Browsing by Author "Pandey, Aakriti"
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Publication Clinicopathological Profile of Dengue Infection in a Tertiary Care Centre in Nepal(Nepal Health Research Council, 2022) Thapa, Bibechan; Pandey, Aakriti; Gautum, Santosh; KC, Sajana; Chhetri, Prabha Devi; Pokhrel, Estory; Poudel, Sangeeta; Shankar, P RaviAbstract Background:Dengue is a mosquito-borne viral disease with a wide spectrum of presentations ranging from subclinical disease to severe dengue. Dengue is endemic to the Terai of Nepal. Interestingly, an increasing incidence has been reported from hilly areas like Kathmandu valley. This study explored the clinicopathological profile of dengue infection. Methods:A total of 84 serologically confirmed dengue cases from September to November 2019 at KIST Medical College were recruited in a cross-sectional study after obtaining ethical approval. Dengue was categorized as dengue without warning signs, dengue with warning signs, and severe dengue. Clinicopathological information was recorded in the proforma by reviewing patients’ records. A descriptive statistical tool and chi-square test were carried out. Results: Out of 84 patients, 76% (64) were dengue without warning signs, 21.4% (18) were dengue with warning signs and 2.4% (2) were severe dengue. About 97.6% (82) presented with fever. During the course of illness, anemia was identified in 38.1% (32), thrombocytopenia in 65.5% (55), hemoconcentration in 6% (5), and leucopenia in 82.1% (69). Similarly, elevated aspartate transaminase and alanine transaminase (ALT) was observed in 67.7% (42) and 53.2% (33) respectively. The severity of dengue on presentation to hospital was significantly associated with thrombocytopenia, leucopenia, and elevated ALT. Similarly, the severity during course of illness in hospital was significantly associated with hemoconcentration, thrombocytopenia, leucopenia, and elevated ALT. Conclusions: Most common presentation of dengue infection was fever. The most common laboratory abnormalities were leucopenia, thrombocytopenia, hemoconcentration, anemia, and elevated liver enzymes. Awareness of these clinical and laboratory parameters is important for the prompt diagnosis, severity estimation, and overall management of dengue infection. Keywords: Biochemical; dengue; hematological; Nepal; serologicalPublication Sexual Intercourse during Pregnancy among Postpartum Women Admitted to the Department of Obstetrics in a Tertiary Care Centre(Nepal Medical Association, 2023) Bibechan Thapa,; Pradhan, Smrity Maskey; Maharjan, Meenu; Pandey, Aakriti; Sen, Kamana; Karki, Shreyasi; Pudasaini, Prajwal; Tiwari, AnuAbstract Introduction: Pregnancy is a time when women's bodies and minds go through a lot of changes. Sexuality is an important part of a woman's health and well-being, and it often changes during pregnancy. Most women admit that their libido changes in some way during pregnancy. However, the sexuality of a pregnant woman is very individual and influenced by a variety of different factors. This is a very important topic that is often taboo, especially in a male-dominated society, and it needs to be explored more. The aim of this study was to find out the prevalence of sexual intercourse among postpartum women admitted to the Department of Obstetrics in a tertiary care centre. Methods: A descriptive cross-sectional study was conducted among postpartum women admitted to a tertiary care centre after taking ethical approval from the Institutional Review Committee. The study was carried out from 1 January 2021 to 30 December 2021. Convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval. Results: Among 97 pregnant women admitted to the Department of Obstetrics, the prevalence of sexual intercourse was 36 (37.11%) (27.50-46.72, 95% Confidence Interval). A total of 34 (94.44%) were sexually active in the first trimester while 13 (36.11%) and 4 (11.11%) were sexually active in the second trimester and third trimester respectively. Conclusions: The prevalence of sexual intercourse during pregnancy was lower than other studies done in similar settings