Browsing by Author "Pant, P"
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Publication A Fatal Presentation of Dermatomyositis(Kathmandu University, 2012) Khatiwoda, P; Kayastha, SR; Khatiwada, P; Giri, A; Baral, S; Bista, D; Pant, PABSTRACT Dermatomyositis (DM) is an autoimmune disease that mainly affects the skin, muscle, and lung. The pathogenesis of skin inflammation in DM is not well understood. We present a 40-year-old male who presented with four months history of generalized skin lesion, pain and weakness. He had elevated transaminases with detectable muscle weakness. This case highlights the need to consider dermatomyositis with skin lesion and weakness; and the use of aggressive immunosuppressive therapies due to its associated vasculopathies. KEY WORDS Cutaneous lesions, dermatomyositis, idiopathic, myopathy, vasculitisPublication Pulmonary Azygous Lobe-An Anatomical Variant(Kathmandu University, 2014) Sieber, W; Karcara, N; Pant, PABSTRACT Pulmonary azygous lobe is one of the common lung malformations. There is only few article about azygous lobe. Its a small accessory lobe sometimes found on the upper part of the right lung, separated from the rest of the upper lobe by a deep groove lodging the ayzygous vein. This reports decribes the presence of azygous lobe, a rare anatomical variant, encounted during chest x-ray discussion. We describe here the anatomical basis and the clinical significance of azygous lobe. KEY WORDS Anatomical variants, azygous lobe, significancePublication Understanding of Tobacco and Lung Cancer Among Medical Students in Kathmandu University School of Medical Sciences (KUSMS)(Kathmandu University, 2012) Khatiwada, P; Kayastha, SR; Pant, P; Khanal, KR; Giri, A; Khatiwoda, P; Mali, AABSTRACT Background Often, lung cancer is diagnosed at terminal stages. Poor awareness about the symptoms or risk factors of lung cancer among medics may be one of the factors for delayed diagnosis. Objective We explored the knowledge of medical students and their behavior with the patients of lung cancer. Method Qualitative and quantitative approaches were used for data collection from 153 medical student of Kathmandu University School of Medical Sciences from December 2011 to May 2012. Results Among the results, eighty-nine students had over 80% knowledge of the 14 cancer warning signs, among them 83% knew the nine risk factors for lung cancer. Twenty-three students told lung cancer can be hereditary. Sixty five percent of all participants believed that lung cancer can be detected at early stage; of them 81% told that it can be treated. About 24% of the total students were current or ex- smokers and about half of them believed that lung cancer does not occur in light smokers. Only 10% have heard of Framework Convention on Tobacco Control in Nepal. Conclusion Study finds that all medical students who know about any cancers may not necessarily have knowledge about lung cancers. Their perception about the cause of lung cancer may be influenced by their smoking behavior and there was little knowledge of public health measures for smoking control. Awareness about national policies needs to be increased. KEY WORDS knowledge, lung neoplasm, medical education, smoking, tobaccoPublication Unusual Site of Metastasis of Bronchogenic Carcinoma(Kathmandu University, 2010) Pant, P; Sedhain, A; D’Souza; Renuka, BGABSTRACT Metastasis of bronchogenic carcinoma to the chest wall and axillary lymphnodes is a rare occurence. This study reports the case of a patient presenting with chest wall swelling as initial symptom which on evaluation was found to be a lymphnode metastasis. The patient also had axillary lymphnode metastasis on the same side as the chest swelling with a contralateral pleural effusion. Here, we discuss the pathways and possible mechanisms of contra lateral axillary and chest wall lymphnode involvement without ispilateral nodal involvement in bronchogenic carcinoma. Key Words bronchogenic carcinoma, contralateral metastasis, axillary lymphnodes, chest wall massPublication Upper gastro-intestinal bleeding: Aetiology and demographic profile based on endoscopic examination at Dhulikhel Hospital, Kathmandu University Hospital(Kathmandu University, 2010) Gurung, RB; Joshi, G; Gautam, N; Pant, P; Pokhrel, B; Koju, R; Bedi, TRSAbstract Background: The upper gastrointestinal bleeding (UGIB) is defined as bleeding within the intraluminal gastrointestinal tract from any location between the upper oesophagus to the duodenum at the ligament of Treitz. It is one of the important medical emergencies worldwide. Objective: The objective of this study is to study the aetiology of upper gastrointestinal bleeding based on endoscopic examination findings in patients of various demographic characteristics. Materials and methods: This is a retrospective observational study. The endoscopic record book from 2007 January to 2009 October was reviewed for all the cases who underwent oesophago-gastro-duodenoscopic examination for upper GI bleeding. The clinico-epidemiological data of all the patients was reviewed and analyzed in concert with the aetiology of bleeding. Results: A total of 90 patients (58 males, 32 females; mean age 45.32+ 18.47 years) of upper gastrointestinal bleeding was studied and analyzed in terms of aetiology of bleeding and demographic profile. Among the ethnic groups, Aryan 46 (51%) was the most common ethnic group to have upper GI bleeding followed by Newars 24 (27%), Mongolians 16 (18%), Dalits 3 (3%) and others 1 (1%). Out of 90 patients, 47( 52.2%) cases was less than 45 years of age, 30(33.3%) of 46 to 65 age ; and 13(14.4 %) more than 65 years of age. Gastric ulcer 23(25.6%) was the most common endoscopic finding, followed by oesophageal varices 14 (15.6%), acute erosive/haemorrhagic gastropathy 11 (12.2%), duodenal ulcer 9(10%), growth 7(7.8%), vascular lesions 3(3.3%), Mallory-Weiss tear 1(1.1%), fundal varices 1(1.1%) and, no cause was identified in 21(23.3%) cases. The peptic ulcer bleeding was the most common finding in Aryan 22(47.9%), whereas oesophageal varices and growth were more common in Newar 7(29.2%) and 3 (12.5%) respectively. Conclusion: Peptic ulcer disease is the most common cause of upper GI bleeding which was most commonly found in Aryan population; followed by oesophageal varices and growth as second and third most common causes and were more prevalent in Newar and Mongolian people. Key words: Endoscopy, Peptic ulcer disease, Upper GI bleeding, VaricesPublication Young people’s knowledge, attitude, and behaviour on STI/HIV/AIDS in the context of Nepal: A systematic review(Kathmandu University, 2009) Upreti, D; Regmi, P; Pant, P; Simkhada, PAbstract Background: Sexual and reproductive health of young people has become a major health problem in recent decades. Recent and rapidly increasing Human Immune Deficiency Virus (HIV) rates show an urgent need for Sexually Transmitted Infections (STIs) and HIV prevention interventions in Nepal. Objectives: This paper attempts to assess knowledge, attitude and behaviour on STIs/HIV/AIDS in the context of young peoples of Nepal. Materials and methods: A systematic review based on the available literature was carried out including both qualitative and quantitative studies. Results: Our findings indicate that the overall knowledge regarding STIs and HIV/AIDS is high although the level of knowledge seems to differ according to education, gender, and area of residence. Knowledge about condoms was also very high but practice of correct and consistent use in premarital and extramarital sexual relations with non-regular partners seems to be lower. The overall sexual behaviour among young people is unsafe. Conclusion: This suggests that young people’s sexual and reproductive health issues need to be further addressed and explored in order to promote safer and responsible sexual behaviour. Key words: Attitude, Behaviour, HIV/AIDS, Knowledge, Nepal, STIs, Systematic Review, Young people