Journal Issue: Vol 23 No 1 Issue 66
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Volume
23
Number
01
Issue Date
2025
Journal Title
Journal ISSN
1999-6217
Journal Volume
Vol 23
(23)
Articles
Confronting the Threat of Predatory Journals: Time for Nepalese Academia to be Aware
(Nepal Health Research Council, 2025) Hamal, Pawan Kumar; Dawadi, Pravakar; Yogi, Prajwala
NA
Ensuring Integrity in Orthopaedic Research: Addressing Unethical Practices and Promoting Ethical Standards
(Nepal Health Research Council, 2025) Vaishya, Raju; Bhadani, Janki Sharan; Vaish, Abhishek; Joshi, Pramod
This review discusses the prevalence of these unethical behaviours, their far-reaching consequences on patient care, and the Orthopaedic field’s credibility. It highlights the need for effective strategies to promote ethical standards, emphasizing the importance of awareness among researchers and clinicians. The article outlines specific unethical practices, including data manipulation, which distorts treatment efficacy, and plagiarism, which diminishes originality and wastes peer review resources. Additionally, it addresses biased reporting and conflicts of interest, which can compromise objectivity in research findings. The review advocates for collaborative efforts among institutions and journals to foster accountability and transparency, ultimately encouraging a culture of ethical conduct within the Orthopaedic community. By ensuring rigorous standards and practices, the future of Orthopaedic research can be aligned with patient safety and trust, propelling the field toward meaningful advancements in patient care and treatment outcomes.
Keywords: Conflict of interest; data fabrication; ethics; plagiarism; research; research Integrity.
Metered Dose Inhaler among Patients with Respiratory Disorders
(Nepal Health Research Council, 2025) Aryal, Kalpana Paudel; Rai, Nisha; Banstola, Ratna Shila
Abstract
Background: Metered dose inhaler is the most recommended and efficient therapy for management of respiratory disorders but incorrect inhaler use has critical to get significant impact of medication. The study aimed to assess the knowledge and practice on Metered dose inhaler among patients with respiratory disorders.
Methods: Cross-sectional study was conducted among 126 patients with respiratory conditions in 2021 in a teaching hospital. A structured questionnaire was used to assess knowledge on using Metered dose inhaler whereas checklist created by the WHO Guide to Good Prescribing was used to evaluate patient’s practice on inhalation technique. Results: The results showed that 74 (58.7%) of the patients were female and belonged to age group 66-80 years (mean/SD 63.35±11.803). Over half of the patients i.e., 66 (52%) had a satisfactory level of knowledge whereas, only 2 (1.6%) patients were aware on the waiting time between each puff of Metered dose inhaler. The results showed that only 3 (2.4%) patients had practiced correct technique on Metered dose inhaler.
Conclusion: Though the higher proportion of the patients had satisfactory level of knowledge on Metered dose inhaler use but critical gap was seen in essential steps for using Metered dose inhaler. Healthcare providers should consider appropriate measure to increase the knowledge and correct use of Metered dose inhaler. That ultimately improves the quality of respiratory health of patients with respiratory disorders.
Keywords: Knowledge; metered dose inhaler; patients; practice; respiratory disorders.
Serum Vitamin B12 Level in Children with Type 1 Diabetes
(Nepal Health Research Council, 2025) Pradhan, Santosh; Thapa, Subhana; Shrestha, Pradeep Krishna; Jha, Bharat
Abstract
Background: Type 1 Diabetes Mellitus is known to be associated with multiple co-morbidities. Vitamin B12 deficiency is a potential co- morbidity that might have been overlooked in these patients. The aim of this study is to evaluate the serum level of vitamin B 12 in a well-defined population of Type 1 diabetes.
Methods: The cross sectional study carried out on 40 patients with Type 1 Diabetes Mellitus visiting endocrinology unit in Kanti children’s Hospital, Kathmandu, Nepal. Thirty healthy non diabetics were also selected. Serum C-peptide, vitamin B12, creatinine, blood glucose level and glycosylated hemoglobin were assessed in both groups. SPSS ver. 22 was used to analyze the data.
Results:The mean serum vitamin B12 level of the diabetic group was 206.92±82.18 pmol/L. Among the population 40.0% i.e. 16 out of 40 were found to be deficient and 37.5 % i.e. 15 out of 40 were subclinically deficient. Whereas the mean serum vitamin B12 level of the non diabetic group was 340.71±136.02pmol/L. Out of 30 only 2(6.7%) were deficient, 8 (26.75%) were found to be subclinically deficient. Significant difference was noticed in the mean serum level of vitaminB12 between these two groups.
Conclusions: This study shows the presence of low serum vitamin B12 levels in Type 1 Diabetics. The routine screening for this condition along with confirmatory test and detail clinical examination could benefit the patients with Type 1 diabetes.
Keywords: Autoimmune disease; Type 1 Diabetes mellitus; Vitamin B12.