Browsing by Author "Shrestha, Dhruba"
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Publication Bone Tuberculosis: Rare Condition Among Infants(Nepal Paediatric Society (JNPS), 2019) Bastola, Ramchandra; Adhikari, Neelam; Shrestha, Dhruba; Sigdel, Bhawana; Shrestha, Shree KrishnaAbstract: Bone tuberculosis in infancy has become rare these days. Here we report a case of 12 months old male infant who had presented with complaints of fever and skin rash for one month, along with protuberance of toe joint for 15 days. He was being treated with antibiotics, vitamin D and calcium without improvement. Further investigations led to mycobacterium positivity in bone biopsy. He was treated with anti-tubercular therapy and he responded to the treatment dramatically. So, though rare, it is important to consider bone tuberculosis when there are bony issues even in infancy, especially in endemic regions like ours.Publication Nepal Paediatric Society Clinical Guidance for Management of Sepsis and Septic Shock in the Paediatric Intensive Care Units in Nepal(Nepal Paediatric Society (JNPS), 2021) Basnet, Sangita; Shrestha, Dhruba; Amatya, Puja; Sharma, Arun; Bajracharya, Binod Lal; Shrestha, Anil; Shrestha, Sudeep; Rajchal, Pramila; Kafle, Raju; Shrestha, Devendra; Puri, Sangeeta; Bhatta, Anwesh; Pathak, Om Krishna; Shrestha, ShrijanaAbstract: Justification: Sepsis is a major cause of morbidity and mortality in Nepal. There is a lack of standardisation in the management of severe sepsis and septic shock. Additionally, international guidelines may not be completely applicable to resource limited countries like Nepal. Objective: Create a collaborative standardised protocol for management of severe sepsis and septic shock for Nepal based on evidence and local resources. Process / Methods: Paediatricians representing various paediatric intensive care units all over Nepal gathered to discuss clinical practice and delivery of care of sepsis and septic shock under the aegis of Nepal Paediatric Society. After three meetings and several iterations a standardised protocol and algorithm was developed by modifying the existing Surviving Sepsis Guidelines to suit local experience and resources. Recommendations: Paediatric sepsis and septic shock definitions and management in the early hours of presentation are outlined in text and flow diagram format to simplify and standardise delivery of care to children in the paediatric intensive care setting. These are guidelines and may need to be modified as necessary depending on the resources availability and lack thereof. It is recommended to analyse data moving forward and revise every few years in the advent of additional data.Publication Nepal Paediatric Society Guideline for use of Antibiotics in Critically ill Children in the Pediatric Intensive Care Unit(Nepal Paediatric Society (JNPS), 2021) Shrestha, Dhruba; Amatya, Puja; Sharma, Arun; Shrestha, Shrijana; Sharma, Yograj; Pathak, Santosh; Pokharel, Prakash Jyoti; Shrestha, Nipun; Pokhrel, Santosh; Dongol, Srijana; Raya, Ganendra Bhakta; Ghimire, Amrit; Koirala, Janak; Basnet, SangitaAbstract: Justification: Overuse and administration of unnecessary and inappropriate antibiotics are the leading causes for the increased antimicrobial resistance worldwide. Judicious use of antimicrobials can prevent this phenomenon. Objective: Create a collaborative outline for the use of antibiotics in the paediatric intensive care unit for various infections, based on evidence, taking into consideration local antimicrobial susceptibility patterns. Process / Methods: Under the aegis of Nepal Paediatric Society, this guideline has been developed after several meetings of paediatricians working in various hospitals in different parts of Nepal, looking into the prevalent diseases and local sensitivity patterns of antibiotics. Recommendations: This guideline will help standardize the treatment protocol in paediatric intensive care units in Nepal and help paediatricians decide the appropriate use of antibiotics promptly while managing critically ill children. Keywords: Antibiotics; antibiotic sensitivity; antimicrobial resistance; critically ill child; Paediatric Intensive Care UnitPublication Nepal Pediatric Society Guidelines for the Safe Transport of Critically Ill Children in Nepal(Nepal Paediatric Society (JNPS), 2021) Amatya, Puja; Shrestha, Dhruba; Joshi, Suchita; Sharma, Arun; Shrestha, Shrijana; Basnet, SangitaAbstract: Transport of critically ill children is associated with increased risk of morbidity and mortality in developing countries due to the lack of adequate resources and skilled personnel. Transport of the sick child remains a major challenge in Nepal as well. The main objective of this article is to describe the importance of safe transport, and be a resource and guide for health care personnel during inter-facility transport of sick children in Nepal. This guideline is based on consensus statement of Nepal Pediatric Critical Care Working Group (NPCCWG) under the aegis of the Nepal Pediatric Society (NEPAS). It includes different components of transport, namely essential equipment, patient preparation, communications, medications, and transport checklist, that are required during transport of sick children, taking into consideration the current resources available in our health care facilities.