Browsing by Author "Sharma, Rabindra"
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Publication Epidemiological Profile of Skin Diseases in a Tertiary Hospital of Kathmandu: An Annual Census(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2021) Paudel, Sushil; Sharma, Rabindra; Dahal, Sudip; Paudel, Indu AcharyaAbstract: Introduction: Skin diseases are eighth most common reasons for outpatient in Nepal, and fourth cause of disability globally. Skin diseases varies with the reason, season and socioeconomic status. As the socioeconomic conditions are changing, so are the disease patterns. We planned to report the current trend of skin diseases in Kathmandu and compare with similar studies in past. Materials and methods: Outpatient department records of Civil Service Hospital from the year 2075 Bikram Sambat were reviewed after ethical clearance from institution review committee and were analyzed after tabulation. Results: Total number of cases were 9886 (4.51% of total hospital attendance). In total 8097 cases were new, males were 4218 (52.1%) and females 3879 (47.9%). Most common diagnosis was eczemas (18.47%), followed by dermatophytosis (15.29%). Eczemas, chronic urticaria, psoriasis and lichen planus were more common in the adult population of more than 30 years. While infections and acne were more common in young adults, 15-30 years, in both the sexes. Tinea was common during summer and so was scabies in males, while in females, melasma peaked in summer and chronic urticaria during spring and winter. Conclusion: The pattern of skin diseases is changing with the time. Diseases of possible allergic and immunologic etiology are increasing and diseases with infective etiology are still a huge burden on society. Keywords: Nepal, Pattern, Skin diseasesPublication Patch Testing In Nepalese Population: A Single Center Study From Kathmandu, Nepal(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2019) Paudel, Sushil; Pun, Guma; Parajuli, Niraj; Sharma, RabindraAbstract: Introduction: Patch testing is a diagnostic tool used in investigation to identify specific allergens in allergic contact dermatitis (ACD). It helps find the prevalence and the trends of contact sensitization in the community. Objective: To report the two year patch test results from a central hospital in Kathmandu. Materials and Methods: Consecutive consenting patients of suspected ACD were patch tested with an Indian standard Series (Systopic) from June 2014 to August 2016. Results: Out of 141 patients tested, 89 were female (63.12%) and 52 were male (36.88%). Hand eczema was the commonest pattern (53 patients) followed by persistent and recurrent eczema (44 patients) and face eczema (25 patients). Fifty- five patients (39%) had at least 1 positive allergic reaction. Among these, 16.31% were male and 22.70% were female. The most common allergen was nickel sulfate (19.9%) followed by fragrance mix (7.8%) and paraphenyldiamine (PPD) (6.4%). Out of total positive cases 27 (21 females and 6 males) had shown strong positive reactions (++). The Nickel Sulfate was responsible in majority of cases (18/27 cases). Farmers had the highest (57.14%) rate of positive allergic reactions followed by housewives (39.62%). According to the regional eczema, patients with persistent and recurrent eczema of different parts of body had the highest rate of positive allergic reactions (47.72%). Almost half of patient with facial eczema (40%) had positive patch test. Conclusion: Larger studies are required in the different parts of the country to find a more accurate data regarding the sensitization pattern in Nepalese population. Keywords: Allergens, Dermatitis, Allergic Contact, Eczema, Nickel sulfatePublication Pattern of Pediatric Dermatoses in a Tertiary Referral Centre, Nepal(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2019) Sharma, RabindraAbstract: Introduction: Dermatological problems constitute at least one third of all outpatient visits to a pediatrician and similar number of all visits to a dermatologist involve children.Children are often exposed to climatic and social conditions that make them more likely to develop skin infections and skin injuries.Little is known about the impact of pediatric skin disease on health care systems in developing countries like Nepal. So, data on this study can be useful in monitoring changes in disease trends in children and planning health care programs. Objectives: To know the current status of disease trends and ethnic distribution of common dermatoses among children (hospital based) in this geographical locality. Materials and Methods: All children, 14 years and below, attending the dermatology out-patient department with any dermatoses were enrolled in the study. The diagnosis was made by dermatologists based on detailed history and appropriate investigations. Patients were divided into four different age groups. Results: A total of 424 children with skin related symptoms were enrolled in this study. The mean age of this population was 6.30 years and it ranged from 0.05(19 days) to14 years. A total of 146 infective and 278 non-infective dermatoses were encountered as the primary diagnosis. Infections and infestations were the most common group of disorders (34.4%, 146 cases), followed by dermatitis and eczemas (32.5%, 138 cases). Fungal infections were the most common infective conditions (11.6%, 49 cases). Conclusion: Infections and infestations were the most common etiologic group of disorders followed by dermatitis and eczemas. Fungal infections were the most common infective conditions followed by pyoderma. Keywords: Eczema, Ethnic Groups, Mycoses, Pyoderma, Nepal, Skin Diseases, InfectiousPublication Prevalence of Hepatitis C among Lichen Planus Patients(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2020) Sharma, Rabindra; Paudel, SushilAbstract: Introduction: The association between hepatitis C virus (HCV) infection and lichen planus (LP) has been studied widely. Extrahepatic manifestations including lichen planus are common among patients infected with HCV. The prevalence of HCV among lichen planus (LP) seems to vary geographically. Objective: This study was carried out to determine whether an association exists between LP and HCV infection. Materials and Methods: A total of 68 lichen planus (LP) patients identified clinically and histopathologically were screened for anti-HCV from blood samples. Results: Among the 68 patients of LP only 2 (2.94%) female patients had HCV infection. Conclusion: This study reveals very few patients of lichen planus being infected with HCV which is in line with a similar study done earlier in Kathmandu. Thus due to limited evidence to support an association between HCV and LP routine HCV screening is not recommended at this geographic location. Keywords: Hepatitis C, Lichen Planus, Nepal