Browsing by Author "Pandit, Shashwata Raj"
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Publication Cutaneous Manifestations in Obese Patients Attending Outpatient Department of a Tertiary Care Hospital(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2025) Pandit, Shashwata Raj; Neupane, SaraswotiAbstract: Introduction: Obesity can have many effects on skin physiology. It is involved in dermatologic diseases like acanthosis nigricans, acrochordons, keratosis pilaris, hirsutism, and striae distensae. Objectives: To determine the proportion of various cutaneous manifestations in obese patients. Materials and Methods: This cross-sectional study was conducted at the Outpatient Department of Dermatology in a tertiary care hospital. Any patients over 18 years old with a BMI greater than or equal to 30 kg/m2 attending the dermatology OPD were included. The history-taking and examination were done, and the preformed proforma was completed. Statistical analysis was done using Microsoft Excel 2016 and SPSS Version 20.0 for Windows. Results: Our study included 226 patients. The mean age of patients in our study was 37.45± 13.60 years. There were more females than males in our study. The mean BMI of patients in our study was 32.09±1.81. According to BMI, most patients fell into grade I obesity (89.4%), followed by grade II obesity with 10.6%, and there were no patients with grade III obesity. Acrochordons was the most common dermatosis seen in the study, followed by acanthosis nigricans. The dermatoses that showed a statistically significant relationship with obesity grades were plantar hyperkeratosis (P = 0.001) and lymphoedema (P = 0.0036). Conclusion: Skin diseases are so common among obese patients that they can be considered a marker for obesity.Publication Pseudoxanthoma Elasticum a Rare Genetic Disorder : A Case Report(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2024) Pandit, Shashwata Raj; Khadka, Anupa; Jha, Ayush; Shrestha, Rima; Shrestha, Ravina BadeAbstract: Pseudoxanthoma elasticum (PXE) is a rare hereditary condition marked by the accumulation of fragmented and calcified elastic fibers in the body's tissues, leading to skin, vascular, and ocular involvement. In clinical practice, the most prevalent and typically earliest indication of PXE is observed through skin manifestations, which include laxity and the presence of yellowish papules and plaques. Here we report a case of a 40-year-old woman from Nepal presenting with yellowish multiple papules and plaque around the neck and axilla for 20 years, slowly increasing in size and number. A skin biopsy revealed fragmented eosinophilic elastic fibers in the dermis, consistent with PXE. Echocardiography, slit lamp, and indirect ophthalmoscopic examination were done.