Browsing by Author "Paudel, Ashok"
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Publication Chronic Obstructive Pulmonary Disease among Patients Visiting the Emergency Department of a Tertiary Care Centre: A Descriptive Cross- sectional Study(Nepal Medical Association, 2022) Thakali, Kabir; Lamsal, Dinesh; Thapa, Sabitra; Karki, Iswor; Paudel, Ashok; Gautam, Manish K.C.Abstract Introduction: Chronic obstructive pulmonary disease is characterised by persistent airflow limitation which is usually progressive and is the primary global cause of morbidity and mortality. It is the third leading cause of Years Lived with Disability, the second most common cause of death after ischemic heart disease, and the fourth most common cause of premature death. The aim of this study was to find out the prevalence of chronic obstructive pulmonary disease among patients visiting the emergency department of a tertiary care centre. Methods: A descriptive cross-sectional study was done in the Department of Emergency Medicine of a tertiary care centre from 4 July 2022 to 11 July 2022. Ethical approval was obtained from the Institutional Review Committee (Reference number: 24). Data from 348 patients were collected from the hospital records. Convenience sampling method was used. Point estimate and 95% Confidence Interval were calculated. Results: Among 348 patients visiting the emergency department, 23 (6.60%) (6.57-6.63%, 95% Confidence Interval) had chronic obstructive pulmonary disease. The mean age of these patients was 73.50±2.76 years. Conclusions: The prevalence of chronic obstructive pulmonary disease was lower than in the previous studies done in similar settings. The study could provide a general idea of the burden of the disease.Publication Polycythemia among Patients with Chronic Obstructive Pulmonary Disease Admitted to the Department of Medicine in a Tertiary Care Center: A Descriptive Cross-sectional Study(Nepal Medical Association, 2023) Thapa, Krishna Bahadur; Paudel, Ashok; Dhital, Sujan; Shrestha, Abhash; Ojha, Liladhar; Shrestha, AkarshaAbstract Introduction: Chronic obstructive pulmonary disease is a preventable and treatable disease marked by persistent airflow limitation. Abnormal rise of haemoglobin and/or hematocrit in peripheral blood is known as polycythemia which includes increased haemoglobin: greater than 16.5 g/dl in men or greater than 16.0 g/dl in women and increased hematocrit: >49% for men and >48% for women. Men, current smoking, impaired carbon monoxide diffusing capacity, severe hypoxemia, and high altitude living are risk factors associated with an increased risk for secondary polycythemia. Polycythemia contributes to the development of cor-pulmonale and pulmonary hypertension, which are linked to poor prognosis. This study aimed to find out the prevalence of polycythemia among patients with chronic obstructive pulmonary disease admitted to the department of medicine in a tertiary care centre. Methods: A descriptive cross-sectional study was conducted among patients with chronic obstructive pulmonary disease admitted to the Department of Medicine in a tertiary care centre after receiving ethical approval from Institutional Review Committee (Reference number: 153/079/080). The study was conducted from 15 September 2022 to 2 December 2022. Data were collected from the hospital records. A convenience sampling method was used. Point estimate and 95% Confidence Interval were calculated. Results: Among 185 patients, Polycythemia was seen in 8 (4.32%) (1.39-7.25, 95% Confidence Interval) patients among which 7 (87.5%) were females and 1 (12.5%) were male. Conclusions: The prevalence of polycythemia was lower compared to other similar studies done in similar settings.