Browsing by Author "Nepali, Bishal"
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Publication Hypertensive Retinopathy among Hypertensive Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study(Nepal Medical Association, 2024) Basnet, Anjila; Rai, Nilshan; Sahani, Shambhu Kumar; Pathak, Anil; Nepali, BishalAbstract Introduction: Hypertension manifests in the eyes as retinopathy, choroidopathy, and optic neuropathy of which retinopathy can be used as a predictor for systemic morbidities and mortalities. The study aims to determine the prevalence of hypertensive retinopathy among hypertensive patients visiting the outpatient Department of Ophthalmology in a tertiary care center. Methods: A descriptive cross-sectional study was conducted among hypertensive patients from 4th April to 19th November 2023 after obtaining ethical approval from the Institutional Review Committee (Reference number: 2079/80/96). A Convenience sampling method was used. The Point estimate was calculated at a 95% Confidence Interval. Results: Among 161 hypertensive patients, hypertensive retinopathy was present in 70 (43.48%) (35.82-51.14, 95% Confidence Interval). Grade I hypertensive retinopathy accounted for 35 (50%) followed by Grade II HR in 17 (24.29%), Grade III HR in 14 (20%) and Grade IV HR in 4 (5.71%) in the study participants. Conclusions: The prevalence of hypertensive retinopathy was found to be higher than other studies done in similar settings.Publication Lissencephaly with Congenital Hypothyroidism: A Case Report(Nepal Medical Association, 2022) Sahani, Shambhu Kumar; Pathak, Anil; Nepali, Bishal; Rai, NilshanAbstract Lissencephaly is a malformation of cortical development associated with deficient neuronal migration and abnormal formation of cerebral convolutions or gyri. The lissencephaly spectrum consists of agyria, pachygyria, and subcortical band heterotopia. At least 19 genes have been identified in the causation of lissencephaly and related syndrome. Lissencephaly is associated with many other congenital disorders but the association of lissencephaly with congenital hypothyroidism is rarely reported. We report a case of a 10-year-old girl having lissencephaly with congenital hypothyroidism. Early diagnosis of lissencephaly and genetic counselling can be made in suspected cases and further possible interventions can be taken. Also, regular follow-up, monitoring, and better conservative management lead to a better prognosis.