Browsing by Author "Tangbetani, Laila Lama"
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Publication Clinicoepidemiological Profile and Sexual Behaviour Pattern of Patients with Anogenital Warts(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2023) Pandit, Anup; Tangbetani, Laila Lama; Dangol, Nhuchhe Man Singh; Ranjit, SudinaAbstract: Introduction: Anogenital wart (AGW) is the infection of the anal and genital mucosa and their adjoining areas by Human papilloma virus (HPV) 6, 11. Genital HPV infections are transmitted primarily through sexual contact. This study determines the clinicoepidemiological profile and sexual behavior patterns in patients with AGW. Materials and Methods: A hospital-based descriptive cross-sectional study was conducted in patients diagnosed with AGW attending the Department of Dermatology and Venereology, Bir Hospital between November 2019 and December 2020. Results: A total of 77 patients including 58 males and 19 females diagnosed with AGW were studied. The warts were recorded more commonly in married individuals (62.3%). The most common sites of warts were penis (84.5% of males) and vulva (57.9% of females) followed by perianal skin, and perineum in both males and females. Of the various morphologies, dome shaped warts were most commonly observed (58.6% in males and 73.7% in females). The individuals with extramarital contacts were at significantly more risk of AGW than those without such contacts (P =0.001). AGW cases were seen more frequent in patients with syphilis and HIV (7.8% and 2.6% respectively) compared to general population. Conclusion: Genital warts were more common in 16 – 25 years of age, mostly married, and polygamous. Like all STD (sexually transmitted diseases), Genital warts (GWs) have important effects on the health of society and quality of life. Hence, awareness of the clinical presentations, sexual aspects, and possible risk factors of GWs leads to the use of effective protection measures.Publication Profile of Neurosyphilis Patients Admitted to a Tertiary Care Centre of Nepal: An Observational Study(Nepal Medical Association, 2025) Giri, Uma; Tangbetani, Laila Lama; karki, Anupama; Ghimire, Jagat JeevanAbstract Introduction: Neurosyphilis is a rare complication of untreated syphilis with limited literature.We aimed to look for demographic characters and clinical presentation of patients admitted with the diagnosis of neurosyphilis. Methods: This was an observational cross-sectional study that included analysis of records of neurosyphilis patients admitted to the National Academy of Health Sciences, Kathmandu, Nepal, from May 2015 to April 2024. All patients diagnosed with neurosyphilis were included, while those with incomplete data were excluded. The Centers for Disease Control and Prevention criteria were used to define and categorize neurosyphilis. Continuous variables were summarized as mean ± standard deviation for normally distributed data or as median and interquartile range for skewed data. Categorical variables were described using numbers and percentages. Results: A total of 53 cases were included in the study, with 31 (58.49%) males. The median age was 46 years (interquartile range: 37–60 years). Decreased vision was ovserved in 30 (56.60%) patients, and redness of the eye in 11 (20.75%) and headache in 4 (7.55%). Eye signs were observed in 43 (81.13%) patients. Cerebrospinal fluid Venereal Disease Research Laboratory (VDRL) test was positive in 11 (20.75%) cases. Based on Centers for Disease Control and Prevention criteria, 11 (20.75%) patients had verified neurosyphilis, 34 (64.15%) had likely neurosyphilis, and 8 (15.09%) had possible neurosyphilis. Iintramuscular benzathine penicillin was administered in 26 (49.06%) patients. Conclusions: There were more male patient with Neurosyphilis in our population. Decreased vision was the most common presentation. Likely neurosyphilis was most common diagnosis among studied population.