Browsing by Author "Niroula, DR"
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Publication Ethnic Variations of Blood Groups in a Medical College of Eastern Nepal(Kathmandu University, 2018) Niroula, DR; Jha, MK; Limbu, P; Pokhre, I; Yadav, SK; Mukhopadhyay, SABSTRACT Background Red blood cells contain antigens in its membrane which are inherited according to Mendelian law. ABO and Rhesus blood group systems are considered the most important blood group systems for clinical procedures, blood transfusion, organ transplantation, anthropological study and medico-legal purposes. Determination of ABO and Rhesus blood groups and its frequency distribution in a multiethnic country like Nepal is important for effective management of blood banks, safe blood transfusion services. The trend of blood groups and its ethnic distributions in the eastern part of Nepal is still unknown. Objective To find the distribution of blood groups among the subjects of different ethnic groups of eastern Nepal. Method A cross-sectional perspective study was carried out among the subjects visited in the laboratory of Nobel Medical College, Biratnagar, Nepal for a period of one year from August 1, 2015 to July 30, 2016. Result The 11,960 subjects were included in the present study, among which 5012 were males and 6948 were females. The study revealed that in ABO system, blood group distribution was 34.80% O, 28.66% A, 27.66% B and 6.89% AB. With regard to Rh blood group system, Rhesus +ve was 96.79% and Rhesus –ve was 3.21%. O blood group dominant ethnic groups were Brahmin, Bhujel, Biswakarma, Shah, Gurung, Marwari, Magar, Mahato, Mandal, Newar, Sanyasi, Tamang, Terai Brahmin and Yadav. Similarly, blood group A dominant ethnic groups were Chhetri, Dhimal, Limbu, Rai and Muslim. Howerver, blood group B was dominant in ethnic groups, namely Biswakarma, Rajput, Satar and Tharu. Conclusion The frequency distribution pattern of ABO blood group was observed as O > A> B > AB and in Rhesus system, Rhesus +ve > Rhesus –ve. Variation in blood groups distribution was observed in various ethnic groups. KEY WORDS ABO system, Blood group, Eastern Nepal, Ethnic group, Rhesus systemPublication Study on the refractive errors of school going children of Pokhara city in Nepal(Kathmandu University, 2009) Niroula, DR; Saha, CGAbstract Objectives: Refractive errors are the one of the most common visual disorders found worldwide in school going children and it is also one of the causes of blindness. It can easily be prevented, if timely proper measures are taken. In Kathmandu valley and Mechi Zone of Nepal, the distribution of refractive errors was found to be very high. No records are available from the Western part of Nepal. Considering the importance of the refractive errors the present study had been undertaken in Pokhara city. Materials and methods: Nine hundred and sixty four subjects (474 boys, 490 girls) were selected between age groups 10 to 19 years from six schools representing different region of Pokhara. After Preliminary examination: on acuity of vision with Snellen’s and Jaeger’s charts, the subjects were referred to the Manipal Teaching Hospital, Pokhara for confirmation of the refractive errors. Results: Sixty two schools children (6.43%), out of 964 had refractive errors. Myopia was found to be most common (4.05%). The refractive errors were found more in Private school children (9.29%) than Government school children (4.23%), which is statistically signi cant (P < 0.05). More boys (7.59%) were found to have suffered from refractive errors than girls (5.31%). Further, children with vegetarian diet (10.52%) had greater number of refractive errors than non-vegetarian diet children (6.17%). Conclusion: In the present study, percentage distribution of myopia was found to be higher (4.05%) than the hyperopia (1.24%) and astigmatism (1.14%). Interestingly, in the present study the refractive errors were found significantly higher in Private schools children than Government schools because the children who read in Private schools have higher socioeconomic status; spend more time in home work, watching Television and Computer as compared to government schools children. These near activities of the eyes causes stress on eyes of the children and might be one of the causes of developing myopia. Key words: Refractive errors, Nepal, Myopia, Hyperopia