Browsing by Author "V, Gupta"
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Publication Bile leak detection by radionuclide scintigraphy(Kathmandu University, 2006) V, GuptaIntroduction: Bile leak after liver injury has been reported to be a complication associated with significant mortality. Tc99m-IDA (Tc: Technetium) nuclear scan allows rapid and noninvasive diagnosis of bile leak. Objective: An accidental case was referred for the detection of suspicious bile leak. Methods: The ultrasound could not detect any abnormality. Dynamic Hepatobiliary Scintigraphy (DHBS) using radiolabeled tracer was performed. Results: DHBS promptly detected the site of leak. Conclusion: This technique should be opted because it has been found to be quite sensitive, specific and accurate for detecting the bile leak. Whereas, Ultrasound and CT imaging are less sensitive and nonspecific. Though, they are initially helpful in determining the presence of abdominal fluid collections, they are unable to differentiate between a seroma, lymphocele, hematoma or bile leak. Hepatobiliary scintigraphy is more accurate because it can demonstrate continuity of these fluid collections with the biliary tree. Further, hepatobiliary scintigraphy can provide real-time assessment of hepatocytes function and bile progression from the liver to the intestine. Key words: Tc99m-IDA scan, Hepatobiliary iminodiacetic acid [HIDA] scan, DHBS, Cholescintigraphy, Hepatobiliary trauma, scintigraphyPublication Bone scintigraphy in the evaluation of cancer(Kathmandu University, 2005) V, GuptaBone scintigraphy being a highly sensitive modality is useful in the detection of skeletal metastases in cancer patients. The procedure does not pose any radiation risks to the patients. To improve the specificity of the modality, proper patient selection is important. This article explores the application of bone scintigraphy in detection of metastatic cancer with an insight about patient selection. Keywords: Bone Scan, Metastases, Tc99m-MDP, MalignancyPublication Physiopathologic atlas of thyroid scintigraphy(Kathmandu University, 2007) V, GuptaNuclear medicine is an excellent example of functional imaging. It has an established role in the evaluation and management of thyroid disorders. The physiologic and pathologic basis of radiotracer based thyroid imaging has been presented in this article. The same principles apply to the treatment of thyroid disorders using radioactive iodine. Keywords: Thyroid scan, radioiodine, I-131 ablation therapy.