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Browsing by Author "Rai, Snigdha"

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    Detection of Cervical Precancer Using Visual Inspection Method with Acetic Acid
    (Nepal Health Research Council, 2024) Baral, Gehanath; Oli, Lila; Verma, Sheela; Rai, Snigdha; Aryal, Parshuram; Tiwari, Suman
    Background: Cervical cancer screening is the priority activity of the government. Visual inspection with Acetic acid (VIA), Pap smear Liquid-based cytology, and HPV DNA testing are different methods of screening. VIA-based screening is the cost-effective method of screening in a resource-constrained setting like in our country as this doesn’t require cyto-histological testing, can be performed by trained paramedics too, and is as accurate as a cytological test. The aim is to explore pre-cancer cervical lesions by screening women in the community by visual inspection using acetic-acid. Methods: Community-based cross-sectional study done at a health camp setting for three months from March to June 2023. The married non-pregnant women of 30-60 years were screened. Descriptive tests as well as sub-group analysis performed by Chi-Square tests. Results: From ten community health camps, 1255 cases were screened and screen positivity was 14.3%. Positive results were proportionately distributed to all parity by 13-19%. Half of the positive results (47.2%) were in the 34-40 age group. There were no significant differences in screen positivity by parity or vaginal discharge. Menopausal women had 7.7% screen positivity. Conclusions: The prevalence of VIA positivity in the community was found double the previous facility-based prevalence; and there was no significant difference by parity, menopausal status, and vaginal discharge. The positivity was more in 30-45 years of age. Keywords: Cervical pre-cancer; screening; VIA.
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    Immature Teratoma in Pregnancy: A Case Report
    (Nepal Medical Association, 2023) Vaidya, Sapana Amatya; Rai, Snigdha; Jha, Anushree
    Abstract Immature teratoma is one of the rare malignant germ cell tumours presented in pregnancy. Here, we present 26-year-old pregnant women who had an incidental finding of left adnexal mass in an anomaly scan at 19 weeks of pregnancy. Laparotomy with peritoneal fluid cytology, left salpingo-oophorectomy and omental biopsy at 20 weeks of pregnancy revealed immature teratoma stage 1A, grade 2 in the histopathology report. However, she followed up with the metastatic mass in the pouch of Douglas at 30 weeks of pregnancy in magnetic resonance imaging despite being counselled for possible chemotherapy and surveillance. A baby with a good Apgar score and grade 3 immature teratoma in the metastatic mass was revealed following the exploratory laparotomy and cesarean section at 36 weeks of pregnancy. Fertility-sparing surgery with chemotherapy during pregnancy for high-grade tumours may result in a good prognosis.
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    Knowledge and Attitude Towards Human Papilloma Virus and Human Papilloma Virus Vaccine
    (Nepal Health Research Council, 2024) Poudel, Sandesh; Rai, Snigdha; Adhikari, Shree Prasad; Dhakal, Sheela; Rai, Nisha; Upadhyaya, Preetam Chandra; Shah, Pushkal
    Background: Human papilloma virus is the leading cause of cervical cancer with Human papilloma virus 16 and 18 being the commonest variants. The primary prevention by vaccination against HPV is finally gaining its momentum. This study aimed to evaluate the knowledge and attitude towards Human papilloma virus and Human papilloma virus vaccine and highlighted on the setback of their inadequate knowledge. Methods: This was a community based cross sectional study done among 120 women who attended cervical cancer screening camp at satellite clinic of Paropakar Maternity and Women`s Hospital at Bhaisepati of Kathmandu district. The interview was done one on one with a preformed questionnaire. Data was primarily entered in an individual form and analysis was done using SPSS version 23 program and was depicted in tables, diagrams and chart. Results: The mean age of the women was 41.8±9.9 with majority belonging to age group 41-50 years (47.16%), 88 (74%) women were multiparous,59 (49%) were uneducated and 50 (33%) were previously screened for cervical cancer. Among 27 (22%) of the women who had heard about HPV and knew that it causes cervical cancer, most of them have heard from social media while 110(91.6%) did not know about its vaccine and its availability while 100% of the participants had positive attitude towards receiving the information and keen on vaccinating their daughters. Conclusions: Knowledge and awareness of Human Papilloma Virus and its vaccine still remains low among the women in our society. However, there was high acceptance of HPV vaccine, indicating potentially high uptake rates in these communities. Keywords: Attitude; human papilloma virus; knowledge; vaccine.

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