Browsing by Author "Pudasaini, Prajwal"
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Publication An Observational Study to Evaluate Quality of Life in Patients with Melasma in A Tertiary Level Hospital of Pokhara(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2021) Pudasaini, Prajwal; Neupane, SaraswotiAbstract: Introduction: Melasma is an acquired hyper melanosis that becomes more pronounced after sun exposure. Centro facial which is the commonest pattern followed by Malar and Mandibular are three clinical patterns of Melasma. Genetic influences, exposure to UV radiation, pregnancy, hormonal therapies, contribute to the pathogenesis of melasma. Melasma may considerably have significant effect on quality of life of patients. Objectives: The present study was conducted to evaluate the effects of melasma in quality of life (QoL) in the form of DLQI (Dermatology Life Quality Index) and severity of melasma according to Melasma Area and Severity Index (MASI). Materials and Methods: This is a hospital based cross-sectional prospective study conducted in 193 Melasma patients in the Department of Dermatology, Venereology and Leprology, Gandaki Medical College and Teaching Hospital, Pokhara from November 2018 to November 2019. MASI score was calculated and the patients were provided with a Nepali version of DLQI to fill up. Results: This study included 193 patients. Mean age of patients with melasma was 29.4 ± 8.5 years with maximum reported age of 59 years. The Mean age of onset of disease was 26.5 years. The Mean age of onset of disease had little impact on DLQI. The mean DLQI score was 10.9 ± 5.9, thus indicating “very large effect on patient’s life”. The mean MASI score was 6.6 ± 5.2. It was found that there was no correlation between severity of disease and DLQI scores (p=0.317) Conclusion: Melasma commonly affected females during second and third decades of life. It had a very large effect on patient’s life as assessed by DLQI. Keywords: Melanosis, Quality of Life, Severity of Illness Index, Ultraviolet RaysPublication Cutaneous Manifestations of Covid-19 in Nepal: A Series of Case Reports(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Pudasaini, Prajwal; Gurung, Gyaltsen; Paudel, Asmita; Paudel, SushilAbstract: Coronavirus Disease 2019 (COVID-19) is an illness caused by SARS-CoV-2. Case series of large population on cutaneous manifestations of COVID-19 are yet to be reported from Nepal. Among the cases in our study, onset of urticarial rash prior to onset of fever and systemic symptoms can be very important in preventing the chain of transmission of COVID-19 infection. Knowledge among medical practitioners of varied cutaneous features of COVID-19 can lead to testing COVID-19 in these cases and an early diagnosis.Publication Papular Elastorrhexis: A Case Report of Rare Connective Tissue Naevus(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2021) Pudasaini, Prajwal; Pudasaini, Prashant; Bhatta, RabiAbstract: Papular Elastorrhexis (PE) is a connective tissue naevus that presents with non-follicular, yellow or white oval papules(1-5mm), mostly on the proximal extremities and the trunk. It is diagnosed with good clinical acumen and histologically with fragmented or decreased dermal elastic fibers. PE is difficult for clinicians to diagnose because of the rarity of the disease and non-specific presentation. Here we report a rare case of PE.Publication Quality of Life in Nepalese Patients with Non-Scarring Alopecia: A Cross-Sectional Observational Study at a Tertiary Center(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Paudel, Sushil; Pudasaini, Prajwal; Parajuli, NirajAbstract: Introduction: Alopecia is a dermatological condition characterized by the loss or reduction of hair. Alopecia areata and androgenetic alopecia are fairly common hair disorders. Hair loss causes a significant impact in person’s life which may lead to loss of self-confidence and distorted body image. Materials and Methods: All consenting patients with alopecia areata and androgenetic alopecia, presenting to the out-patient department from September 2020 to August 2021 were enrolled based on convenience sampling method in this observational study. Ethical clearance was obtained from the ethical review committee of same institute (IRC protocol no.9/2021). All patients completed the Nepali Dermatology Life Quality Index questionnaire. Statistical Package for Social Studies version 25 was used for statistical analysis. Mean scores between groups were compared with Mann-Whitney U test. Results: Out of 142 patients, there were 79 (55.6%) males and 63 (44.4%) females. There were 48 (33.8%) patients of alopecia areata while ninety-four (66.2%) had androgenetic alopecia. The mean total of Dermatology Life Quality Index score was 8.16 (±6.126). Mean score of females was 9.16±5.858 which was significantly higher than that of males 7.37±6.258 (p<0.05) and the score of