Browsing by Author "Shah, Y"
Now showing 1 - 2 of 2
Results Per Page
Sort Options
Publication Prognostic Value of Rapid Test for Diagnosis of Dengue in Nepalese Patients during 2010 Epidemic(Kathmandu University, 2012) Pun, R; Shah, Y; Gupta, GP; Sherchand, SP; Pandey, BDABSTRACT Background Dengue is an emerging vector borne disease in Nepal and rapid diagnostic test is important for early diagnosis of the disease. Objectives The aim of the study was to evaluate the diagnostic accuracy of commonly used rapid immunochromatographic test kit in Nepal during 2010 dengue epidemic and to assess disease burden of dengue. Methods A total of 131 acute and nonacute serum samples were collected during recent epidemic of dengue in 2010 from clinically suspected Nepalese patients of different hospitals. Rapid immunochromatographic test kit was used for early diagnosis and enzyme immunosorbent was chosen as a reference assay. Results The sensitivity and specificity of rapid test was 70% and 76.54% respectively whereas the prevalence of the disease was 38.17%. The odds ratio for males was 1.8 however; the association with the disease was statistically not significant. Conclusion The diagnostic accuracy of rapid immunochromatographic test for dengue diagnosis was low (k=0.46). So, it should be substituted by highly sensitive test device for prompt diagnosis and health personnel should consider appropriate timing of sample collection for better performance of rapid test. KEYWORDS Dengue, Epidemic, Rapid testPublication The Double Burden of COVID-19 and Dengue in Nepal: The challenges ahead(Kathmandu University, 2021) Pandey, K; Dumre, SP; Dhimal, M; Pun, SB; Shah, Y; Fernandez, S; Morita, K; Pandey, BDABSTRACT Coronavirus disease 2019 (COVID-19) pandemic has caused significant impact on the health care system. As a consequence, diagnosis and treatment of vector borne diseases including dengue has been equally affected. Nepal is no exception to this, where COVID-19 cases is exponentially increased and all resources are concentrated on its prevention, control and management. Dengue, one of the major vector-borne diseases in Nepal, is apparently overlooked despite approaching the peak season of the disease. The aim of this paper is to describe the double burden of COVID-19 and dengue in Nepal, particularly highlighting the co-circulation and possible co- infections. This has posed higher risk of increased severity, more severe cases and deaths in Nepal. Moreover, potential misdiagnosis of these viral diseases may lead to delayed or, inappropriate treatment and poor allocation of resources. KEY WORDS Co-infection, COVID-19, Dengue, Nepal