NepMed Repository :: Browsing by Author "Marla, V"

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Relationship of Angiogenesis and Oral Squamous Cell Carcinoma
(Kathmandu University, 2015) Marla, V; Hegde, V; Shrestha, A
ABSTRACT Angiogenesis is an important aspect of a variety of physiological and pathological processes; and depends on the alteration of the balance between pro-angiogenic and anti-angiogenic factors. The role of angiogenesis in the progression and metastasis of neoplasm is a well established phenomenon. With regards to oral squamous cell carcinoma, it is a field of ongoing research and requires validation for it being used as a mode of anti-cancer therapy. This review focuses on the concept of angiogenesis, the factors associated with it, the relationship of angiogenesis with oral epithelial dysplasia and oral squamous cell carcinoma; the methods of studying angiogenesis and anti angiogenic therapy. KEY WORDS Angiogenesis, neoplasm, oral squamous cell carcinoma.