Journal Issue: Volume: 20, No. 1 (2022)
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Volume
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Issue Date
2022
Journal Title
Journal ISSN
ISSN 2091-0231 eISSN 2091-167X
Journal Volume
Articles
Standardizing Editorial Process Towards Quality
(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Thapa, Deeptara Pathak; Pradhan, Sushmita
Abstract:
A quality journal depends upon well-organized, structured, and efficient editorial activity. In addition, it is also determined by robust peer-review, pellucid focus and scope of the journal, amiability to authors, and open access for scholarly exchange of scientific research for paramount researchers worldwide.
Leprosy Care in the Era of COVID - 19 Authors
(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Kahawita, Indira Padmapani
Abstract:
Leprosy care services are facing several challenges with the advent of the global COVID 19 pandemic.
The impact on case detection has been felt globally with the annual new cases declining by 37.1% from 2019 to 2020. This trend reflects the disruption in routine health care services and active case finding activities than a true drop in the incidence of leprosy. There are marked differences in the major determinants of the leprosy burden even within countries of south Asia. Disease modelling has indicated that well over 100% of new cases of leprosy have gone unreported during the pandemic.
Even though availability of MDT has not suffered significantly, other services like active case finding, post exposure prophylaxis and reconstructive surgery have been curtailed to a great extent. The use of new technology and social media to reach patients and deliver care have been encouraged.
Co infection has not shown any significant effect on either leprosy or COVID 19. Even patients who are on immunosuppressants for lepra reactions have not been shown to have a bad outcome in the face of coinfection. Continuation of MDT during active infection with COVID 19 has been recommended as both dapsone and clofazimine have shown anti-coronaviral activity.
Stigma and social discrimination have not been studied in detail. It is postulated that patients affected by leprosy may suffer more social discrimination as both leprosy and COIVD 19 have been associated with stigma.
Urgent action is needed to improve case detection in leprosy on a global scale as delay in diagnosis and treatment may lead to further nerve damage and disability.
Clinico-Histopathological Study of Cicatricial Alopecia in a Tertiary Care Center
(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Bista, Muna; Khadka, Dhan Keshar; Upadhyaya, Paricha
Abstract:
Introduction: Cicatricial alopecia (CA) comprises a group of disorders characterized by permanent destruction of the hair follicle and fibrosis on histopathologic examination. The similarities in the clinical presentation of various types of this disorder cause difficulty in prompt diagnosis, so histopathological assessment plays a pivotal role in the diagnosis.
Objectives: This study aimed to assess the clinical variants of cicatricial alopecia and compare the histopathology of the various subtypes.
Materials and Methods: In this cross-sectional study, 22 patients of cicatricial alopecia were enrolled and punch biopsies from the active site were taken for histopathological examination. Statistical analysis and correlation of clinical and histopathological features were done.
Results: Out of the 22 patients, 10 cases (45.45%) were confirmed as Lichen Planopilaris (LPP), seven (31.81%) as Discoid Lupus Erythematosus (DLE), two (9%) as Morphea, one (4.5%) each as Pseudopelade, Central Centrifugal Cicatricial Alopecia (CCCA) and Dissecting cellulitis (DC). There was a fair agreement between clinical and histopathological diagnoses (Kappa=0.384). The age ranged from 10 years to 60 years with the mean age of 32.32 ± 15.51 years.
Conclusion: There is high clinical and histopathological variability and similarities among the variants of CA, which represents a true diagnostic challenge. A precise and early diagnosis is possible if the clinico-histopathological correlation is employed.
Study of Correlation of Severity and Quality of Life in Patients with Congenital Ichthyosis
(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Hemrajani, Priyanka; Sharma, Mona; Dhali, Tapan; B.C, Sharath Kumar
Abstract:
Introduction: Congenital ichthyosis is a disorder of cornification of skin with various cutaneous symptoms. Quality of life is a subjective perception of patients regarding their disease status and treatment received. Dermatological disorders have poor quality of life associated with them as any other systemic disease.
Objective : The present study was conducted to assess the quality of life among patients of congenital ichthyosis, so that suitable remedial measures may be devised based on the same.
Materials and Methods: It was a hospital based cross-sectional study with total 120 patients enrolled for study duration of one year .Children’s Dermatology Quality Life Index (CDLQI) questionnaire was used to assess the quality of life among patients. Global disease severity scale and VAS scale for severity of ichthyosis was used along with recording of socio-demographic details.
Results: With a response rate of 87%, the sample size comprised of 104 subjects, aged between 0-15 years. Females outnumbered the sample by more than 2/3rd. ‘Symptoms and feelings’ was the most affected domain in the CDLQI. Itching, female gender and presence of scales were significant predictors of poor quality of life scores.
Conclusion: The present study shows the epidemiological correlation of patients with congenital ichthyosis and the predictors of poor quality of life score. Regular subjective assessment of quality of life among patients should be included in routine clinic visits, as counselling plays a very important role in these patients.
Comorbidities in Psoriasis, Cross-Sectional Study in Western Nepal
(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Basnet, Binamra; Kumar, Ajay; Khadka, Shreyasha
Abstract:
Introduction: Psoriasis is an immune mediated chronic inflammatory disorder with a worldwide prevalence of 0.5 to 11%. Prevalence of psoriasis in Nepal is around 3%. Psoriasis has many associated systemic diseases and conditions such as diabetes, hypertension, metabolic syndrome, hypothyroidism, of which the commonly associated condition is Metabolic syndrome. The objective of this study is to find the degree of association between psoriasis and other diseases such as hypothyroidism metabolic syndrome etc.
Materials and Methods: For this study, total number of fifty-two patients with equal number of age and sex matched controls were recruited with a total duration of study being six months. This is an observational cross sectional prospective study. For the qualitative data, Chi-square test was used and for quantitative data analysis Student’s t test was used.
Results: Out of the eight parameters [BMI, smoking, alcohol use, hypothyroidism, hypertension, fasting blood sugar(FBS),fasting triglyceride(TG), fasting high density lipoprotein] considering the p value of <0.05 to be significant, FBS & fasting TG were found to be significant. When the means of FBS and fasting TG were compared between the cases and controls, there was notable relationship between the difference of means and the standard errors of means (p value=0.01 for FBS and p value=0.017 for fasting TG) as calculated by Student’s t Test.
Conclusion: In this study, there was a statistical significance between the fasting blood sugar(FBS) levels of the cases and controls (p value=0.01) and also between the fasting triglyceride levels of cases and controls (p value=0.017).