Browsing by Author "Maharjan, Rupa"
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Publication Association of Allergic Rhinitis and Thyroid Dysfunction: A cross-sectional observational study in a tertiary care center(Society of Otolaryngologists of Nepal, 2024) Kayastha, Sudin; Maharjan, Rupa; K.C., ArunAbstract: Aims and Objectives: Allergic rhinitis can be a presenting symptom of underlying thyroid dysfunction. This study aims to assess thyroid function status and to explore prevalence of underlying thyroid dysfunction in allergic rhinitis patients. Methods: This was a cross-sectional observational study carried out from July 2021 to June 2022 at Department of Otorhinolaryngology, Bir Hospital, Kathmandu, Nepal. A total of 91 allergic rhinitis patients without known thyroid disorders were included in this study. Severity and type of allergic rhinitis was categorized according to ARIA classification and their thyroid function status was assessed. Results: Out of 91 total cases, there were 47 (51.6%) males and 44 (48.4%) females. Most patients (39.56%) were in the age group 21-30 years with mean age of 30.55 years. By ARIA classification, 30.76% had mild intermittent, 19.78% had mild persistent, 30.76% had moderate-severe intermittent type and 18.68% had moderate-severe persistent type of allergic rhinitis. Thyroid function assessment revealed mean TSH value 3.57mIU/L and median TSH 2.50 mIU/L. Out of total 91 cases, 82.4% (n=75) had normal TSH, 13.2% (n=12) had high TSH, 4.4% (n=4) had low TSH. Total 16 (17.58%) patients had undiagnosed underlying thyroid dysfunction. Out of 16 cases with thyroid dysfunction, 81.25% (n=13) had moderate to severe type of allergic rhinitis. The prevalence of underlying thyroid dysfunction in allergic rhinitis patients was statistically significant (p=<0.05). Conclusion: There is some association between allergic rhinitis and underlying thyroid dysfunction. Thyroid dysfunction is more common in moderate/severe type of allergic rhinitis. Serum TSH could be a screening tool to identify underlying thyroid dysfunction in allergic rhinitis patients. Keywords: allergic rhinitis, thyroid disease, thyroid function testPublication Outcome of Intralesional Steroid Injection for Benign Vocal Cord Lesions Authors(Society of Otolaryngologists of Nepal, 2025) KC, Arun; Maharjan, Rupa; GC, AnitaAbstract: Aims and Objectives: The study aims to find out the outcome of intralesional steroid injection in benign lesions of vocal cords. Methods: This prospective, longitudinal, interventional comparative hospital-based study was conducted at Otorhinolaryngology and Head & Neck Surgery Department of Bir hospital, National Academy of Medical Sciences, Kathmandu, Nepal from March 2022 to March 2023. The pre and post treatment status documented and compared with videolaryngoscopy, voice handicap index (VHI)-10 and maximum phonation (MPT)time after 1 month. Thirty patients fulfilled the inclusion criteria. Results: Sixteen out of 30 patients showed improvement on videolaryngoscopy, mean VHI-10 reduced and mean MPT increased. The results were statistically not significant(P>0.05). Conclusion: In selected patients, those who are resistant to conventional voice therapy and those who are unfit for general anaesthesia, intralesional steroid injection is a good alternative non-surgical for the management of patients with benign vocal cord lesion. Keywords: Benign vocal cord lesion, intralesional steroid, Maximum Phonation Time, Voice Handicap Index-10