Journal Issue:
Volume 16, No 1, Issue 61 JAN.-MARCH, 2018

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Volume

Number

Issue Date

2018

Journal Title

Journal ISSN

1812-2027

Journal Volume

Journal Volume
Volume: 16

Articles

Publication
Oral Systemic Connection
(Kathmandu University, 2018) Humagain, Manoj
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Publication
Growth and Development of Vascular Surgery in Community Based Hospital of Nepal
(Kathmandu University, 2018) Thermann, Florian
NA
Publication
Diagnostic and Treatment Delays among the Tuberculosis Patients in the Urban Area of Western Nepal
(Kathmandu University, 2018) KC, A; KC, R; Sharma, I
ABSTRACT Background Diagnosis and treatment of tuberculosis is vital for health system to identify, treat patients as early as possible and to reduce frequency of new cases of a disease among the contacts of known cases. Objective To determine the diagnostic and treatment delay in the urban population of the western, Nepal and factors associated to it. Method An institutional based cross-sectional study was conducted in urban area of Western Nepal. Category I 142 TB patients aged over 15 years visiting DOTs centre during period of three months were included in study. Interview schedule was designed to elicit information on socio- demographic characteristics and history of symptoms. Diagnostic and treatment delay was calculated, chi square test was applied to find associations and non – parametric tests (Mann Whitney U test and Kruskal Wallis H test) for evaluating group differences. Result Out of 142 TB clients, mean age was 38.12 years. Majority (58%) were males. Around 44% belong to upper, 30% middle and 26% lower economic class. Study showed median diagnostic delay 34 days (Q3=68 Days, Q1=19 Days), treatment delay less than a day (Q3=1 Day, Q1=0 Day) and total delay 33.50 days (Q3=71 Days, Q1=19 Days). Smear positive patients had significantly higher risk of diagnostic delay compared to negative (OR=2.18. P=0.035). However, no significant associations found between socio-economic/demographic classes with delay. Median delays was more amongst married (Q3=86 Days, Median =72 days, Q1=24 Days compared to single/separated (Q3=74 Days, Median =57 days, Q1=15 Days) and other socio-demographic variables had no significant differences. Conclusion Delay in diagnosis and treatment in Urban region of Western, Nepal was shorter compared to other places in Nepal and neighboring countries. Shorter delay for smear negative pulmonary tuberculosis raises doubt that cases are not examined according to the national TB control programs manual. KEY WORDS Diagnostic delay, DOTS, Treatment delay, Tuberculosis
Publication
Ethnic Variations of Blood Groups in a Medical College of Eastern Nepal
(Kathmandu University, 2018) Niroula, DR; Jha, MK; Limbu, P; Pokhre, I; Yadav, SK; Mukhopadhyay, S
ABSTRACT Background Red blood cells contain antigens in its membrane which are inherited according to Mendelian law. ABO and Rhesus blood group systems are considered the most important blood group systems for clinical procedures, blood transfusion, organ transplantation, anthropological study and medico-legal purposes. Determination of ABO and Rhesus blood groups and its frequency distribution in a multiethnic country like Nepal is important for effective management of blood banks, safe blood transfusion services. The trend of blood groups and its ethnic distributions in the eastern part of Nepal is still unknown. Objective To find the distribution of blood groups among the subjects of different ethnic groups of eastern Nepal. Method A cross-sectional perspective study was carried out among the subjects visited in the laboratory of Nobel Medical College, Biratnagar, Nepal for a period of one year from August 1, 2015 to July 30, 2016. Result The 11,960 subjects were included in the present study, among which 5012 were males and 6948 were females. The study revealed that in ABO system, blood group distribution was 34.80% O, 28.66% A, 27.66% B and 6.89% AB. With regard to Rh blood group system, Rhesus +ve was 96.79% and Rhesus –ve was 3.21%. O blood group dominant ethnic groups were Brahmin, Bhujel, Biswakarma, Shah, Gurung, Marwari, Magar, Mahato, Mandal, Newar, Sanyasi, Tamang, Terai Brahmin and Yadav. Similarly, blood group A dominant ethnic groups were Chhetri, Dhimal, Limbu, Rai and Muslim. Howerver, blood group B was dominant in ethnic groups, namely Biswakarma, Rajput, Satar and Tharu. Conclusion The frequency distribution pattern of ABO blood group was observed as O > A> B > AB and in Rhesus system, Rhesus +ve > Rhesus –ve. Variation in blood groups distribution was observed in various ethnic groups. KEY WORDS ABO system, Blood group, Eastern Nepal, Ethnic group, Rhesus system
Publication
Anxiety on Primigravid Women Attending Antenatal Care: A Hospital Based Cross-sectional Study
(Kathmandu University, 2018) Shrestha, S; Pun, KD
ABSTRACT Background High levels of anxiety during pregnancy have adverse effects on mother and baby. Objective To assess anxiety on primigravid women attending Antenatal Care. Method Analytical cross-sectional study was carried out on the primigravid women attending Antenatal Care out-patient department of Dhulikhel Hospital. Perinatal Anxiety Screening Scale (PASS) was used to assess anxiety on 502 women. Data were collected through face-to-face interview using Systematic Random Sampling Technique from May 2017 to December 2017. Chi-square test was applied to test the association between selected variables. All p- values less than 0.05 were considered statistically significant. Result The mean (± Standard deviation [SD]) age of the participants was 23.17±3.9 years. More than half (57.6%) of the women were from the age group 20-25 years. Just above two-fifth (41.4%) of the participants were in the third trimester of pregnancy. Out of 502 pregnant women, nearly half (46.4%) of them were at high risk of anxiety. High risk of anxiety was significantly associated with age and type of family. However significant associations were not seen between high risk of anxiety during pregnancy and residence, educational status, occupation, husband’s occupation and gestational period of women. Conclusion The high risk of anxiety on primigravid women was quite up. Anxiety during pregnancy was more likely to fall on younger women (age <20 years) and joint families in comparison to those women from age twenty and above and nuclear families respectively. KEY WORDS Antenatal care, Anxiety, Primigravid women

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