Journal Issue: Volume: 1, No. 2 (2024)
Loading...
Volume
Number
Issue Date
2024
Journal Title
Journal ISSN
ISSN 3059-9156 (Print), ISSN 3059-9164 (Online)
Journal Volume
Articles
STROBE Guideline for Observational Studies
(Rapti Academy of Health Sciences (RAHS), 2024) Phuyal, Navindra
NA
Spectrum of HRCT Chest Findings in RT-PCR positive COVID-19 Patients at a Tertiary Care Center in Mid-Western Nepal: A Retrospective Cross-Sectional Study
(Rapti Academy of Health Sciences (RAHS), 2024) B. C., Bom; Khanal, Bipin; K. C., Achhita; Subedi, Raj Kumar; K. C., Anuprash
Abstract:
Introduction: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causes a pulmonary infection called as coronavirus disease (COVID-19). High-resolution computed tomography (HRCT) of the chest plays a crucial role in diagnosis, assessing the lung involvement with its severity in COVID-19. The objective of this study was to describe the pattern of HRCT chest findings in lab-proven, real- time RT-PCR-positive COVID-19 patients.
Methods: This was a descriptive cross-sectional study conducted at Rapti Academy of Health Sciences (RAHS), the then COVID-19 patient treatment site in Lumbini province, from February 2021 to October 2021 among 78 RT-PCR-positive COVID-19 patients based on HRCT chest findings. Data collection was done after receiving ethical approval from the Institutional Review Committee of RAHS. Data analysis was performed using Statistical Package for the Social Sciences version 27.
Results: Among 78 RT-PCR-positive COVID-19 patients, 51 were male and 27 were female, with a mean age of 51.28±14.35 years. HRCT chest showed ground glass opacities (GGO) in 74 (94.87%), followed by atelectatic band in 24 (30.77%), interlobular septal thickening in 22 (28.21%), consolidation in 20 (25.64%), GGO and consolidation in 17 (21.79%), crazy-paving pattern in 11 (14.1%), and other chest findings in 5 (6.41%) patients.
Conclusion: The most common HRCT chest findings of COVID-19 were ground-glass opacities, while atelectatic band, interlobular septal thickening, consolidation, and crazy-paving pattern were other important findings. Thus, HRCT chest imaging is crucial for both diagnosing and assessing the severity of COVID-19 patients.
Pattern of Injury and Computed Tomography Findings in Patients with Cranio-Cerebral Trauma
(Rapti Academy of Health Sciences (RAHS), 2024) Bagale, Deepak; Pangeni, Roshan; Baral, Santosh; Subedi, Nuwadatta
Abstract:
Introduction: Traumatic brain injury (TBI) is the leading cause of fatalities from trauma and the main cause of disability under the age of 40 years. The estimated incidence of TBI in Nepal slightly surpasses the global average of 369 per 100,000. This study aims to identify the types of head trauma and patterns of CT scan findings, which will be beneficial in managing the patients and modifying the treatment protocol accordingly.
Methods: The study was conducted in the department of Radiology of Western Regional Hospital, Pokhara Academy of Health Sciences, from March to August 2024. This was a descriptive cross-sectional study conducted with 220 patients of all age groups coming for a CT scan of the head due to trauma to assess the causes and pattern of injuries.
Results: The mean age of the patients was 37.29±21.75 years and males were twice in number compared to females. More than 50% of patients had head injuries from road traffic accidents and 48.18% had fall injuries. The CT scan findings demonstrated that scalp hematoma was seen in 61.36% and skull fracture in 29% of patients. Amongst intracranial findings, contusion was seen in 6.82% of patients, subdural haemorrhage in 5.91%, epidural haemorrhage in 3.64%, and subarachnoid haemorrhage in 2.73%.
Conclusion: Almost 74% of people with head injuries who underwent a CT scan had some type of abnormal findings, where extra-cranial hematoma was more common than intracranial hematoma. Preventive strategies should be developed to minimize head injuries, and effective treatment planning is essential.
Morphological and Immunophenotyping Profile of Acute Leukemia: A Study from a Tertiary Level Hospital in Nepal
(Rapti Academy of Health Sciences (RAHS), 2024) Bishowkarma, Sabita; Bishowkarma, Sabita; Shrestha, Anjan; Shrivastav, Shreya; Rasaily, Suresh
Abstract:
Introduction: Acute leukemia is a heterogeneous disorder necessitating a multidisciplinary diagnostic approach. Flow cytometry is essential for lineage assignment and maturation stage identification. This study aims to determine the frequency and immunophenotyping of acute leukemia at Tribhuvan University Teaching Hospital (TUTH).
Methods: Conducted from January 2020, to December 2021, this cross-sectional study analyzed 504 bone marrow aspiration samples. Among these, 97 (19.2%) cases were identified as acute leukemia. Patient demographics, morphology, and immunophenotyping features were recorded and analyzed.
Results: Of the acute leukemia cases, 66% were male and 34% female. The pediatric population comprised 62.9%, while adults made up 37.1%. Cytochemical staining was performed in 92 cases, revealing 67% as acute lymphoblastic leukemia (ALL) and 33% as acute myeloid leukemia (AML). Flow cytometry was conducted on 84 cases, leading to diagnoses of 30 AML, 45 B-ALL, and 9 T-ALL.
Conclusion: Acute leukemia can affect all age groups with male preponderance. ALL is more prevalent in children, while AML is more common in adults. Immunophenotyping is critical for the classification and subtyping of acute leukemia, enhancing diagnostic accuracy and guiding treatment strategies.
Burden of Gallstone Disease Among Patients Presenting to the Surgery Department in a Tertiary Care Center: A Descriptive Cross-Sectional Study
(Rapti Academy of Health Sciences (RAHS), 2024) Dwa, Manoranjan; Bajagain, Santosh; Patel, Om Prakash; Shrestha, Rahul; Shrestha, Dristi
Abstract:
Introduction: The frequency of gallstone disease varies worldwide. Female gender, a family history of gallstones, obesity, diabetes, metabolic syndrome, estrogen therapy, dietary habits, and an inactive lifestyle increase the risk. Symptomatic individuals experience abdominal pain and indigestion, occasionally leading to complications, while many remain asymptomatic.
Methods: A retrospective, descriptive, cross-sectional study was conducted at Nepal Armed Police Force Hospital. Data of patients visiting the surgery department over a period from December 01, 2023 to November 30, 2024 was taken from the record section of the hospital. The ethical clearance was obtained from the Institutional Review Committee (registration number: NAPFH-007/2024). Patients aged 18 years or above were included, and those having common bile duct calculus, with biliary malignancy, in an immunocompromised state, and pregnancy were excluded.
Results: Out of 1835 patients, gallstone disease was observed in 210 (11.44%). 149 of them (70.95%) were females. 128 (60.95%) cases had multiple gallstones while 82 (39.05%) cases had a solitary gallstone. 170 (80.95%) cases presented with abdominal pain, whereas 30 (14.29%) remained asymptomatic. 19 (9.05%) cases presented with acute cholecystitis. Laparoscopic cholecystectomy was the commonest modality of management (76.19%).
Conclusion: Prevalence of gallstone disease was 11.44%, similar to other literature. Further research on gallstone disease helps to understand the disease in these settings.