Browsing by Author "Malla, Neha"
Now showing 1 - 2 of 2
Results Per Page
Sort Options
Publication Electro-physiological Changes in the Central Nervous System by Visual Evoked Potential in Diabetic Patients(Nepal Health Research Council, 2022) Malla, Neha; Mahotra, Narayan B; Shrestha, Lava; Joshi, Sajun Narayan; Gurung, SanyuktaAbstract Background: Increasing sedentary lifestyle in today’s world has increased the prevalence of Diabetes Mellitus. Loss of vision due to diabetic retinopathy is a major public health burden. Visual evoked potential identifies the neuronal degenerative changes in chronic metabolic disorders specially Diabetes Mellitus. The study aimed at evaluating changes in visual evoked potential waves in diabetic patients. Methods: This is a cross sectional comparative study consisting of 90 participants, out of which 60 were diabetic patients and 30 were non-diabetic control group. Among diabetic patients, 30 were without retinopathy, 10 with mild non-proliferative retinopathy, 10 with moderate non-proliferative retinopathy and 10 with severe non-proliferative retinopathy. Visually evoked potential latencies and amplitudes were compared among diabetic patients and the control group and also among individuals with different grades of retinopathy. Results: Delay in P100 latency and decrease in its amplitude were statistically significant in diabetic patients. The changes in P100 latency, P100 amplitude and N75 latency were also significant in different grades of retinopathy. Conclusions: There are statistically significant changes in visually evoked potential in diabetes patients. Visual evoked potential is a useful, non-invasive investigation which can establish the central nervous system neuropathy in diabetes at an early stage of the disease. So Diabetic retinopathy can be prevented due to early detection of neuropathy by visual evoked potential test Keywords: Diabetes mellitus; diabetic retinopathy; visual evoked potentialPublication Risk Factors of Primary Dysmenorrhea among Undergraduate Students of a Medical Institution of Nepal(Central Department of Public Health, 2025) Malla, Neha; Mahotra, Narayan; Shrestha, Sushan Man; Chaudhary, SonamBackground: Primary dysmenorrhea (PD) has significant impact on life of young females. This study aimed to find various risk factors of primary dysmenorrhea and its impact on daily life. Methods: A cross-sectional study was done in 165 female undergraduate students (age ≤24 years) of Institute of Medicine by convenience sampling method. It was a questionnaire-based study. Anthropometric measurements were taken for Body Mass Index (BMI), waist circumference and waist hip ratio. Results: The study showed presence of PD in 98.2% participants among whom 20.6% had mild, 32.6% had moderate and 44.8% had severe PD. Pre-menstrual symptoms (PMS) was significantly associated with severity of PD (p <0.001, OR: 3.603, CI: 1.675-7.752). However, there was no statistically significant correlation seen with early age of menarche (p = 0.932) and family history of dysmenorrhea (p value= 0.70). No association was seen between severity of PD with BMI (p = 0.720), waist circumference (p = 0.850) and waist hip ratio (p = 0.858). Severity of PD was associated with limitations in daily activity (p value<0.001, OR:6.302, CI: 2.855-13.911), behavioral changes (p =0.001, OR: 2.638, CI: 1.186-5.864) and skipping of college (p < 0.001, OR: 10.00, CI: 2.922-34.227). Conclusions: The prevalence of primary dysmenorrhea was very high in young females. Institutional and social support system, plans and policies to support and create easy accessibility to treatment is needed. Only then young women will be able to achieve their full potential and hence social equity will be achieved.