Browsing by Author "Pradhan, Sushmita"
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Publication A Rare Case of Idiopathic Atrophoderma of Pasini and Pierini(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2023) Xiao, Hui; Pradhan, Sushmita; Yang, Xingchun; Liu, Jiaxiu; Zhu, TangyouAbstract: Idiopathic atrophoderma of Pasini and Pierini (IAPP) is a rare pigmented atrophic cutaneous disease. Here, we report a case of a 27-year-old woman who presented with asymptomatic brown patches on her upper back for one year. There was no prior history of swelling or induration of the lesions. Physical examination showed atrophic patches with clear boundaries, consistent with snow footprints or cliff-drop-like changes on edge. Dermoscopy revealed numerous bare linear, branched blood vessels and perifollicular brownish areas, which differs from only one previously reported IAPP. Biopsy showed perivascular mononuclear cells infiltrating the dermis and reduced elastic fibers in the upper and middle dermis. Typical clinical findings of “footprints in the snow” appearance and dermoscopy could combine for a definite diagnosis aiding in differentiating from morphea presenting with whitish structureless and hairless areas. This case report might stimulate clinicians to diagnose such a rare disease in patients with similar lesions to avoid unnecessary treatment.Publication Clinicoepidemiological Study of Cutaneous Leishmaniasis: A Hospital Based Study(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2023) Pradhan, Sushmita; Shrestha, Shristee; Khadka, Damber; Parajuli, Niraj; Baral, Suwash; Tsuruta, DaisukeAbstract: Introduction: Cutaneous leishmaniasis is a tropical disease transmitted by the bite of an intracellular parasite infected sandfly. Visceral leishmaniasis is common in Nepal. However, cutaneous leishmaniasis remains rare with only limited number of cases documented in Nepal. Objectives: To describe the clinical and epidemiological distribution of cutaneous leishmaniasis in Karnali province of Nepal. Materials and Methods: All cases clinically diagnosed from direct microscopic Giemsa-stain smears, histopathology or fine needle aspiration cytology as cutaneous leishmaniasis were enrolled in the study for one year. Demographic data and clinical details were recorded on a printed proforma. Statistical analysis was done using STATA/SE version 15.0 for MacBook. Results: Only 46 cases with age ranging from 2 to 75 years were included in the study. Mean age was 23±2.45 years. Majority of cases below 20 years (47.83%) were infected. Male to female ratio was 0.70:1. Mean duration of the disease was 4.96±0.47 months. Single lesions (73.91%) were mostly present. Single lesions were particularly presented on the face (73.53%). Cutaneous leishmaniasis (95.65%) outnumbered mucocutaneous one on lips (4.35%). Ulcerative-papulonodular type lesions (58.70%) were mostly presented in the cases. Kalikot district (56.52%) had the majority of cutaneous leishmaniasis cases in Karnali province. Majority of the cases presented during the months of February, March, April, August, November, and December (65.22%). Conclusion: The study concluded that the increase in cutaneous leishmaniasis is alarming in the Kalikot district of Karnali province in Nepal. The result of this study would continue contributing to the existing data in the literature and encourage early diagnosis and treatment of cutaneous leishmaniasis.Publication Multifocal Infantile Hemangiomas Treated by Oral Itraconazole: A Case Report(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Wu, Wei; Pradhan, Sushmita; Ran, Xin; Cai, Yanxia; Xie, Jinying; Zhou, Shunting; Ran, YupingAbstract: We describe a case of a 2-month-old girl presented with more than 60 papules and nodules of hemangiomas involving the skin of the sclera, endocanthion, lower lip, and labium majus pudenda without visceral hemangiomas and laboratory abnormality. A skin biopsy showed numerous scattered, clearly limited, irregular cellular lobules in the dermis circumvoluted into capillaries comprising incomplete vessel walls, which was consistent with a diagnosis of multifocal cutaneous infantile hemangioma. Oral treatment with itraconazole (5mg/kg/day) for 26 weeks resulted in predominantly involution of the skin hemangiomas. We would like to report a rare case of multifocal cutaneous infantile hemangioma, successfully treated with oral itraconazole.Publication Standardizing Editorial Process Towards Quality(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Thapa, Deeptara Pathak; Pradhan, SushmitaAbstract: A quality journal depends upon well-organized, structured, and efficient editorial activity. In addition, it is also determined by robust peer-review, pellucid focus and scope of the journal, amiability to authors, and open access for scholarly exchange of scientific research for paramount researchers worldwide.