Journal Issue:
Volume: 42 No. 2 (2022)

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2022

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ISSN 1990-7974 eISSN 1990-7982

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Journal Volume
Volume: 42

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Publication
Prevalence of Cleft Lip and Palate in the Developing Countries of Asia and Africa: A Review Authors
(Nepal Paediatric Society (JNPS), 2022) Shrestha, Ashish; Hoang, Ha; Gardner, Sue; Pradhan, Archana; Crocombe, Leonard
Abstract: Introduction: The objective of this paper is to review the literature on the incidence of cleft lip and palate (CLP) in the developing countries of Asia and Africa. The existing literature tends to focus on developed countries and there is lack of research in developing countries. Methods: The studies that met the inclusion criteria were reviewed and data extracted. There were 20 studies done in Asian and African countries which were included. Results: The incidence of CLP in Asian countries is markedly greater than in African countries. Most studies report a male predominance in CLPs and a female predominance in cleft palates. The male dominance is seen more than other developing countries which is consistent with other Asian countries and the same has been found in African countries. In the Nepalese study, females were slightly more affected than males among all clefts. The incidence or prevalence in the frequency and types of malformations of CLP in developing countries has been provided. Conclusions: The review underlines the need for an aggressive approach to prevent and control CLP in patients in developing countries.
Publication
A Quality Improvement Initiative on sustaining Kangaroo Mother Care Practices During COVID Pandemic
(Nepal Paediatric Society (JNPS), 2022) Apoorva; Anjum, Sadiqua; L, Swapna; M, Alimelu; Singh, Himabindu; Kalyan
Abstract: Introduction: COVID-19 pandemic has affected the KMC practices in our SNCU. Lack of clear guidelines and training about continuing KMC in COVID-19 times has further lead to decrease in KMC practices. Methods: This is a prospective single centered quality improvement study conducted in the inborn unit of a tertiary care hospital. Intervention phase was done in August and September 2020. Preterm mother-infant dyads who were admitted in the inborn Level 2 Neonatal care unit with birth weight less than 2000 grams were enrolled in this study. A QI team comprising of resident doctors, nurses and supporting staff and a lactation counsellor was formed. The potential barriers for prolonged KMC were evaluated using fish bone analysis. A variety of measures were introduced and subsequently tested by seven plan-dostudy-act (PDSA) cycles. Data on percentage of initiation of KMC was measured by bedside nurses on daily basis and the data was plotted on run chart every week during implementation phase. Results: 116 eligible mother-infant dyads were studied during implementation period (50 days). We achieved our goal by step-wise implementation of changes through multiple PDSA cycles. The percentage of initiation of KMC among eligible preterm infants has increased from baseline of 43.4% to 83.3% and duration of KMC from 1.5 mean hours to 4.5 hours over a period of eight weeks. Conclusions: Ongoing quality improvement measures increased the percentage of initiation and duration of KMC among eligible preterm infants without addition of extra man power.
Publication
Association between Serum Magnesium to Calcium Ratio with Level of Asthma Control in Children
(Nepal Paediatric Society (JNPS), 2022) Kundu, Tapan Kumar; Dutta, Arpan; Chatterjee, Abhilash; Chowdhury, Aditi
Abstract: Introduction: Bronchial asthma is an inflammatory reversible obstructive airway disease. This study aims to determine the association between serum magnesium to calcium ratio with level of asthma control in children by comparing serum magnesium to calcium ratio between - children with well controlled, partly controlled and uncontrolled asthma. Methods: An analytical cross sectional study was done on 90 children diagnosed with bronchial asthma between five to 12 years age from January 2019 to June 2020. Children were selected from the outpatient and inpatient departments of paediatric medicine of a tertiary care medical college hospital. They were classified into well controlled, partly controlled and uncontrolled groups as per Global Initiative for Asthma (GINA) assessment of asthma control in children. The serum magnesium to serum calcium ratio of these children were compared between the groups