Browsing by Author "Rijal, Hima"
Now showing 1 - 4 of 4
Results Per Page
Sort Options
Publication Association of Ovarian Reserves with Body Mass Index, Age and Vitamin D in Infertile Females(Institute of Medicine, 2023) Rijal, Hima; Koirala, PoonamABSTRACT Introduction: Body mass index (BMI) may modulate ovarian reserve (OR) markers, and age-related fertility decline is well-established. Vitamin D has polygenetic effects on infertility, with its higher levels suggesting a positive correlation with OR markers. This study investigates the association of OR markers (AMH and FSH) with BMI, age and vitamin D in infertile females. Methods: An analytical study was conducted at Tribhuvan University Teaching Hospital, Nepal. The association of OR markers with BMI, age and Vitamin D level were analysed in infertile females over a year. Results: The study includes 186 infertile females, aged between 18 to 45 years. The study found no significant correlation between the OR marker (AMH) and body mass index (p = 0.92) or between OR (FSH) and BMI (p = 0.50). However, there was a significant negative correlation between age and BMI (p = 0.02). There was also a significant negative correlation between age and OR (AMH) (p = 0.04), but not between age and OR (FSH) (p = 0.09). And no significant correlation between vitamin D and OR (AMH/FSH) in infertile women, suggesting that vitamin D levels do not impact OR markers. Conclusion: The study found no significant association between OR markers, BMI, age and vitamin D in infertile women. Keywords: Anti-Müllerian hormone; body mass index; follicular stimulating hormone; infertility; ovarian reserve; vitamin D.Publication Postoperative Surgical Site Infection among Patients with Caesarean Delivery in the Department of Obstetrics and Gynaecology in a Tertiary Care Centre: A Descriptive Cross-sectional Study(Nepal Medical Association, 2023) Koirala, Poonam; Koirala, Ishita; Bajracharya, Sunita; Rijal, Hima; Ghimire, Asmita; Chamlagain, AnitaAbstract Introduction: Surgical site infections are the commonest nosocomial infections following surgeries. They not only increase the morbidity and mortality following surgeries but also have a great impact both psychologically and financially. The aim of this study was to find out the prevalence of postoperative surgical site infection among patients with caesarean delivery in the Department of Obstetrics and Gynaecology in a tertiary care centre. Methods: This descriptive cross-sectional study was conducted in the Department of Obstetrics and Gynaecology of a tertiary care centre after taking ethical approval from the Institutional Review Committee (Reference number: 495(6-11)E2 077/078). Data from 1 July 2021 to 1 July 2022 were collected between 1 September 2022 to 30 November 2022 from the hospital records. All the pregnant women undergoing caesarean delivery during the study period were included. Convenience sampling method was used. Point estimate and 95% Confidence Interval were calculated. Results: Out of 1326 patients who underwent caesarean delivery, surgical site infection was seen in 38 (2.86%) (1.96-3.76, 95% Confidence Interval). Among 38 women, anaemia was seen in 11 (28.94%), diabetes mellitus in 6 (15.79%) and hypertension in 5 (13.16%). Conclusions: The prevalence of surgical site infection following caesarean delivery was found to be lower than other studies done in similar settings.Publication Proteinuria among Pregnant Women Admitted to the Department of Obstetrics and Gynaecology of a Tertiary Care Centre(Nepal Medical Association, 2024) Ghimire, Asmita; Koirala, Poonam; Rijal, Hima; Chamlagain, Anita; Pant, Padam RajAbstract Introduction: Proteinuria is usually related with preeclampsia during pregnancy, although it can also be caused by other conditions such as renal disease or isolated proteinuria. Proteinuria during pregnancy can result in adverse fetomaternal outcomes. The study aimed to find the prevalence of proteinuria among pregnant women admitted to the Department of Obstetrics and Gynaecology of a tertiary care centre. Methods: A descriptive cross-sectional study was carried out among pregnant women in the Department of Obstetrics and Gynaecology after obtaining ethical approval from the Institutional Review Committee. Data of 14 April 2022 to 13 April 2023 was collected from 9 June 2023 to 9 September 2023 from medical records. The study included pregnant women aged 18-45 years, who were past 28 weeks of gestation and had a 24-hour urine protein measurement. Pregnant women who had insufficient medical records were excluded from the study. A convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval. Results: Among 3,914 pregnant women, proteinuria was seen in 61 (1.56%) (1.17-1.95, 95% Confidence Interval). The mean proteinuria in the study group was 1.5±2.75 gm/24 hr. In pregnant women with proteinuria, maternal complications were seen in 51 (83.60%) and foetal complications in 34 (55.73%) cases. A total of 47 (77.05%) underwent emergency lower-section caesarean section. Conclusions: The prevalence of proteinuria among pregnant women was found to be similar as compared to studies done in similar settings.Publication Thyroid Disorders and Prolactin Hormone and Their Association with Obesity in Infertile Women in a Tertiary Hospital of Nepal(Institute of Medicine, 2020) Maskey, Suvana; Rijal, HimaABSTRACT Introduction: Thyroid dysfunction has profound effects on menstrual function and female fertility. Hypothyroidism is often associated with increased prolactin level which again worsens the problem. This study was done to evaluate the prevalence of thyroid disorders in infertile women attending infertility outpatient department (OPD) in Tribhuvan University Teaching Hospital (TUTH) and to determine the association of hypothyroidism and hyperprolactenemia with obesity which is not well studied in our population. Methods: A hospital-based cross-sectional study was conducted in infertility OPD of TUTH reviewing women’s records who underwent infertility workup and relevant history, clinical finding and results of investigations including thyroid function test (TFT) and serum prolactin (PRL) level were documented. Descriptive and inferential statistical analyses were used to identify the prevalence and associations of predictors and outcome variables. Results: Out of 213 participants, the majority of the participants were obese (90; 42.3%) with mean (±SD) body mass index (BMI) being 24.8 ± 4.5 kg/m2. The prevalence of thyroid disorder was 18.4% including hypothyroidism 13.6% and hyperthyroidism 4.8%. There was no significant association of BMI and hyperprolactinemia with thyroid disorder as well as of BMI with hyperprolactinemia however the thyroid stimulating hormone (TSH) had significant positive correlation with prolactin (r=0.23, p<0.001). Conclusion: Thyroid disorders and hyperprolactinemia are commonly observed in infertile women, so they should be routinely screened during initial evaluation of infertility. As majority of the study population were obese, despite no significant association of BMI with thyroid disorder and hyperprolactinemia, the effect of weight gain on infertility cannot be overlooked. Keywords: Hyperprolactenemia, infertility, obesity, thyroid disorders