Browsing by Author "Anjum, Firoz"
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Publication Clinical and Laboratory Presentations in Children Admitted with Dengue Infection(Perinatal Society of Nepal (PESON), 2024) Ojha, Anil Raj; Nepal, Archana; Tuladhar, Sucharita; Shrestha, Shailesh; Anjum, Firoz; Gurung, GrishaAbstract: Introduction: Dengue fever, caused by the dengue virus, presents with a spectrum of symptoms, ranging from mild to severe. This study aims to identify common clinical symptoms and laboratory parameter abnormalities in children with dengue infection. Methods: A prospective observational study was conducted at Patan Hospital over three months. Clinical signs, symptoms, and laboratory parameters of seropositive children for dengue were recorded using a structured proforma. Results: During the study period, dengue fever accounted for 24% (104) of admissions in the children’s ward. Among these, 61% tested positive for the NS1 antigen alone, 21% for both IgM and NS1, and 17% for IgM only. The male-to-female ratio was 1.6:1, with an average age of 7 years (±4.37). 46.2% (47) had dengue without warning signs, 51.9% (57) had dengue with warning signs, and 1.9% (2) had severe dengue. Fever was present in all cases, with an average duration of 3.88 days. Vomiting, abdominal pain, head ache and epistaxis was present in 31.7%), 27.9%, 20.2%, 16.3% respectively. Hypotension was noted in 7.7% (8) of cases. Laboratory findings showed that 50% had a white blood cell count below 4000, and 54.8% had a platelet count below 150,000, with 12.2% below 50,000. Serial tests indicated elevated hematocrit levels in 35 patients. Most children were hospitalized for 4-6 days, with a mean stay of 4.65 days (±1.90). Conclusion: Dengue fever is a prevalent infection in children, typically presenting with high fever, vomiting, abdominal pain, headache, hypotension, low platelet count, elevated hematocrit, and leucopenia.Publication Congenital Upper Limb Deficiency with Oligodactyly: A Case Report(Nepal Medical Association, 2022) Twayana, Anu Radha; Sunuwar, Neela; Deo, Sulav; Rayamajhi, Sushil; Sherpa, Ninda Tashi Tenzing; Anjum, FirozAbstract Congenital upper limb deficiency care and management have undergone drastic changes over the past 50 years. Given the low incidence of this defect nationwide, this case report adds to the existing database to analyze the etiological investigations, descriptive epidemiology, and trend detection. We present a case of a 2-month-old male child with congenital upper limb deficiency and explore the possible etiologies and difficulties during early diagnosis of such rare disorders in a low and middle-income countrries and present implications at the primary health care level to improve the prognosis. Poor nutrition during pregnancy due to an unplanned pregnancy is a possible cause. The prognosis is unfavourable due to sociocultural barriers. To address these limitations, it is pertinent to address disability-adequate knowledge among communities, promote early diagnosis, and timely rehabilitation using a multidisciplinary approach. Further, we provide a framework to optimize care.