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Browsing by Author "Mishra, AK"

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    Osteosynthesis with Locking Plate for Proximal Humerus Fracture
    (Kathmandu University, 2018) Mishra, AK
    ABSTRACT Background Approximately 5% of all fractures consists of proximal humeral fractures. In the elderly population, most of these fractures are related to osteoporosis. Internal fixation has led to unpredictable results, especially in patients with osteopenic bone and those with comminuted fractures. Objective To evaluate functional outcome and complications following proximal humerus fracture fixation using locking plate. Method This prospective observational study was conducted at Nepal Medical College and Teaching Hospital from February 2014 to June 2015. We reviewed 35 patients with proximal humerus fractures, who underwent open reduction and internal fixation with locking plate.Functional outcome was evaluated according to the Constant- Murley shoulder assessment. Result Fracture union was achieved in all cases with the mean time to union being 14.6 weeks (11-24 weeks). At the final follow up the mean constant murley score was 73.6 (48-94). There was total 8(22.85%) cases who developed complication. Conclusion Internal fixation with the locking plate for proximal humerus fractures provides stable construct with better functional outcome as it allows early shoulder mobilization. KEY WORDS Locking plate, Osteosynthesis, Proximal humerus fracture
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    Subclinical hypothyroidism in eastern Nepal: A hospital based study
    (Kathmandu University, 2010) Rohil, V; Mishra, AK; Shrewastwa, MK; Mehta, KD; Lamsal, M; Baral, N; Majhi, S
    Abstract Background: Subclinical hypothyroidism itself is associated with serious complications and also there is a known risk of subclinical hypothyroidism patients getting converted into overt disease. Objectives: The objective of the present study was to find out the prevalence of subclinical hypothyroidism in the suspected cases i.e. amongst the cases attending the thyroid laboratory at B.P. Koirala Institute of Health Sciences, Dharan, Nepal. Materials and methods: It was a retrospective cross sectional study. Data of the free T3, free T4 and TSH estimations of the year 2007 of the Thyroid lab at BPKIHS, Dharan, Nepal was analyzed. ELISA based free T3, free T4 and TSH tests in the serum had been performed in all the cases. Results: Total cases were 1714 including 24.446% males and 75.554% females. Cases with raised TSH levels were 26.021%, cases with normal TSH levels were 54.66% and cases with low TSH levels were 19.316%. Total 350 cases (20.42 %) had subclinical hypothyroid dysfunction which includes 84 (4.901 %) males and 266 (15.519%) females. And the maximum percentage of cases in either gender was between the age groups 20 -59 years. Conclusion: The prevalence of subclinical thyroid hypothyroidism amongst the suspected cases was 20.42 % which is much higher compared to the other parts of the world. The highest percentage was found in the female age group 20 – 59 years. The routine screening of the whole population is not cost effective and on the basis of the present study it is suggested that there may be routine screening of the selected populations, especially women between 20 to 59 years of age in Nepal region. The preferred screening method advised is a sensitive ELISA based TSH test. Key words: Subclinical hypothyroidism

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