Browsing by Author "Raut, Binod"
Now showing 1 - 2 of 2
Results Per Page
Sort Options
Publication Association between Medical Adherence and Perception of Disease among Hypertensive Patients visiting a Tertiary Care Teaching Hospital(Institute of Medicine, Tribhuvan University, 2024) Raut, Binod; Poudel, Nimesh; Thapa, DevikaAbstract: Introduction Medication adherence level is influenced by disease type and its severity, patient characteristics, socioeconomic factors, type of treatment and its regimen. Proper adherence to treatment is very important to obtain a higher therapeutic benefit. The aim of this study was to study the association between medical adherence and perception of disease among hypertensive patients. Methods It is a cross-sectional study involving 148 hypertensive patients based on convenience sampling technique conducted in the tertiary care Teaching hospital. Patients who have been taking antihypertensive medications for at least 6 months were enrolled. A structured questionnaire was used for data collection. JASP statistical software was used for data analysis. Results In this study 148 hypertensive patients taking medications were enrolled. Out of them, 54 (36.5%), 58 (39.2%) and 36 (24.3%) had low, medium and high level of adherence; while 94 (63.51%) 31 (20.95%) and 23 (15.54%) had perceived their disease as low, medium and high threat. Conclusion Medication adherence was found to be lower among the hypertensive patient, yet more than half had good perception. Regular monitoring and awareness program could be effective for the prevention of complications.Publication Comparative Study on Effectiveness and Safety of Atorvastatin with Rosuvastatin in Hyperlipidemic Patients at a Tertiary Care Hospital in Nepal(Institute of Medicine, 2020) Raut, Binod; Paudel, Nimesh; Shrestha, Deepti; Bhosekar, AnantABSTRACT Introduction: Hyperlipidemia is one of the most contributing factors to coronary heart diseases. Statins have become standard medicine in clinical practice to reduce total cholesterol, low density lipoprotein and to increase high density lipoprotein cholesterol. This study is conducted to compare the effectiveness and safety of atorvastatin with rosuvastatin in hyperlipidemic patients. Methods: This is a prospective observational study involving 150 patients conducted in the Department of Internal Medicine of Kathmandu Medical College and Teaching Hospital from July 2019 to March 2020. Patients newly diagnosed with hyperlipidemia were enrolled. Patients that were prescribed with 10 mg of atorvastatin and 5 mg of rosuvastatin by the treating physician once daily for 6 weeks were divided into two groups. Data was recorded in the customized proforma and the SPSS package version 20 was used for analysis. Results: Patients that were prescribed with atorvastatin were put in group I and those prescribed with rosuvastatin were included in group II with 75 participants in each group. The mean age of the patients were 50.56± 10.08 years in group I and 52.45±10.20 years in group II with male to female ratio of 3:1. The mean BMI of group I was 25.36±1.74 and that of group II was 26.48±2.21 before therapy. There was a significant main effect of duration (F1,74=401.02, p<0.001) on the TG and TC levels (F1,74=1134.23, p<0.001) as well as (F1,74=614.99, p<0.001) on the LDL and HDL levels (F1,74=146.38, p<0.001). Conclusion: Rosuvastatin was significantly more effective than atorvastatin in reducing levels of TG, TC and LDL-C. Rosuvastatin also significantly increased the level of HDL. Keywords: Atorvastatin, hyperlipidemia, rosuvastatin