Browsing by Author "Shrestha, Samir"
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Publication Anxiety and Depression among Reproductive Aged Women with Fertility Problem and Its Associated Factors: A Hospital-Based Cross-Sectional Comparative Study(Central Department of Public Health, 2024) Shrestha, Sushan Man; Shrestha, SamirAbstract Introduction: The infertility problem is one of the growing public health issues in Nepal and the anxiety and depression related to this problem is not much studied. Objective: The aim of this study is to find status of anxiety and depression among the reproductive aged women having fertility problem and its associated factors. Methods: A cross-sectional comparative study was conducted with a sample size of 177 respondents. Hospital Anxiety and Depression Scale was used to access the anxiety and depression of the respondents. Chi Squared test and multivariate logistic regression was applied to find the association of anxiety and depression with socio-demographic, personal and health related variables. Results: The status of no, mild, moderate and severe anxiety were 52.7%, 24.2%, 17.6% and 5.5% respectively in fertile group and 30.2%, 23.3%, 14.0% and 32.6% in infertile group. Similarly, the status of no, mild, moderate and severe depression were 64.8%, 29.7%, 4.4% and 1.1% in fertile group and 50.0%, 14.0%, 8.1% and 27.9% in infertile group respectively. Both anxiety and depression were found to be statistically significant between fertile and infertile groups. Occupation [AOR 0.407 (0.203-0.817)], perceived income stress [2.124 (1.062-4.249)] and fertility status [2.463(1.254-4.838)] for anxiety and difficulties in relationship between couple [8.216(2.365-28.548)] for depression was found to be statistically significant. Conclusions: This study revealed fertility status, occupation status, and perceived income stress as the factors associated to anxiety and difficulties in relationship between couple as the factor associated with depression. Keywords: Keywords: Infertility, anxiety, depressionPublication Comparison of Efficacy of Localized Narrow-Band UVB Therapy Versus Localized PUVA Therapy in Chronic Hand Eczema(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2023) Khadka, Dhan Keshar; Agrawal, Sudha; Rijal, Arpana; Shrestha, SamirAbstract: Introduction: Hand eczema is a type of dermatitis largely confined to the hands. Narrowband UVB (NBUVB) appears to be as effective as topical PUVA therapy in the treatment of chronic hand dermatitis. However, the risks of phototoxicity and dyspigmentation associated with local PUVA therapy make NBUVB therapy a preferable initial therapeutic option. Methods and Methodology: A total of 40 patients with chronic hand eczema were randomly divided into two groups: Group A (20) receiving localized NBUVB and Group B (20) receiving localized PUVA therapy. They were administered the designated treatment modality for the period of 8 weeks. They were evaluated every 2 weeks to see for the clinical response and any side effects. Results: In group A, there was around 47% and 85% improvement in Clinical Assessment Score (CAS) at weeks 4 and 8 respectively. Similarly, in group B, there was around 52% and 86% improvement in CAS at weeks 4 and 8 respectively. The improvement in terms of the mean of CAS in cases of group B was more compared to group A. (p=0.636 at week 4 and 0.578 at week 8). Conclusion: Light-based modalities of treatment in the form of localized NBUVB and PUVA can be considered as an alternative treatment of choice in cases of hand eczema as they have been shown effective by the reduction in the clinical assessment score. However, there was no statistically significant difference in the reduction in the mean clinical assessment score among the patients treated with either localized NBUVB or PUVA.Publication Postherpetic Psoriasis: A Rare Case Report Authors(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2025) Shrestha, Samir; Sah, Anil Kumar; Khadka, Varsha; Sitaula, Sabina; Gurung, KushalAbstract: Wolf’s isotopic response describes the phenomenon where a new, different skin disorder occurs at the site of a previously healed skin lesion. The most common primary and secondary diseases are herpes zoster and granuloma annulare, respectively. Psoriasis vulgaris is rare as a secondary disease, with only two cases reported. Here, we report another rare case of psoriasis vulgaris following a herpes zoster.