NepMed Repository :: Browsing by Author "Pun, Sunita"

Browsing by Author "Pun, Sunita"

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Effect of Interpregnancy Interval on Pregnancy Outcome in a Tertiary Care Centre: A Descriptive Cross-sectional Study
(Nepal Medical Association, 2024) Koirala, Poonam; Koirala, Ishita; Pun, Sunita; Karna, Shweta
Abstract Introduction: Interpregnancy interval has a major impact on the maternal and fetal health worldwide. Women with short interpregnancy interval show higher rates of low birth weight and preterm babies. So this study aimed to study the effect of interpregnancy interval on pregnancy outcomes. Methods: This descriptive cross-sectional study was conducted in the Department of Obstetrics and Gynaecology of a tertiary care center after taking ethical approval from Institutional Review Committee (Reference number:229/080/081(6-11)E2). Data from September 1st, 2023 to January 30th, 2024 was collected. All multigravida women with singleton pregnancy after 28 weeks of gestation who delivered in our hospital with previous birth were enrolled in the study. Point estimate and 95% Confidence Interval were calculated. The data was entered and analyzed using IBM SPSS Statistics version 26.0 Results: Among the women, 31 (3.57%) women had short interpregnancy interval ≤18 months whereas 836 (96.43%) had interpregnancy interval of >18 months. The mean age of the women was 28 years. Previous cesarean section was common indication of cesarean section 27 (87.09%) among women with short interpregnancy interval. These women had higher rates of preterm and low birth weight babies 11(35.58%) and 15(48.38%). Conclusions: Women with short interpregnancy interval ≤18 months had higher preterm births and low birth weight babies. Pregnancy induced hypertension, hypothyroidism and gestational diabetes were increased in women with interpregnancy interval of >18 months.
Induced Abortion: A Risk Factor for Adenomyosis
(Nepal Health Research Council, 2022) Pun, Sunita
Abstract Background: Abortion, the medical and surgical termination of a pregnancy,is becoming a more common medical procedure among women in Nepal. Adenomyosis is one of the common gynecological problems among women of reproductive age. However, little is known about the relationship between abortion and adenomyosis. Therefore, our study aims to explorerisk factor for adenomyosis in among women who havehadabortions. Methods: A comparative study was carried out among women who visited at thedepartment of Obstetrics and Gynecologyof the Tribhuvan University of Teaching Hospital, Kathmandu, between 13th April 2016 to 14th July 2017. Adenomyosis were confirmed through histological examination after hysterectomy. Data wereanalyzed by using Statistical Package for Social Sciences (SPSS software)21.0 version. Odd ratio with their 95% confidence interval and P-value were calculated and analyzed. A P-value equal or below 0.05 was considered as statistically significant. Results: Of the total 255 women, 85were confirmed adenomyosisby histological examination. Of the 85 cases, 39% (33/85) had a history of abortion, while only 25 % (44/170)women had abortion among non-adenomyosis group. Overall, women who had abortion were1.8 timesmore likely to have adenomyosis (95% CI 1.04- 3.17, P value=0.03) compared to women who had no history of abortion. Women with surgical abortions were 2.5 times more likely to develop adenomyosis (95% CI- 1.03- 6.21, P value=0.03) compared towomen with no abortion history. Conclusions: This study found that women,who had abortions,aremore likely to have been diagnosed with adenomyosis compared to women without abortions.Further studies, however, need to be carried out in order toextend findings of this study. Keywords: Abortion; adenomyosis; risk factors
Induced Abortion: A Risk Factor for Adenomyosis
(Nepal Health Research Council, 2022) Pun, Sunita
Abstract Background: Abortion, the medical and surgical termination of a pregnancy,is becoming a more common medical procedure among women in Nepal. Adenomyosis is one of the common gynecological problems among women of reproductive age. However, little is known about the relationship between abortion and adenomyosis. Therefore, our study aims to explorerisk factor for adenomyosis in among women who havehadabortions. Methods: A comparative study was carried out among women who visited at thedepartment of Obstetrics and Gynecologyof the Tribhuvan University of Teaching Hospital, Kathmandu, between 13th April 2016 to 14th July 2017. Adenomyosis were confirmed through histological examination after hysterectomy. Data wereanalyzed by using Statistical Package for Social Sciences (SPSS software)21.0 version. Odd ratio with their 95% confidence interval and P-value were calculated and analyzed. A P-value equal or below 0.05 was considered as statistically significant. Results: Of the total 255 women, 85were confirmed adenomyosisby histological examination. Of the 85 cases, 39% (33/85) had a history of abortion, while only 25 % (44/170)women had abortion among non-adenomyosis group. Overall, women who had abortion were1.8 timesmore likely to have adenomyosis (95% CI 1.04- 3.17, P value=0.03) compared to women who had no history of abortion. Women with surgical abortions were 2.5 times more likely to develop adenomyosis (95% CI- 1.03- 6.21, P value=0.03) compared towomen with no abortion history. Conclusions: This study found that women,who had abortions,aremore likely to have been diagnosed with adenomyosis compared to women without abortions.Further studies, however, need to be carried out in order toextend findings of this study. Keywords: Abortion; adenomyosis; risk factors
The Association Between ABO Blood Groups and Adenomyosis
(Nepal Health Research Council, 2025) Pun, Sunita; Ojha, Neebha; Koirala, Poonam
Background: Several studies have investigated the relationships between female reproductive diseases and ABO blood groups. However, evidence regarding the potential association between ABO blood groups and adenomyosis remains limited. The aim of the study, thus, was to investigate the association between ABO blood groups and the risk of developing adenomyosis in Nepalese women. Methods: A cross-sectional study was conducted at the department of obstetrics and gynecology, Tribhuvan University Teaching Hospital, Maharajgunj, from 2016 to 2017. Statistical analysis was done using Statistical Package for Social Sciences (SPSS, 29). Odd ratio with their corresponding 95% confidence intervals, and P-value were calculated and analyzed. A P-value equal or < 0.05 was considered statistically significant. Results: A total of 249 with recorded ABO groups were included in this study. Of these, 85 cases (34%) were histologically confirmed to have adenomyosis. The most frequent ABO blood group was B (43%), while the least frequent group was AB (6%). Women with blood group B had a significantly increased risk of developing adenomyosis, with an odds ratio of 2.3 (95% CI: 1.22-4.43, P value = 0.01). Conversely, blood group A was associated with a significantly reduced risk of adenomyosis, with an odds ratio of 0.41 (95% CI: 0.19-0.89, P value= 0.03). Conclusions: This study demonstrated that women with blood group B have a 2.3-fold higher risk of developing adenomyosis, whereas those with blood group A may have a protective effect. Multicenter studies with larger sample sizes and diverse demographics groups are needed to substantiate these findings. Key Words: Adenomyosis; ABO blood group; risk factors.

Browsing by Author "Pun, Sunita"

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