Browsing by Author "Maharjan, PB"
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Publication Appendiceal Neuroendocrine Tumor Mimicking Acute Appendicitis(Kathmandu University, 2022) Gautam, N; Makaju, R; Basnet, D; Lama, B; Maharjan, PB; Dahal, SABSTRACT Appendiceal carcinoids are the most frequent tumors arising from the appendix, comprising between 32 and 57% of all the appendiceal tumors. The gross appearance of the appendix showed perforation at the tip with 30 ml of periappendicular collection. On histopathological examination, carcinoid tumor on the tip of appendix was found with tumor cells arranged in tubules, acini and nests infiltrating the muscularis propria and sub serosa. Perineural and vascular invasion was not seen. Immunohistochemistry for Synaptophysin was positive with Ki-67 labelling index of 2%. We present a case of appendiceal neuroendocrine tumor with the chief complaint of acute appendicitis. KEY WORDS Appendectomy, Appendix, Carcinoid tumorPublication Cartilaginous Choristoma of Tonsil: A hidden clinical entity(Kathmandu University, 2021) Gautam, N; Makaju, R; Basnet, D; Lama, B; Maharjan, PBABSTRACT Choristoma is a tumor like mass which is an ectopic rest of normal tissue due to embryological developmental defect. The presence of choristoma in tonsil is extremely rare. On histopathological examination, mature hyaline cartilage were found surrounded by lymphoid follicles. We present a case of cartilaginous choristoma with the complaint of recurrent tonsillitis. KEY WORDS Cartilaginous choristoma, TonsilPublication Endometriosis of Groin Mimicking Neoplasm(Kathmandu University, 2021) Maharjan, PB; Makaju, R; Makaju, S; Dhakal, R; Lama, B; Basnet, D; Dhakal, BABSTRACT Endometriosis is principally a disease of women in active reproductive life. Although it is rare, foci of endometrial tissue may be seen in the bowel, the umbilicus, abdominal surgical scars and in the lungs. Inguinal endometriosis is challenging to the clinicians and pathologist and often diagnosed accidentally. We present a case of inguinal endometriosis mimicking neoplasm. A 40 year old woman presented with a swelling in the right inguinal region associated with cyclical pain. In view of presence of atypical cells in fine needle aspiration cytology, metastatic carcinoma was rendered as diagnosis. Histopathological examination revealed endometrial glands and stroma which was further confirmed by immunohistochemistry. Diagnosis of inguinal endometriosis is difficult and often challenging because of unusual site. The clinician must have high index of suspicion with any patient who has cyclical symptoms. A good history and physical examination can guide clinical diagnosis of endometriosis. KEY WORDS Endometriosis, Groin mass, Inguinal endometriosisPublication Hashimoto’s Thyroiditis with Squamous Metaplasia(Kathmandu University, 2024) Dahal, S; Makaju, R; Basnet, D; Dhakal, B; Shrestha, B; Maharjan, PBABSTRACT Hashimoto’s thyroiditis is an autoimmune inflammatory disease. Although rare, squamous metaplasia can be seen in Hashimoto’s thyroiditis. We present a case of 19 years female who presented with chief complaint of anterior neck swelling for three months. Thyroid Stimulating Hormone (TSH) was 3.93 mIU/L. Ultrasonography neck showed TIRADS (Thyroid Imaging Reporting and Data Systems) 5 lesion. Fine Needle Aspiration Cytology showed Papillary Thyroid Carcinoma. Histopathological examination revealed numerous lymphoid follicles of variable size with clusters of squamous metaplastic cells within the germinal centers of lymphoid follicles and surrounding fibrosis. Some cells showed nuclear clearing. Diagnosis of Hashimoto’s thyroiditis with squamous metaplasia was further confirmed by immunohistochemistry. The case presented here is rare and there are very few cases reported in literature so far. KEY WORDS Hashimoto’s thyroiditis, Squamous metaplasia, Thyroid gland