Browsing by Author "Amatya, Isha"
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Publication Alteration of Thyroid Hormone among Patients with Ischemic Stroke visiting a Tertiary Care Hospital: A Descriptive Cross-sectional Study(Nepal Medical Association, 2021) Bashyal, Saroja; Gorkhaly, Manen Prasad; Devkota, Rameshwor; Devkota, Ramila; Regmi, Pradeep Raj; Amatya, IshaAbstract: Introduction: Stroke is broadly classified as cerebral infarction, intracerebral hemorrhage and subarachnoid hemorrhage. Neuroendocrine profile is altered in acute ischemic stroke and there is a link between hypothyroidism and atherosclerosis which in turn may lead to stroke. The objective of this study was to find out the prevalence of alteration of thyroid hormones in patients with ischemic stroke in a tertiary care center. Methods: This descriptive cross-sectional study was conducted from June to December 2019 in a tertiary care center. Ethical approval was taken from Institutional review board of National Academy of Medical Sciences (reference number: IM 175). Patients with a diagnosis of stroke, without evidence of cardioembolic source, history of liver disease, renal failure and thyroid disease and who do not use thyroidal supplementation within 180 days prior the event were included. Convenience sampling was done. Data was entered in Microsoft Excel and analyzed using Statistical Package for the Social Sciences version 22. Point estimate at 90% Confidence Interval was calculated along with frequency and percentage for binary data. Results: The prevalence of altered thyroid levels among 73 patients was 13 (17.8%) (90% Confidence Interval= 10.44-25.16). Among them 11 (15.1%) were hypothyroid and 2 (2.7%) were hyperthyroid. Among severity of hypothyroid cases, subclinical hypothyroidism grade IA was seen in 51 (70%), subclinical hypothyroidism grade IB was seen in 22 (30%), Conclusions: The prevalence of altered thyroid levels among patients undergoing ischemic stroke was similar to the findings of other international studies.Publication Modern Paediatric Radiology: Meeting the Challenges in CT and MRI(Nepal Medical Association, 2022) Regmi, Pradeep Raj; Amatya, Isha; Paudel, Sharma; Kayastha, PrakashAbstract Radiology plays a very important part in the diagnosis, treatment, and follow-up of children. Computed tomography and magnetic resonance imaging are the two most crucial developments in the modern era. However, the two modalities have their challenges to overcome. Radiation dose is the most unwanted side effect of computed tomography scans while longer scan time along with sedation is a major disadvantage in children during magnetic resonance imaging. Paediatric-specific protocol selection and limiting the exposure to the area of interest aid in reducing the dose during computed tomography scans. Faster scan protocols and sequences can result in imaging without sedation in magnetic resonance imaging. Considering the radiation exposure, "as low as reasonably achievable" principle should be followed strictly in the paediatric population. In this article, possible ways for minimising the radiation dose in computed tomography, as well as effective, short, and sedation-free magnetic resonance imaging, are discussed.Publication Naso-Orbito-Ethmoid Fibrous Dysplasia, a Rare Case in a Rare Location for Radiologists: A Case Report(Institute of Medicine, 2022) Regmi, Pradeep R; Kayastha, Prakash; Amatya, IshaABSTRACT Fibrous dysplasia is a non-inherited but congenital disorder which is characterised by the replacement of normal bone by an excessively proliferative cellular fibrous connective tissue intermixed with irregular bony trabeculae. Fibrous dysplasia may be localised to the single bone (monostotic form) or multiple bones (polyostotic form). About 25-30% of the facial dysplasia is associated with cranial or facial involvement. Imaging plays an important role in diagnosis and follow-up in the cases of cranio-facial fibrous dysplasia because of the anatomical complexity of the region. We have described herein a rare case of fibrous dyplasia involving naso-orbito-ethmoid region in radiological perspective. Keywords: Computed tomography, fibrous dysplasia, naso-orbito-ethmoidPublication Papillary Carcinoma of Thyroid in a Child, Rare but Aggressive: A Case Report(Institute of Medicine, 2021) Regmi, Pradeep R; Amatya, Isha; Paudel, Sharma; Kayastha, PrakashABSTRACT Thyroid nodules are uncommon in childhood than adult population. Thyroid malignancies are more common in the detected nodules comprising 22-26% in paediatric age groups in comparison to 5-15% of the adult population. In addition, thyroid malignancies are more aggressive in children than in adults with nodal and pulmonary metastasis. Despite having more recurrent rate than in the adults, survival seems to be better. We are presenting a case of an 11-year-old child presented to our clinic with swelling of neck for 3 months duration. Diagnosis was made through ultrasound, computed tomography and histopathological analysis. Therefore, diagnosing a case with papillary carcinoma of thyroid in children is very challenging and demanding the expertise. Paediatric radiologist could play a vital role in diagnosis which leads to proper management. Keywords: Children, computed tomography, papillary carcinoma, ultrasoundPublication Pediatric Radiology in Era of COVID-19, International Consensus and What Lies Beyond Pneumonia: A Review(Nepal Medical Association, 2021) Regmi, Pradeep Raj; Amatya, Isha; Paudel, Sharma; Kayastha, PrakashAbstract: Diagnostic radiology plays a crucial role in children. The pediatric population has been less studied than the adult population since the initial period of the COVID-19 pandemic to date. Realizing the potential utility of structured reporting, different guidelines and international consensus statements regarding COVID-19 in the pediatric population have been released in recent times. Different clinical and radiological manifestations in children have been evolving in this period of uncertainty and are different from the adult population in certain aspects. Apart from the involvement of lungs, a multisystemic inflammatory syndrome in children or pediatric multi systemic inflammatory syndrome is unique in children. Therefore, awareness of the recent consensus, structural uniform reporting and multi-organ involving patterns in COVID-19 can guide radiologists for a better understanding of this complex novel disease leading to early diagnosis and timely treatment of affected children.