Browsing by Author "Shah, Ram Chandra"
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Publication Neuroprotective potential of green tea polyphenols in agerelated dementia: a review(Madhesh Institute of Health Sciences (MIHS), 2025) Shah, Ram ChandraABSTRACT: The clinical manifestations of dementia are brought on by the deterioration of particular cognitive areas, par- ticularly those linked to memory dementia. Nowadays, dementia is a severe issue that requires quick care. The avoidance dementia may be affected by dietary variables. Polyphenols are the main active components of tea. Epicatechin-3-gallate, epicatechin, gallocatechins, and gallocatechins gallate are the main polypheno- lic components of green tea, which are referred to as catechins. The amyloid cascade hypothesis states that naturally existing Aβ monomers form insoluble fibrils through a nucleation-dependent process, which are then deposited as plaques in the brain. Focused on green tea and carried out a thorough review of observational studies that examined the connection between green tea consumption and dementia. The publications that were recovered were then examined to determine whether they included original studies assessing a connec- tion between drinking green tea and dementia, Alzheimer’s disease, mild cognitive impairment, or cognitive impairment. These results seem to support the hypothesis that consuming green tea may reduce the risk of dementia, Alzheimer’s disease, moderate cognitive impairment, or cognitive impairment. More results from well designed and carried out cohort studies are required to provide conclusive evidence. Recent research dem- onstrating the protective effects of tea polyphenols against dementia is reviewed in this article and summarized.