Browsing by Author "Maskey, Robin"
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Publication Autoimmune Hemolytic Anemia with Autoimmune Hypothyroidism: A Case Report(Nepal Medical Association, 2023) Karki, Prakriti; Prasai, Parikshit; Chetri, Vivek Acharya; Gautam, Arun; Maskey, RobinAbstract Autoimmune hemolytic anaemia is a relatively rare disorder caused by autoantibodies directed against self-red blood cells. Though autoimmune thyroid disease is associated with other autoimmune diseases, only a few cases of Hashimoto's thyroiditis with autoimmune hemolytic anaemia have been reported. We present a case of a 22-year-old woman, a known case of Hashimoto’s thyroiditis whose serum demonstrated antibodies against red blood cells. Blood investigations were done which showed findings suggestive of hemolytic anemia. She was managed with blood transfusion, thyroxine and steroids. Our study may guide physicians toward possible hemolytic anaemia while treating Hashimoto thyroiditis.Publication Cutaneous Manifestations of Thyroid Hormone Disorder(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2019) Sijapati, Karuna Singh; Rijal, Arpana; Agrawal, Sudha; Khadka, Dhan Keshar; Maskey, RobinAbstract: Introduction: Thyroid hormone disorder (THD), a major health problem, is associated with a wide range of diseases. One of the organs, which shows this wide range of clinical signs is the skin. Some dermatological findings may be the first symptoms of THD. Therefore, this study was planned to determine various cutaneous manifestations of THD that can be used as a diagnostic marker for THD. In Nepal due to lack of awareness, thyroid diseases may go unnoticed .So, cutaneous manifestations help in early diagnosis and treatment of THD. Objectives: To identify cutaneous manifestations of THD and to evaluate dermatological manifestations specific for THD. Materials and methods: Seventy six patients with diagnosis of THD attending endocrine clinic of Internal Medicine Department in BPKIHS, Dharan were consecutively assessed for cutaneous changes by detailed history and clinical examination. As a control group, 26 age and sex matched individuals without THD were included to assess frequency of cutaneous manifestation in normal individuals. Results: Fifty five (72.3%) cases and 4(15.4%) control had skin changes. This observation was statistically significant with OR-14.4(95% CI4.43 – 46.78) and p<0.001.Hair changes (OR-2.100, 95% CI 0.647-6.821 and p=0.210) and nail changes (OR-1.818, 95% CI 0.371-8.902 and p=0.726) had no statistically significant association with THD. Conclusion: THD may present as or be associated with many changes in skin, hair and nails. Keywords: Cutaneous changes, Hypothyroidism, HyperthyroidismPublication Pulmonary Paragonimiasis: A Case Series(Nepal Medical Association, 2023) Shah, Pratima; Sah, Rinku; Pradhan, Saugat; Bhandari,Priyanka; Baral, Ratna; Khanal, Basudha; Maskey, Robin; Bhattarai, Narayan RajAbstract Paragonimiasis contributes to significant foodborne zoonosis worldwide. The major mode of transmission in humans is by consumption of uncooked or undercooked crabs and crayfish harbouring Paragonimus metacercariae. It begins with symptoms like fever and lower respiratory involvement from a few months to a year, mimicking those of tuberculosis and leading to diagnostic delay. Here, we report two cases of paragonimiasis during a period of nine months. Both cases presented with symptoms of productive cough with rusty sputum, chest pain, along with eosinophilia, and pleural effusion and had a history of consumption of smoked crab from the local river. The diagnosis was established by microscopic demonstration of Paragonimus ova in the sputum. They were treated with praziquantel and recovered. Indeed, it is challenging to diagnose paragonimiasis due to the lack of its specific symptoms but should be considered in the differential diagnosis of eosinophilia and pleural effusion in such lung diseases.