polymerase chain reaction is the most widely used confirmatory test for COVID-19 detection. This study aimed to find out the prevalence of COVID-19 infection detected by gold standard reverse transcriptase-polymerase chain reaction test in a tertiary care center of Nepal. Methods: A descriptive cross-sectional study was conducted in Karnali Academy of Health Sciences from May to August 2020 after taking ethical approval from the Institutional Review Committee of Karnali Academy of Health Sciences, Jumla. Convenient sampling was used. A total of 361 participants enrolled in this study who have done real-time reverse transcriptase-polymerase chain reaction for screening of COVID-19 infection. Also, a designated questionnaire was obtained from persons with a travel history and close contact. Statistical Package for the Social Sciences software was used for the statistical analysis. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: The prevalence of COVID-19 was 167 (46.3%) (95% Confidence Interval= 41.16-51.44) by real-time reverse transcriptase-polymerase chain reaction test. Out of 361 samples, 339 (93.9%) were male and 22 (6%) were female. The highest frequency of the participants belongs to the age groups of 20-40 years. Conclusions: The findings showed a high prevalence of COVID-19 detected by reverse transcriptase-polymerase chain reaction test. Further studies are necessary to improve the precision of prevalence estimations.Publication Persistent Positivity of Reverse Transcriptase-Polymerase Chain Reaction Test among Patients with COVID-19 in Rural Teaching Hospital: A Descriptive Cross-sectional Study(Nepal Medical Association, 2021) Maharjan, Narayani; Thapa, Niresh; Magar, Bibek Pun; Maharjan, Muna; Tu, JianchengAbstract: Introduction: The persistence positivity detected for severe acute respiratory syndrome coronavirus 2 ribonucleic acid by real-time reverse transcriptase-polymerase chain reaction test in asymptomatic coronavirus disease 2019 positive patients has attracted a lot of attention. There is limited data on the duration of viral shedding. We aimed to determine the proportion of coronavirus disease patients with persistent positivity of real-time reverse transcriptase-polymerase chain reaction test in a teaching hospital of Nepal. Methods: A descriptive cross-sectional study was conducted using medical records from May to September 2020 in a teaching hospital of Nepal. The study was approved by the Institutional Review Committee of Karnali Academy of Health Sciences (Reference no 077/078/03). Convenient sampling method was used. Data was analysed by Statistical Package for the Social Sciences. Point estimate at 90% Confidence Interval was calculated along with frequency and proportion for binary data. Results: Of the total 95 cases, 9 (9.5%) cases (4.6-14.4 at 90% Confidence Interval), were repeat positive after achieving the first negative. The mean day required of achieving the last negative for the repeat positive group was 62.11±3.95, range (60-70 days). The mean time duration for the virus shedding was found to be 20.43±12.19 days (range 7-60 days) after the first positive test result. Conclusions: This study concludes that there might be a persistent positivity of the polymerase chain reaction test among patients with COVID-19. The majority of the patients were test positive for 8-14 days, and some were positive till 60-70 days.Publication Prevalence of Teenage Pregnancy in A Community Hospital of Rural Nepal: A Cross-Sectional Study(Nepal Medical Association, 2019) Maharjan, Muna; Thapa, Niresh; Maharjan, Narayani; Rai, Pabita; Pun, Prakash; Petrini, Marcia A; Yang, JiongAbstract Introduction: Teenage pregnancy is a public health concern. Maternal and neonatal health outcomes are negatively impacted in teenage pregnancy. The objective of the study is to find the prevalence of teenage pregnancy in a community hospital of rural Nepal. Methods: A descriptive cross-sectional study was conducted at Okhaldhunga Community Hospital, Okhaldhunga, Nepal. Ethical approval was taken from the Institutional Review Committee of the hospital. Data were retrieved from July 2007 to July 2017 from the hospital record books. The total of 7054 records of deliveries were reviewed from the hospital records and whole sampling was done. Subgroup analysis was done on basis of age, ethnicity, gravida, para, period of gestation, mode of delivery, maternal or neonatal complications and birth weight. Datas were entered and analyzed using Microsoft Excel. Results: The total of 7054 deliveries were conducted in ten years among which 2050 (29.06%) were teenage deliveries at the confidence interval of 95% (28.52% - 29.06%). The highest percentage of teenage delivery was found among Janajati ethnicity of 1056 (53.3%). Amongst teenage delivery, a significant tear was found in 157 (7.9%) as a maternal complication. Perinatal deaths were found in 27 (1.4%). Conclusions: The trend of teenage pregnancy remains almost same over ten years in the Okhaldhunga Community Hospital. The overall prevalence of teenage delivery is higher than the national figure. Low birth weight babies, premature delivery, perineal and cervical tears were the common complications. Further health education and awareness programs might help to reduce the teenage pregnancy rate. Keywords: Pregnancy; Rural hospital; Teenage pregnancy.