Browsing by Author "Nepali, R"
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Publication Hepatitis E induced severe myositis(Institute of Medicine, 2016) Nepali, R; Shah, DS; Sigdel, MRAbstract Hepatitis E is one of a rare cause of viral myositis in immunocompromised patients. Presentation in immunocompetent patient is even rarer. We present a case of 26-year-old female patient who presented with viral myositis secondary to hepatitis E with rhabdomyolysis with acute kidney injury with right leg foot drop due to compartment syndrome in an immunocompetent patient. Keywords: Hepatitis E, viral myositis, RhabdomyolysisPublication New onset diabetes after transplant in renal transplant recipients(Institute of Medicine, 2017) Nepali, R; Shah, DSAbstract Introduction: New onset diabetes after transplantation (NODAT) is a common complication of renal transplantation. Despite its prevalence and importance, the data on NODAT and its risk factors in Nepalese population are lacking and the incidence and risk factors for NODAT in Nepalese population who underwent renal transplantation at Tribhuvan University Teaching Hospital. Methods: All the patients who underwent living donor kidney transplantation at Tribhuvan University Teaching Hospital between August, 2008 and February, 2016 were included in this study. Patients who were diagnosed with diabetes mellitus before transplantation were excluded from the study. Patients were divided into NODAT and Non-NODAT groups. Then, risk factors were compared between the two groups. Results: A total of 350 patients who underwent living donor renal transplantation at our hospital during the study period were included. 23 patients who were diagnosed cases of Diabetes Mellitus before transplantation were excluded. In the remaining 327 cases, the incidence of NODAT was 19.57% (64 patients). Most of them (95.31%) occurred within the first 12 months’ post transplantation. The mean duration of onset of NODAT was 121.46 ± 275.58 days post transplantation. Age of the recipient greater than 45 was significantly associated with NODAT than non-NODAT patients. However, there was no statistical difference in sex between NODAT and non-NODAT patients. Conclusion: NODAT is common complication after renal transplantation. Age of recipient > 45 years is a significant risk factor for the development of NODAT. So, we have to be more vigilant in these patients Keywords: Renal transplantation, NODAT, AgePublication Pattern of Ear Diseases among Paediatric ENT Patient: An Experience from Tertiary Care Centre, Pokhara, Nepal(Nepal Paediatric Society (JNPS), 2012) Sigdel, B; Nepali, RAbstract: Introduction: Ear diseases are common in children mainly due to altered anatomy of Eustachian tube which is straighter in children as compared to that in adults. However, the cause of hearing loss in children is more varied, including the etiologies. This study was done to find out the pattern of ear diseases in paediatric age group attending ear, nose and throat OPD in a tertiary care centre in Pokhara, Nepal. Materials and Methods: This is a prospective study done in paediatric patients attending ENT OPD over a period of one year from January 2010 to January 2011. The diagnoses were made on the basis of history and clinical examination. Results were expressed in numbers and percentages. Results: Out of 1632 Pediatric ENT patients, 944 had ear diseases, 59.2% were males and 40.8% females. Wax (33.4%) was the commonest diagnosis followed by Chronic suppurative otitis media (24.3%) and Acute ottitis media (13%). Conclusion: Ear diseases are most common condition in ENT OPD among paediatric age group. Wax, CSOM and ASOM were the three most common ear diseases.Publication Pulmonary aspergillosis in a renal transplant recipient(Institute of Medicine, 2018) Nepali, R; Shah, DSAbstract Aspergilloma, one of the spectrum of pulmonary aspergillosis, is the most common and best-recognised form of pulmonary involvement by Aspergillus species. It usually develops in a pre-existing cavity in the lung secondary to tuberculosis. Here, we present a case of live non related renal transplant recipient with aspergilloma with bronchiectasis with tuberculosis who underwent left upper lobectomy with antitubercular treatment and voriconazole with complete resolution. Keywords: Renal transplant, aspergilloma, tuberculosisPublication Spectrum of neurological disorders admitted in Tribhuvan University Teaching Hospital Maharajgunj(Institute of Medicine, 2012) Gajurel, BP; Parajuli, P; Nepali, R; Oli, K KAbstract Introduction: Neurologic disorders are very common. Data on the type and burden of neurological cases either in the outpatient and inpatient settings in our country are not available. This research has been done to perform a descriptive analysis of the spectrum of neurological cases which were admitted over a period of one fiscal year in Tribhuvan University Teaching Hospital (TUTH), Maharajgunj, Kathmandu. Methods: This retrospective study included all patients who were admitted with any neurological complaints over a period of one fiscal year (Shrawan 2067 B.S. to Asar 2068 B.S.) Results: The total number of patients admitted was 1165. Out of these, 693 cases were due to neurological disorders (59.48%). The most common disorders were stroke, seizure disorder and central nervous system infections. Conclusion: A variety of neurological disorders, from very common to very rare, were admitted. Keywords: Neurologic disorders