Browsing by Author "Singh, Rajesh Kumar"
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Publication Clinical Spectrum of Malaria in Hospitalised Children at a Tertiary care Centre in North India - A Retrospective study(Perinatal Society of Nepal (PESON), 2025) Pandey, Charu; Singh, Rajesh KumarAbstract: Introduction : Malaria continues to cause high morbidity and mortality in the tropical countries, children being among the vulnerable age group. We conducted a retrospective study at a tertiary care centre in northern India to determine the pattern of the disease in our area. Methods: A descriptive retrospective in children aged 1 month to 18 years of age, admitted at our paediatric unit, with positive antigen test and/or peripheral smear for malaria. Presenting features, clinical signs, laboratory parameters, treatment and outcome were recorded. Statistical analysis was done using freely available software online. Results: 57 patients tested positive for malaria. The parasite species found in all positive tests was Plasmodium vivax. 22 (38.5%) of patients were classified as severe malaria. M:F ratio of 1.03:1. Fever was the most common presenting complain (100%), followed by pallor (52.6%) and persistent vomiting (35%). Antimalarial given was injection Artesunate in 53 (93%) of patients, oral artemeter lumefantrine was started as primary treatment in 3 (5.26%) patients, while chloroquine was given to only 1 (1.7%) patient. Blood component transfusion was required in 11 patients. 54 (94.7%) patients improved and were discharged, while 1(1.7%) patient was referred to higher centre, 2 (3.5%) patients left against medical advice. Mean duration of hospital stay was 6.2 (±2.35) days. Conclusions: Plasmodium vivax was the leading cause of malaria at our institute, causing both severe and uncomplicated malaria. Plasmodium vivax is no longer a benign entity.