NepMed Repository :: Browsing by Author "Regmi, D"

Browsing by Author "Regmi, D"

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Chest CT Scan Findings in Symptomatic Patients Infected with COVID-19 in Norvic International Hospital, Nepal
(Kathmandu University, 2021) Shahi, RR; Sapkota, MR,; Budhathoki, L; Manandhar, S; Regmi, D
ABSTRACT Background Coronavirus disease (COVID-19) is the recent global health emergency making it crucial for rapid diagnosis and intervention. Computed tomography (CT) is important for screening, diagnosis and evaluating severity and disease progress. Objective To assess the CT changes in COVID patients and study its relationship with various factors. Method A retrospective study was conducted at Norvic International hospital from August 2020 to November 2020 among RT-PCR positive symptomatic COVID cases who had positive CT changes. CT imaging data were analyzed by radiology expertise. Statistical analysis was carried out with the help of SPSS 16. Result Out of 120 patients, 75% were males and mean age was 54.70±15.56 years. The mean CT severity score was 18.35±6.87. Pure ground glass opacities was seen in 74(61.7%), reticulations 89(74.2%) and crazy-paving pattern 28(23.3%). CT scans with bilateral 118(98.3%) and peripheral involvement 109(90.8%) in all five lobes. CT- severity score was positively correlated with oxygen and mechanical ventilation requirement (P-value < 0.05 and 0.011 respectively). Conclusion CT findings including pure ground glass opacities, reticulations, bilateral and peripheral involvement involving all five lobes were more frequent. Our data suggest that CT-severity score significantly correlates with oxygen and mechanical ventilation requirements. KEY WORDS Coronavirus disease (COVID-19), Computed tomography, Ground glass opacity, Severity score
Comprehensive abortion care service at Kathmandu Medical College – An experience
(Kathmandu University, 2005) Pande, S; Sharma, M; Saha, R; Thapa, M; Shrestha, N; Regmi, D
Introduction: His Majesty’s Government amended the Nepal Criminal Code (Muluki Ain) – for Liberalising abortion law in the month of Chaitra 2058 (March 2002) and Royal Assent was given on 10th Asoj 2059 (27 th September 2002). Accordingly Comprehensive Abortion Care (CAC) Services was initiated in the country. Kathmandu Medical College after enlisting with Ministry of Health started this service from June 2004. Objective: This study was carried out to know- 1. Reasons for undergoing CAC service. 2. The complications after the CAC services. 3. The various contraceptive methods adopted by the client following CAC Methodology: Hospital based prospective study was carried out in Department of Obstetrics & Gynaecology at KMCTH from the period July 2004 to April 2005. Total 160 patients who asked for CAC were enrolled in the study. Counselling, history taking and general examination and per vaginal examination was carried out at the visit. CAC was performed with premedication with Doxycycline 100 mg and Ibuprofen 400 mg half an hour before the procedure. Paracervical block was also given with 1% xylocaine. MVA was performed as described in standard techniques. Patient was discharged after 1 – 2 hours of observation and with contraception opted by the clients. Results: • Main reason for performing CAC was unwanted pregnancy in 66.75%. • Complication following CAC was 1.25%. • Post CAC contraception was adopted by 93%. Most preferred method was Inj. Depoprovera Conclusion: The reason for CAC service asked by the patients was unwanted pregnancy. CAC service performed had minimal complication and also gave the opportunity for contraception. Key words: Comprehensive Abortion Care, Contraception, Safe Abortion.
Correlation between Sonoelastographic, Doppler and Histopathological Findings in Chronic Kidney Disease Patients in Tertiary Care Centre
(Kathmandu University, 2022) Jha, SK; Lohani, B; Pant, AD; Chataut, D; Regmi, D; Bhatta, U; Gautam, N; Jha, G
ABSTRACT Background Ultrasound (USG) with Doppler examination of intrarenal vessels is the imaging modality of choice employed in patients with renal failure and is commonly performed early in the clinical course. The pulsatility index (PI) and the resistive index (RI) of downstream renal artery have been found to correlate with renal vascular resistance, filtration fraction and effective renal plasma flow in chronic renal failure. Pathological process in any tissues alters their elastic properties which can be assessed non-invasively through newer technique like elastography. Objective To correlate the findings obtained by sonoelastographic, doppler and histopathological studies in chronic kidney disease patients. Method Study was done in 146 patients referred to Department of Radiodiagnosis and Imaging, TUTH for native renal biopsy. Renal sonographic morphology (length, echogenicity, cortical thickness), Sonoelastography (Young’s modulus) and Doppler parameters (peak systolic velocity, resistive index) were assessed. The grading of estimated GFR (eGFR) was calculated based on chronic kidney disease (CKD) criteria. Result Among 146 patients, 63 (43.2%) were females and 83 (56.8%) were males. Maximum patients were in age group of 41-50 years (25.3%) followed by age group 51-60 years (24%). Mean age of patient was 42.06±14.70 for males and 39.57±12.54 females. Maximum mean Young’s modulus was seen in eGFR stage G1 with 46.57±19.51 kPa followed by in stage G3a with 36.46±10.01 kPa and observed to be statistically non-significant (p=0.172). However, statistical significance difference was noted between the resistive index and elastographic measurement of Young’s modulus (r=0.462, p=0.0001). Minimum mean cortical thickness was seen in eGFR stage G5 with 4.42±1.48 mm followed by stage G4 with 5.57±1.24 mm (p= 0.0001). Cortical thickness is decreasing as eGFR stage was increasing in our study (p=0.0001). Resistive index is increasing with decrease in renal size (r=-0.202, p=0.015). Conclusion Ultrasonography along with doppler study and elastography have limited role in diagnosing the pathology of chronic kidney disease, however, it has significant role in the disease progression. KEY WORDS Chronic kidney disease, Doppler, Elastography, Resistive index, Ultrasonography

Browsing by Author "Regmi, D"

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