Browsing by Author "Shrestha, E"
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Publication Adult Granulosa Cell Tumor of the Ovary Diagnosed after Laparoscopic Salpingoophorectomy(Kathmandu University, 2025) Ansari, SN; Shrestha, E; Kayastha, P; Bista, KBABSTRACT Ovarian malignancies of uncommon variety are seen in 10% of cases of all ovarian tumors. Approximately 5% of such cases are granulosa cell tumor of ovary (GCT). In adolecents, the adult type Granulosa cell tumor (AGCT) is rare and the major concern is fertility preservation. Prognosis of the adult type granulosa cell tumor is favorable after surgery, as most cases present at early stages. We report a case of an 18-year girl who presented to our center with histopathological report of the adult type granulosa cell tumor. She underwent laparoscopic left salpingoophorectomy at another center for a 28.5 X 22.5 cm right adenexal mass. The patient denied completion surgery at our center and remained on follow-up. Patient is doing fine on follow-up to date. In young girls who present with complex adenexal mass, a strong suspicion of rare ovarian malignancies like granulosa cell tumor should be considered. For cases with incomplete surgery but fertility concern granulosa cell tumor should be monitored vigilantly for recurrence. KEY WORDS Adenexal mass, Adolescence, Fertility preservation, Granulosa cell tumorPublication Clinical Profile and Management of Paederus Dermatitis: Insights from Teledermatology in a Tertiary Care Setting in Nepal(Kathmandu University, 2025) Shrestha, E; Basukala, MS; Mishra, A; Basnet, A; Karn, D; Tamang, AABSTRACT Background Paederus dermatitis is a cutaneous reaction caused by the contact of rove beetles (Paederus species) on the skin. Common in tropical regions, including Nepal, this dermatitis poses a diagnostic challenge in remote areas where dermatological care is limited. Teledermatology, employing telecommunications for remote consultations, has shown promise in addressing these limitations, yet its effectiveness in diagnosing and managing Paederus dermatitis in Nepal has yet to be thoroughly explored. Objective To analyze the clinical profile and management outcomes of Paederus dermatitis through teledermatology at a tertiary care hospital in Nepal. Method A retrospective cross-sectional study was conducted on 54 patients diagnosed with Paederus dermatitis through teledermatology at Dhulikhel Hospital between June 2024 and August 2024. Statistical analysis was performed to evaluate associations with demographic and clinical factors. Result The study comprised 54 patients (59.26% males and 40.74% females) with a mean age of 28.4 ± 6.6 years. The most frequent symptoms included itching with a burning sensation (35.2%) and pain (24.1%). Linear erythematous plaques were observed in 42.6% of cases. Only 20.4% reported direct insect contact. Correlation analysis showed weak relationships between age, symptom duration, and lesion count. Multivariate regression indicated a baseline symptom duration of 2.7 days, with no significant association between age or lesion count and symptom duration. Conclusion Teledermatology is a valuable tool in diagnosing and managing Paederus dermatitis in rural Nepal, where direct access to dermatological care is limited. Future research should focus on expanding teledermatology’s role in other dermatological conditions. KEY WORDS Dermatology, Paederus dermatitis, Pederin, Rural health, TeledermatologyPublication Prevalence and Severity of Gingival Enlargement Among Antihypertensive Drug Users: A cross-sectional study(Kathmandu University, 2024) Kafle, S; Shrestha, E; Dhital, BMABSTRACT Background Drug-induced gingival enlargement is a well-known consequence of the administration of some antihypertensive drugs, including angiotensin-converting enzyme inhibitors, beta-blockers, and calcium channel blockers. Objective To determine the prevalence and severity of antihypertensive drug-induced gingival enlargement and to assess the probable risk factors associated with gingival enlargement. Method A hospital-based cross-sectional study was conducted in patients attending the Outpatient Department of Periodontology and Oral Implantology, Chitwan Medical College and Teaching Hospital, Bharatpur, Chitwan, Nepal, from July 2023 to May 2024. A total of 246 patients of both genders taking antihypertensive medications for a variable period and meeting all inclusion criteria were selected for the presence of gingival enlargement and classified by severity. Descriptive analysis was performed in the Statistical Package for the Social Sciences (SPSS, v.23.0.) using the chi-square test. Result A total of 210 (85.36%) subjects taking antihypertensive drugs appeared to have gingival enlargement. Among them, 86 (40.95%), 69 (32.86%) and 55 (26.19%) were taking calcium channel blockers, β-blockers and angiotensin-converting enzyme inhibitors, respectively. Regarding its severity, a marked severity was observed in patients taking calcium channel blockers followed by angiotensin converting enzyme inhibitors and beta-blockers accounting for 51 (56.0%), 19 (29.7%) and 13 (14.3%), respectively. Conclusion Patients taking antihypertensive medications are at high risk for gingival enlargement, and inflammation is considered an important cofactor for the expression of this effect. KEY WORDS Antihypertensive drugs, Drug-induced gingival enlargement, Prevalence, Severity