Browsing by Author "Phuyal, Anjit"
Now showing 1 - 2 of 2
Results Per Page
Sort Options
Publication Clinicopathological Outcome of Early and Late Onset Renal Cell Carcinoma: An Observational Study(Institute of Medicine, Tribhuvan University, 2024) Pandit, Durga; Phuyal, Anjit; Gyawali, Milan; Guragain, Bipin; Parajuli, Purushottam; Pradhan, Manish Man; Poudyal, Sujeet; Chapagain, Suman; Luitel, Bhojraj; Chalise, Pawan Raj; Sharma, Uttam Kumar; Gyawali, PremAbstract: Introduction Renal cell carcinoma (RCC) is considered a disease of old age and is typically found in the 6th-8th decade of life. The diagnosis of RCC is increasing more rapidly in younger age patients. This study was conducted to evaluate the clinicopathological pattern and outcome of early onset RCC and compare them with the older age group patients. Methods This was a single center observational study. All the patients undergoing radical or partial nephrectomy during the period of November 2019 to October 2022 for renal masses and whose final histopathology report showed RCC were included in the study. Clinicopathological patterns and outcome were compared between the two age groups. Results Among 47 patients, 17 (36.2%) patients were at or below the age of ≤46 years and 30 (63.8%) patients in older age group. There was significant difference in male (29): female (18) ratio between the two age groups (p < 0.005). Younger age patients (≤46 yrs) had higher stage of disease at presentation compared with the older age (>46 yrs) patients [tumor extension into major veins and perinephric tissue (T3) and above 26 vs 21] and they had significantly higher mortality rate (29.4% vs 3.3%, p =0.01). Conclusion Patients aged ≤46 years of age were more frequently affected by RCC with female predominance. Younger age group had higher stage of disease at presentation with higher mortality in comparison to older age group.Publication Periprocedural Antibiotic Prophylaxis Practice during Diagnostic Cystoscopy: An Observational Study(Institute of Medicine, Tribhuvan University, 2024) Phuyal, Anjit; Chapagain, Suman; Chalise, Pawan Raj; Luitel, Bhojraj; Poudyal, Sujeet; Gyawali, Prem RajAbstract: Introduction Both American and European guidelines recommend against routine use of antibiotics prophylaxis in routine cystoscopy. But studies have shown that antibiotics use during cystoscopy is discordant from available guideline recommendations even in Europe and America. This study aims to identify prophylactic antibiotic uses pattern of Nepalese Urologists and measure adherence to guidelines. Methods An online questionnaire based self-reported survey was conducted among the practicing urologists of Nepal, who were full members of Nepalese Association of Urologists. The questionnaires in Google Forms were sent via emails to 96 urologists of Nepal. Fully completed questionnaires were analyzed. Results Out of 96 emails 58 fully filled questionnaires were received and analyzed. Routine prophylactic antibiotics prescription before cystoscopy was reported by 43 (74.1%) urologists. Availability of Antibiotic Stewardship/Antimicrobial Stewardship team at their workplace was reported by 31 (53.4%) urologists and 19 (32.8%) urologists reported of having Standard Operating Procedure regarding peri-procedural antibiotic prophylaxis at their workplace. No verification of the answers were done and reported as received. Conclusion Peri-procedural antibiotic prophylaxis practice during cystoscopy was highly prevalent.