Journal Issue: Volume: 21, No. 1 (2023)
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Volume
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Issue Date
2023
Journal Title
Journal ISSN
ISSN 2091-0231 eISSN 2091-167X
Journal Volume
Articles
Aesthetic Dermatology, The Rising Trend
(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2023) Keyal, Uma; Thapa, Deeptara Pathak
Abstract:
Aesthetic Dermatology, also known as cosmetic dermatology provides treatment for skin, hair or body that emphasizes on improving an individual’s appearance. It is widely conducted to treat conditions such as moles, wrinkles, scars, excess fat, skin discoloration, skin laxity, and cellulite. Benefits such as minimally invasive or non-invasive and relatively less time-consumption with better outcomes has foster the patients to seek these treatments. With soaring demand for these treatments, numerous myths and misconceptions regarding the field of aesthetic dermatology have arisen which need to addressed. Also, this constantly evolving field with new devices and tools requires extra vigilance, continue medical education and a governing body to have check upon negligent professional activity, if occurs any
Monkeypox - A Review
(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2023) Hussain, Ijaz; Shaukat, Shehla; Butt, Ghazala
Abstract:
The recent past emergence of pandemics has made the world prepare for all the worst-case scenarios. First COVID-19 pandemic caught us unaware, and since then, diseases like Dengue and Monkeypox are making us take steps to avert the casualties caused by these infections. Monkeypox is a viral disease caused by orthopoxvirus. It spreads from close personal contact with the patient. The disease is severe among children, pregnant, and immunosuppressed patients. Recent outbreak among MSM group has added it to be amongst sexually transmitted infections. It is usually self-limiting, but severe disease-causing deaths have been reported by infection, particularly with central African types. Prevention is possible by vaccination with smallpox vaccines. Treatment is still evolving, with new drugs like Tecoviramet showing promising results.
Dermatological Publications from Nepalese Dermatologist Before and During the COVID-19 Pandemic Period: A Review
(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2023) Parajuli, Niraj; Chapagai, Badri; Paudel, Sushil
Abstract:
Introduction: The COVID-19 pandemic created a nation-wide lockdown with hospital services resorting only to the emergency sections. Dermatology out-patient was closed with majority of services being deferred for a later date or through online platform. Here, we try to find whether Nepalese dermatologists were contributing to sciences through research.
Methods: A Google Scholar search using certain key words to search for publications done by Nepalese dermatologist during the pandemic was done for year 2020-2021 described as pandemic period. Similar search was conducted for year 2018-2019 for the same time frame called as pre-pandemic. All the publications were analyzed using appropriate statistical methods.
Results: A total of 197 publications were retrieved for pandemic period as compared to only 106 published articles in the non-pandemic period. Among 197 publications, 81 (41.11%) were published in PubMed indexed journal as compared to only 40 (37.73%) publications out of 106 total publications during the earlier period. However, the increase in the number was not statistically significant.
Conclusion: An interest among Nepalese dermatologists for academic publications was noted during the pandemic period. This might be due to the proper use of time during the lockdown and closure of out-patient department.
Comparing the Clinical Efficacy of Topical Application of Virgin Coconut Oil and 1% Clotrimazole Cream as an Adjuvant to Systemic Antifungal in Chronic Dermatophytoses: A Randomized Controlled Trial
(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2023) Chawla, Aakriti; Rastogi, Madhur Kant; Gahalaut, Pratik; Dubey, Varsha; Mahajan, Vasvi; Deshmukh, Rahul
Abstract:
Introduction: Dermatophyte infections have become a common entity with a prevalence ranging from 36.6-78.4%. Majority of the patients are from low socioeconomic background who favour topical treatment. High treatment costs of antifungal medication and consequent poor compliance have given rise to the need of an effective and economical topical preparation.
Objectives: To compare efficacy of topical 1% clotrimazole versus virgin coconut oil application as an adjuvant to systemic antifungals in dermatophytosis.
Materials and Methods: A total of 100 patients presenting to the dermatology outpatient department and diagnosed with tinea infection clinically and by potassium hydroxide mount were taken up for the study. The patients were randomized into two groups with 50 patients in each group. One group received virgin coconut oil while the other group received 1% clotrimazole cream twice daily application as the topical preparation. Mycological cure was assessed by potassium hydroxide mount and clinical improvement was assessed objectively by severity score for itch, changes in clinical signs and symptoms and subjectively by Dermatology Life Quality Index questionnaire. Statistical analysis was analyzed using SPSS software version 17.
Results: Virgin coconut oil and 1% Clotrimazole had equivocal response after 12 weeks of treatment with respect to potassium hydroxide mount positivity, itch severity, clinical improvement and changes in Dermatology Life Quality Index scores when used along with systemic antifungal.
Conclusion: Virgin coconut oil can be easily used as a topical emollient and antifungal preparation along with systemic antifungals in the treatment of dermatophytosis.
Low Dose Oxybutin in Primary Hyperhydrosis: A Prospective Study from a Tertiary Care Center in Nepal
(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2023) Aryal, Eliz; Shrestha, Prashanna Raj; Gautam, Sujan
Abstract:
Introduction: Hyperhydrosis is a clinical condition where there is excessive sweating beyond the physiological need of the patient’s body. This can directly or indirectly affect the quality of patients life. Oxybutin is widely used in urology as anticholinergic medication for bladder urge incontinence. It can be used safely at a high doses (over 15 mg/day) to treat urological disorder. It also acts against excessive sweating and can be used in cases of hyperhidrosis.
Objectives: To evaluate effectiveness of oxybutin at low dose and to assess the Hyperhidrosis Disease Severity Scale (HDSS) .
Materials and Methods: This is a hospital based cross-sectional study in primary hyperhydrosis. Oxybutin was prescribed to all patients of primary hyperhydrosis with gradual increment of dosage of 2.5 mg orally once a day to 5 mg twice a day. Patients were evaluated at zero wk (baseline), 4 wk, 8 wk, 12 wk and follow-up in 16 wks with Hyperhidrosis Disease Severity Scale (HDSS) along with adverse effects were noted.
Results: There was a significant difference in HDSS at zero wk (baseline) and 4th wk (p=0.001) at a dose of 2.5 mg once a day of oxybutynin. Also, a significant difference was noted (p=0.022) in HDSS between zero wk (baseline) and 12 wk. Similarly, a significant difference between HDSS at zero wk (baseline) versus the 16th wk was also noted.
Conclusion: Oxybutin is an anticholinergic drug with an emerging role in hyperhydrosis. Low doses have shown significant results with minimal side effects. The dose requirement varies among authors. Studies with long-term follow-ups with ideal protocol need to be established in the future.