classified. Results: Mean level of serum magnesium to calcium ratio in well controlled group was 0.29857 (SD 0.07633), partly controlled 0.2439 (SD 0.0532), uncontrolled 0.2545 (SD 0.04467), respectively. Serum magnesium to calcium ratio more than or equal to 0.3 was positively correlated with well controlled asthma. Comparisons of serum magnesium to calcium ratio of well controlled group with partly controlled, uncontrolled and both partly and uncontrolled were statistically significant. Conclusions: Higher serum magnesium to calcium ratio is associated with well controlled asthma. In our study, serum magnesium to calcium ratio more than 0.3 is significantly associated with well controlled asthma.
Publication
Childhood Asthma and its Associated Factors Among Children Attending a Tertiary Level Hospital Kathmandu
(Nepal Paediatric Society (JNPS), 2022) Lamichhane, Narayani; Upreti, Kamala; Shrestha, Saraswati; Pradhan, Mary; Bhandari, Bhagawati
Abstract: Introduction: Childhood asthma is one of the most common non-communicable chronic pulmonary diseases of children and causes considerable morbidity. Prevalence of childhood asthma has grown dramatically in developed as well as developing countries. The objective of the study was to find out the factors associated with childhood asthma among children attending Kanti Children’s Hospital, Kathmandu, Nepal. Methods: Descriptive, cross-sectional study design was adopted and 152 parents were selected by using non probability purposive sampling technique. Data was collected using pre tested structured with an interview schedule after permission from concerned authorities. The data was analyzed by using descriptive and inferential statistic with SPSS IBM 16. Results: The finding of the study revealed that various factors were associated with childhood asthma. Among child related factors, age of children 6 years and above (p-value = < 0.001, OR = 4.190, 95% CI: 1.814 - 9.678), absence of exclusive breast feeding (p-value = 0.021, OR = 2.14, 95% CI: 1.062 - 4.351), history of recurrent allergy and rhinitis (p-value 0.049, OR = 1.9117, 95% CI: .953 - 3.856) and influenza vaccine (p-value = 0.001, OR = 3.714 95% CI:1.691-8.157) and in maternal factors, history of asthma in mother (p-value = 0.002, OR = 13.662, 95% CI:1.729 - 107.994), and on environmental factors, presence of dampness at home (p-value = 0.001, OR = 3.7142, 95% CI: 1.5584 - 9.3408) were found to have significant association with childhood asthma. Conclusions: It could be concluded that 50.7% of children were diagnosed as asthma. Several factors were associated with childhood asthma. Children age 6 years and above, lack of exclusive breast feeding, history of recurrent allergy and rhinitis and presence of dampness at home, maternal history of asthma and seeking of influenza vaccine were found significant association with childhood asthma.
Publication
Clinical Patterns and Outcome of Low Birth Weight Babies Admitted in NICU Tertiary Hospital of Western Nepal
(Nepal Paediatric Society (JNPS), 2022) Shrestha, Bandana; Subedi, Nabraj; Thapa, Namrata KC; Bhattarai, Arjun
Abstract: Introduction: Low birth weight (LBW) is one of the major determinants of neonatal morbidity and mortality. The survival and outcomes of LBW infants varied from hospital to hospital within a country. The objective of the study is to identify the clinical patterns and hospital outcome of LBW babies in a Tertiary care centre, Pokhara. Methods: A descriptive cross-sectional study conducted in a tertiary hospital after taking ethical approval from the institutional review board. Data on all the LBW babies admitted in Neonatal Intensive Care Unit from 15th May 2019 to 16th October 2020 were retrospectively reviewed. Data entered in excel and descriptive analysis were done in SPSS version 25. Results: Of 198 LBW babies, 120 (60.6%) were males and 78 (39.4%) females. Mean birth weight was 1.67 kg (± 0.42 SD), median 1.7 kg, ranging from 0.6 kg to 2.4 kg. Mean gestational age was 32.86 weeks (± 2.72 SD) and median was 33 weeks. 187 (94.4%) were preterm and 11 (5.6%) term. By birth weight, 17 (8.6%) were found to be ELBW, 53 (26.8%) VLBW and 128 (64.6%) LBW. 143 (72.2%) were AGA, 54(27.2%) SGA and one was LGA. Hyperbilirubinemia, neonatal sepsis and hypoglycemia were common problems encountered in NICU. Inadequate ANC, premature rupture of membrane, and low hemoglobin were the common maternal factors for LBW babies. Conclusions: Prematurity was the major cause of LBW and majority were male babies. LBW babies had relatively more problems in NICU.

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