the androgenetic patients (9.45±6.094) was significantly higher than that of areata patients (5.65±5.417) (p<0.001). All sub-domains of the questionnaire were impaired more in female. Increasing duration of the disease and hair loss in any first degree relative increased the impairment in quality of life significantly. Conclusion: The quality of life in females were more affected as compared to males in both kinds of hair loss. However, patients with androgenetic alopecia had a greater impairment than patients with alopecia areata in our population.Publication Quality Of Life in Patients with Non-Genital Warts: A Cross-Sectional Study using Dermatology Life Quality Index (DLQI) Questionnaire(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Paudel, Sushil; Pudasaini, Prajwal; Kafle, Monique; Acharya, InduAbstract: Introduction: Warts are one of the commonest causes for the dermatology outpatient department visits. These are caused by the Human Papilloma Viruses (HPV). Sometime warts can cause significant embarrassment and consequently impair the quality of life. Materials and Methods: All consenting patients with non-genital warts presenting to the clinic from September 2020 to February 2021 were enrolled in this observational study. Clinical evaluation for non-genital warts, sites involved and patient demographics was recorded. All participants were asked to complete the Nepali Dermatology Life Quality Index (DLQI) questionnaire. Results: Out of total 80 patients, 55 (68.8%) were males. The mean age of the study population was 23.86±7.42 years, mean duration was 21.98±26.69 months and the mean DLQI score was 8.0±5.15. The embarrassment or self- consciousness was the most prominent psychological aspect in the patients with the warts, followed closely by the difficulty in carrying out daily household activities. All items measured in DLQI were more impaired in women than in men. Clothing habits and sexual functions were affected based on the site of involvement with the warts. Shorter duration of disease had higher negative impact in the quality of life. Conclusion: Patients with warts had moderate impact in their quality of life. Females seem to be affected more due to their warts. Shorter duration of disease had higher negative impact in cases of warts.Publication Scrub Typhus in Western Nepal: A Series of Case Reports(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2020) Pudasaini, Prajwal; Ranjit, Annu; Neupane, SaraswotiAbstract: Scrub typhus, a mite borne infectious disease which is transmitted to humans by bite of trombiculid mite. An eschar, which is a characteristic necrotic skin lesion, is formed at the site of bite. Systemic spread via the hematogenous and lymphatic routes occur and the infected people develop fever, cutaneous rash, myalgia, and lymphadenopathy. Diagnosis of scrub typhus is often difficult because of vast variability and non-specific presentation of the disease. Scrub typhus has been poorly reported from Kaski district. Here we report series of five cases of scrub typhus from Kaski distrist of Western Nepal. Keywords: Nepal, Orientia tsutsugamushi, Scrub Typhus, TrombiculidaePublication Sexual Intercourse during Pregnancy among Postpartum Women Admitted to the Department of Obstetrics in a Tertiary Care Centre(Nepal Medical Association, 2023) Bibechan Thapa,; Pradhan, Smrity Maskey; Maharjan, Meenu; Pandey, Aakriti; Sen, Kamana; Karki, Shreyasi; Pudasaini, Prajwal; Tiwari, AnuAbstract Introduction: Pregnancy is a time when women's bodies and minds go through a lot of changes. Sexuality is an important part of a woman's health and well-being, and it often changes during pregnancy. Most women admit that their libido changes in some way during pregnancy. However, the sexuality of a pregnant woman is very individual and influenced by a variety of different factors. This is a very important topic that is often taboo, especially in a male-dominated society, and it needs to be explored more. The aim of this study was to find out the prevalence of sexual intercourse among postpartum women admitted to the Department of Obstetrics in a tertiary care centre. Methods: A descriptive cross-sectional study was conducted among postpartum women admitted to a tertiary care centre after taking ethical approval from the Institutional Review Committee. The study was carried out from 1 January 2021 to 30 December 2021. Convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval. Results: Among 97 pregnant women admitted to the Department of Obstetrics, the prevalence of sexual intercourse was 36 (37.11%) (27.50-46.72, 95% Confidence Interval). A total of 34 (94.44%) were sexually active in the first trimester while 13 (36.11%) and 4 (11.11%) were sexually active in the second trimester and third trimester respectively. Conclusions: The prevalence of sexual intercourse during pregnancy was lower than other studies done in similar settings