Browsing by Author "Neupane, R"
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Publication Intrinsic Capacity of Older People in Panchkhal Municipality of Nepal: A cross-sectional study(Kathmandu University, 2024) Shrestha, L; Neupane, R; Paudel, L; Manandhar, NABSTRACT Background With the global trend of rising ageing population, health care to the elderly needs special focus as absence of disease merely does not mean that older people are healthy and have full functional ability. So, WHO introduced intrinsic capacity to define healthy ageing. Objective To find the prevalence of decline in intrinsic capacity in older people of Panchkhal Municipality. Method A community based cross-sectional observational study was conducted in 5 simple randomly selected wards of Panchkhal Municipality of Nepal. Total sample sizes of 848 data were collected using proportionate convenience sampling. Data collection techniques were interview with observation using predesigned proforma containing WHO (Integrated Care for Older People-ICOPE) tool. Result The prevalence of decline in intrinsic capacity of older people in Panchkhal Municipality was 86.9%. The decline in individual domains was visual acuity 58.0 % followed by cognition 48.9%, locomotion 48.8%, hearing ability 38.6%, vitality 38.0% and psychology 28.5%. The mean age was 71.18 ±8.769 years (60-100). The majority of older people were male 55.8%, Hindu 91.7%, had joint family 77.7% and illiterate 60.3%. There was significant moderate positive correlation of age with decline in locomotion (r=0.469, p=0.029), hearing ability (r=0.312, p=0.032), cognitive ability(r=0.209, p=0.034) and low negative correlation of age with vitality (r=-0.161, p=0.035), psychology (r=-0.130, p=0.034),visual acuity (r=-0.126, p=0.034). Conclusion There was a high prevalence of decline in intrinsic capacity of the older people from Panchkhal Municipality. Special and focused care is required for older people from the government along with implementation of WHO-Integrated Care for Older People-ICOPEtool in every healthcare setting to promote healthy ageing. KEY WORDS Capacity, Integrated care for older people (ICOPE), Intrinsic, NepalPublication Methicillin-Resistant Staphylococcus Aureus Nasal Carriers among Laboratory Technical Staff of Tertiary Hospital in Eastern Nepal(Kathmandu University, 2020) Neupane, R; Bhatt, N; Poudyal, A; Sharma, AABSTRACT Background Methicillin-resistant Staphylococcus aureus (MRSA) has been the leading cause of nosocomial and community infections worldwide. In particular, healthcare workers are at constant risk to develop MRSA carriage. There is a paucity of data regarding the epidemiology of MRSA in laboratory workers who are constantly in contact with these pathogens in almost every hospital. Objective This study was undertaken to identify the burden of MRSA nasal carriers and the antibiotic susceptibility pattern of the isolates among laboratory technical staff. Method Sterile nasal swabs were taken from 50 laboratory technical staff working in the Central and Emergency laboratory of BP Koirala Institute of Health Sciences (BPKIHS). Standard procedures were followed for isolation, identification and antibiotic sensitivity testing. Antibiotic susceptibility tests were performed using disc diffusion and growth on Oxacillin screen agar based on Clinical and Laboratory Standards Institute (CLSI) guidelines. Result Out of 50 isolates of Staphylococcus aureus, 44 (88%) were Methicillin-sensitive (MSSA) while six (12%) were Methicillin-resistant (MRSA). All 50 isolates of S. aureus were found resistant to Penicillin while all were found sensitive to Teicoplanin, Linezolid, and Levofloxacin. Only five (10%) were sensitive to Erythromycin while 49 (98%) were sensitive to both Amikacin and Gentamicin. However, none of the MRSA isolates were found sensitive to all tested antimicrobial agents. Conclusion This repertoire portrays the emergence of MRSA in laboratory workers which clearly indicates the necessity of complying with the sanitary and antibacterial guidelines and adhering to the rational use of antibiotics to prevent nosocomial infections. KEY WORDS Antibiotic resistance, Laboratory personnel, MRSA, Staphylococcus aureus